Primary study · included by 2 reviews
Oral health and risk for head and neck squamous cell carcinoma: the Carolina Head and Neck Cancer Study.
Divaris 2010 · Divaris Kimon, Olshan Andrew F, Smith Joanna, et al. · Cancer causes & control : CCC · 2010
Included by
| Outcome this study informs | Pooled effect | Evidence | Certainty |
|---|---|---|---|
Risk, incidence or mortality of oral and/or oropharyngeal cancer Clinically defined periodontitis (exposure) vs No periodontitis or periodontally healthy | Pooled risk estimates ranged approximately from RR about 1.9 to 2.6 after sequential exclusion of each study, remaining above unity | 5 studies | GRADE not reported |
Risk, incidence or mortality of oral and/or oropharyngeal cancer Clinically defined periodontitis (exposure) vs No periodontitis or periodontally healthy | HR 2.14 [1.53, 2.98] | 6 studies | GRADE not reported |
| Outcome this study informs | Pooled effect | Evidence | Certainty |
|---|---|---|---|
Risk of head and neck cancer Periodontal diseases (gingivitis or periodontitis, as defined in each meta-analysis) vs No periodontal disease (absence of exposure) | OR 2.20 [1.19, 4.06] | 5 studies · 3257 participants | GRADE not reported |
Risk of head and neck cancer Periodontal diseases (gingivitis or periodontitis, as defined in each meta-analysis) vs No periodontal disease (absence of exposure) | OR 3.19 [2.09, 4.85] | 7 studies · 2464 participants | GRADE not reported |
Risk of head and neck cancer Periodontal diseases (gingivitis or periodontitis, as defined in each meta-analysis) vs No periodontal disease (absence of exposure) | OR 4.31 [1.56, 11.90] | 2 studies · 951 participants | GRADE not reported |
Risk of head and neck cancer Periodontal diseases (gingivitis or periodontitis, as defined in each meta-analysis) vs No periodontal disease (absence of exposure) | RR 1.07 [0.94, 1.23] | 5 studies · 1069853 participants | GRADE not reported |
Risk of head and neck cancer Periodontal diseases (gingivitis or periodontitis, as defined in each meta-analysis) vs No periodontal disease (absence of exposure) | RR 1.13 [0.80, 1.60] | 2 studies · 114244 participants | GRADE not reported |
Risk of head and neck cancer Periodontal diseases (gingivitis or periodontitis, as defined in each meta-analysis) vs No periodontal disease (absence of exposure) | OR 2.23 [0.58, 8.61] | 2 studies · 62304 participants | GRADE not reported |
Risk of head and neck cancer Periodontal diseases (gingivitis or periodontitis, as defined in each meta-analysis) vs No periodontal disease (absence of exposure) · Long follow-up | RR 0.97 [0.86, 1.11] | 3 studies · 961746 participants | GRADE not reported |
Risk of head and neck cancer Periodontal diseases (gingivitis or periodontitis, as defined in each meta-analysis) vs No periodontal disease (absence of exposure) | OR 2.46 [1.62, 3.74] | 8 studies · 71622 participants | GRADE not reported |
Risk of head and neck cancer Periodontal diseases (gingivitis or periodontitis, as defined in each meta-analysis) vs No periodontal disease (absence of exposure) | OR 2.67 [1.67, 4.27] | 2 studies · 2172 participants | GRADE not reported |
Risk of head and neck cancer Periodontal diseases (gingivitis or periodontitis, as defined in each meta-analysis) vs No periodontal disease (absence of exposure) | OR 4.68 [0.75, 29.33] | 2 studies · 4018 participants | GRADE not reported |
Risk of head and neck cancer Periodontal diseases (gingivitis or periodontitis, as defined in each meta-analysis) vs No periodontal disease (absence of exposure) | OR 3.17 [1.78, 5.64] | 9 studies · 82844 participants | GRADE not reported |
Risk of head and neck cancer Periodontal diseases (gingivitis or periodontitis, as defined in each meta-analysis) vs No periodontal disease (absence of exposure) | OR 2.45 [1.52, 3.94] | 7 studies · 57688 participants | GRADE not reported |
Risk of head and neck cancer Periodontal diseases (gingivitis or periodontitis, as defined in each meta-analysis) vs No periodontal disease (absence of exposure) | OR 2.29 [1.11, 4.76] | 4 studies · 63741 participants | GRADE not reported |
Risk of head and neck cancer Periodontal diseases (gingivitis or periodontitis, as defined in each meta-analysis) vs No periodontal disease (absence of exposure) · Short follow-up | RR 1.20 [1.09, 1.32] | 2 studies · 108107 participants | GRADE not reported |
Risk of head and neck cancer Periodontal diseases (gingivitis or periodontitis, as defined in each meta-analysis) vs No periodontal disease (absence of exposure) | RR 1.05 [0.88, 1.26] | 3 studies · 955609 participants | GRADE not reported |
Risk of head and neck cancer Periodontal diseases (gingivitis or periodontitis, as defined in each meta-analysis) vs No periodontal disease (absence of exposure) | OR 2.11 [0.74, 5.98] | 3 studies · 48902 participants | GRADE not reported |
Risk of head and neck cancer Periodontal diseases (gingivitis or periodontitis, as defined in each meta-analysis) vs No periodontal disease (absence of exposure) | OR 1.31 [1.10, 1.56] | 3 studies · 2306 participants | GRADE not reported |
Risk of head and neck cancer Periodontal diseases (gingivitis or periodontitis, as defined in each meta-analysis) vs No periodontal disease (absence of exposure) | OR 2.83 [1.83, 4.38] | 7 studies · 71722 participants | GRADE not reported |
Risk of head and neck cancer Periodontal diseases (gingivitis or periodontitis, as defined in each meta-analysis) vs No periodontal disease (absence of exposure) | OR 2.42 [1.85, 3.17] | 18 studies · 156693 participants | GRADE not reported |
2 including reviews in total.