Primary study · included by 4 reviews
A prospective, randomized placebo-controlled clinical trial on the effects of a fluoride rinse on white spot lesion development and bleeding in orthodontic patients.
van der Kaaij et al. 2015 · van der Kaaij Nicoline C W, van der Veen Monique H, van der Kaaij Marleen A E, et al. · European journal of oral sciences · 2015
PubMed 25913893doi:10.1111/eos.12186Comparative Study; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
Trial PICO
Not extracted yet. Trial-level population, intervention, comparator, outcomes and design will appear here after the trial extraction run. Until then, the reviews below describe the study.
Results
Not extracted yet. Per-trial results (events, means, effect and weight as each review's forest plot reports them) will appear here after the trial extraction run.
Included by
The review does not say which of its outcomes this study informs.
The review does not say which of its outcomes this study informs.
The review does not say which of its outcomes this study informs.
| Outcome this study informs | Pooled effect | Evidence | Certainty |
|---|---|---|---|
Incidence of initial caries around brackets, aesthetic-zone teeth only Fluoride mouthrinse (0.05-0.32% sodium fluoride or amine fluoride) added to daily fluoride toothpaste vs Control: fluoride toothpaste alone, placebo mouthrinse + toothpaste, or non-fluoride (chlorhexidine) mouthrinse + toothpaste · At debonding (Gorelick index) | In two studies, a significant reduction of the incidence of initial caries around orthodontic brackets was reported in the FMR group when only teeth in the 'aesthetic zone' (central and lateral incisors, canines) were… | 2 studies | Ungraded |
Incidence of initial enamel caries / white spot lesions adjacent to bracket base (subject level, dichotomized) Fluoride mouthrinse (0.05-0.32% sodium fluoride or amine fluoride) added to daily fluoride toothpaste vs Control: fluoride toothpaste alone, placebo mouthrinse + toothpaste, or non-fluoride (chlorhexidine) mouthrinse + toothpaste · End of intervention (6-26 months) to within 6 weeks after debonding | RD -0.07 [-0.14, -0.01] | 5 studies · 491 participants | Ungraded |
4 including reviews in total.