Non-Cochrane · intervention · PM42321697
Comparison of universal adhesives used in different etching modes on dentin bond strength: a systematic review and network meta-analysis.
Karaduman Yesim Demirel, Ercan Mevlüde, Bedir Fatih, et al. · BMC oral health · 2026 · PubMed · doi:10.1186/s12903-026-08982-4
Findings
93 findings
| Population | ||||
|---|---|---|---|---|
| Sound permanent human (or bovine) dentin in laboratory specimens | Zipbond Universal (ZU) universal adhesive, self-etch mode | Scotchbond Universal (SBU) universal adhesive, same mode | Dentin bond strength (MPa) before ageing · Laboratory (in vitro) · Self-etch mode before ageing | MD -4.07 [-13.7, 5.44] GRADE not reported 77 studies · 2580 participants |
| Sound permanent human (or bovine) dentin in laboratory specimens | Futurabond U (FU) universal adhesive, self-etch mode | Scotchbond Universal (SBU) universal adhesive, same mode | Dentin bond strength (MPa) before ageing · Laboratory (in vitro) · Self-etch mode before ageing | MD -9.36 [-16.3, -2.45] GRADE not reported 77 studies · 2580 participants |
| Sound permanent human (or bovine) dentin in laboratory specimens | Beautibond Xtreme Universal (BXU) universal adhesive, self-etch mode | Scotchbond Universal (SBU) universal adhesive, same mode | Dentin bond strength (MPa) before ageing · Laboratory (in vitro) · Self-etch mode before ageing | MD -10.0 [-24.6, 4.82] GRADE not reported 77 studies · 2580 participants |
| Sound permanent human (or bovine) dentin in laboratory specimens | Prime&Bond Active (PBA) universal adhesive, self-etch mode | Scotchbond Universal (SBU) universal adhesive, same mode | Dentin bond strength (MPa) before ageing · Laboratory (in vitro) · Self-etch mode before ageing | MD -2.75 [-8.32, 2.88] GRADE not reported 77 studies · 2580 participants |
| Sound permanent human (or bovine) dentin in laboratory specimens | Clearfil Universal Bond Quick (CUBQ) universal adhesive, self-etch mode | Scotchbond Universal (SBU) universal adhesive, same mode | Dentin bond strength (MPa) before ageing · Laboratory (in vitro) · Self-etch mode before ageing | MD -4.76 [-10.4, 0.8] GRADE not reported 77 studies · 2580 participants |
| Sound permanent human (or bovine) dentin in laboratory specimens | Tetric N-Bond Universal (TNB) universal adhesive, self-etch mode | Scotchbond Universal (SBU) universal adhesive, same mode | Dentin bond strength (MPa) before ageing · Laboratory (in vitro) · Self-etch mode before ageing | MD -2.73 [-9.47, 4.03] GRADE not reported 77 studies · 2580 participants |
| Sound permanent human (or bovine) dentin in laboratory specimens | Ybond Universal (YU) universal adhesive, self-etch mode | Scotchbond Universal (SBU) universal adhesive, same mode | Dentin bond strength (MPa) before ageing · Laboratory (in vitro) · Self-etch mode before ageing | MD -12.4 [-29.0, 3.87] GRADE not reported 77 studies · 2580 participants |
| Sound permanent human (or bovine) dentin in laboratory specimens | RE-GEN Universal (RUA) universal adhesive, self-etch mode | Scotchbond Universal (SBU) universal adhesive, same mode | Dentin bond strength (MPa) before ageing · Laboratory (in vitro) · Self-etch mode before ageing | MD -0.556 [-14.5, 13.5] GRADE not reported 77 studies · 2580 participants |
| Sound permanent human (or bovine) dentin in laboratory specimens | Adhese Universal (AU) universal adhesive, self-etch mode | Scotchbond Universal (SBU) universal adhesive, same mode | Dentin bond strength (MPa) before ageing · Laboratory (in vitro) · Self-etch mode before ageing | MD -8.24 [-13.3, -3.21] GRADE not reported 77 studies · 2580 participants |
| Sound permanent human (or bovine) dentin in laboratory specimens | Clearfil Universal Bond (CUB) universal adhesive, self-etch mode | Scotchbond Universal (SBU) universal adhesive, same mode | Dentin bond strength (MPa) before ageing · Laboratory (in vitro) · Self-etch mode before ageing | MD -8.07 [-12.3, -3.84] GRADE not reported 77 studies · 2580 participants |
| Sound permanent human (or bovine) dentin in laboratory specimens | Prime&Bond Elect (PBE) universal adhesive, self-etch mode | Scotchbond Universal (SBU) universal adhesive, same mode | Dentin bond strength (MPa) before ageing · Laboratory (in vitro) · Self-etch mode before ageing | MD -8.2 [-12.6, -3.77] GRADE not reported 77 studies · 2580 participants |
| Sound permanent human (or bovine) dentin in laboratory specimens | OptiBond Universal (OBU) universal adhesive, self-etch mode | Scotchbond Universal (SBU) universal adhesive, same mode | Dentin bond strength (MPa) before ageing · Laboratory (in vitro) · Self-etch mode before ageing | MD 3.27 [-7.32, 13.8] GRADE not reported 77 studies · 2580 participants |
| Sound permanent human (or bovine) dentin in laboratory specimens | One Coat 7 Universal (O7U) universal adhesive, self-etch mode | Scotchbond Universal (SBU) universal adhesive, same mode | Dentin bond strength (MPa) before ageing · Laboratory (in vitro) · Self-etch mode before ageing | MD -7.23 [-16.6, 2.18] GRADE not reported 77 studies · 2580 participants |
| Sound permanent human (or bovine) dentin in laboratory specimens | Gluma Bond Universal (GBU) universal adhesive, self-etch mode | Scotchbond Universal (SBU) universal adhesive, same mode | Dentin bond strength (MPa) before ageing · Laboratory (in vitro) · Self-etch mode before ageing | MD -7.99 [-14.3, -1.72] GRADE not reported 77 studies · 2580 participants |
| Sound permanent human (or bovine) dentin in laboratory specimens | iBOND Universal (IBU) universal adhesive, self-etch mode | Scotchbond Universal (SBU) universal adhesive, same mode | Dentin bond strength (MPa) before ageing · Laboratory (in vitro) · Self-etch mode before ageing | MD -10.0 [-23.1, 3.09] GRADE not reported 77 studies · 2580 participants |
| Sound permanent human (or bovine) dentin in laboratory specimens | Ambar Universal (AUB) universal adhesive, self-etch mode | Scotchbond Universal (SBU) universal adhesive, same mode | Dentin bond strength (MPa) before ageing · Laboratory (in vitro) · Self-etch mode before ageing | MD -0.256 [-6.5, 6.01] GRADE not reported 77 studies · 2580 participants |
| Sound permanent human (or bovine) dentin in laboratory specimens | G-Premio Bond (GPB) universal adhesive, self-etch mode | Scotchbond Universal (SBU) universal adhesive, same mode | Dentin bond strength (MPa) before ageing · Laboratory (in vitro) · Self-etch mode before ageing | MD -10.7 [-13.6, -7.83] GRADE not reported 77 studies · 2580 participants |
| Sound permanent human (or bovine) dentin in laboratory specimens | All-Bond Universal (ABU) universal adhesive, self-etch mode | Scotchbond Universal (SBU) universal adhesive, same mode | Dentin bond strength (MPa) before ageing · Laboratory (in vitro) · Self-etch mode before ageing | MD -8.69 [-11.4, -5.96] GRADE not reported 77 studies · 2580 participants |
| Sound permanent human (or bovine) dentin in laboratory specimens | Tokuyama Universal (TUB) universal adhesive, self-etch mode | Scotchbond Universal (SBU) universal adhesive, same mode | Dentin bond strength (MPa) before ageing · Laboratory (in vitro) · Self-etch mode before ageing | MD -13.8 [-19.8, -7.86] GRADE not reported 77 studies · 2580 participants |
| Sound permanent human (or bovine) dentin in laboratory specimens | Peak Universal Bond (PUB) universal adhesive, self-etch mode | Scotchbond Universal (SBU) universal adhesive, same mode | Dentin bond strength (MPa) before ageing · Laboratory (in vitro) · Self-etch mode before ageing | MD -3.37 [-13.3, 6.56] GRADE not reported 77 studies · 2580 participants |
| Sound permanent human (or bovine) dentin in laboratory specimens | G2-Bond Universal (G2BU) universal adhesive, self-etch mode | Scotchbond Universal (SBU) universal adhesive, same mode | Dentin bond strength (MPa) before ageing · Laboratory (in vitro) · Self-etch mode before ageing | MD 4.81 [-1.9, 11.5] GRADE not reported 77 studies · 2580 participants |
| Sound permanent human (or bovine) dentin in laboratory specimens | Ambar Universal (AUB) universal adhesive, etch-and-rinse mode | Scotchbond Universal (SBU) universal adhesive, same mode | Dentin bond strength (MPa) before ageing · Laboratory (in vitro) · Etch-and-rinse mode before ageing | MD -3.82 [-9.54, 1.85] GRADE not reported 46 studies · 1755 participants |
| Sound permanent human (or bovine) dentin in laboratory specimens | Gluma Bond Universal (GBU) universal adhesive, etch-and-rinse mode | Scotchbond Universal (SBU) universal adhesive, same mode | Dentin bond strength (MPa) before ageing · Laboratory (in vitro) · Etch-and-rinse mode before ageing | MD -3.85 [-10.0, 2.41] GRADE not reported 46 studies · 1755 participants |
| Sound permanent human (or bovine) dentin in laboratory specimens | All-Bond Universal (ABU) universal adhesive, etch-and-rinse mode | Scotchbond Universal (SBU) universal adhesive, same mode | Dentin bond strength (MPa) before ageing · Laboratory (in vitro) · Etch-and-rinse mode before ageing | MD -0.114 [-2.55, 2.35] GRADE not reported 46 studies · 1755 participants |
| Sound permanent human (or bovine) dentin in laboratory specimens | Tetric N-Bond Universal (TNB) universal adhesive, etch-and-rinse mode | Scotchbond Universal (SBU) universal adhesive, same mode | Dentin bond strength (MPa) before ageing · Laboratory (in vitro) · Etch-and-rinse mode before ageing | MD 1.49 [-5.28, 8.15] GRADE not reported 46 studies · 1755 participants |
| Sound permanent human (or bovine) dentin in laboratory specimens | iBOND Universal (IBU) universal adhesive, etch-and-rinse mode | Scotchbond Universal (SBU) universal adhesive, same mode | Dentin bond strength (MPa) before ageing · Laboratory (in vitro) · Etch-and-rinse mode before ageing | MD -5.76 [-16.0, 4.4] GRADE not reported 46 studies · 1755 participants |
| Sound permanent human (or bovine) dentin in laboratory specimens | Clearfil Universal Bond (CUB) universal adhesive, etch-and-rinse mode | Scotchbond Universal (SBU) universal adhesive, same mode | Dentin bond strength (MPa) before ageing · Laboratory (in vitro) · Etch-and-rinse mode before ageing | MD -2.28 [-6.87, 2.36] GRADE not reported 46 studies · 1755 participants |
| Sound permanent human (or bovine) dentin in laboratory specimens | G2-Bond Universal (G2BU) universal adhesive, etch-and-rinse mode | Scotchbond Universal (SBU) universal adhesive, same mode | Dentin bond strength (MPa) before ageing · Laboratory (in vitro) · Etch-and-rinse mode before ageing | MD -2.03 [-13.7, 9.8] GRADE not reported 46 studies · 1755 participants |
| Sound permanent human (or bovine) dentin in laboratory specimens | Prime&Bond Active (PBA) universal adhesive, etch-and-rinse mode | Scotchbond Universal (SBU) universal adhesive, same mode | Dentin bond strength (MPa) before ageing · Laboratory (in vitro) · Etch-and-rinse mode before ageing | MD -1.21 [-5.28, 2.9] GRADE not reported 46 studies · 1755 participants |
| Sound permanent human (or bovine) dentin in laboratory specimens | Prime&Bond Elect (PBE) universal adhesive, etch-and-rinse mode | Scotchbond Universal (SBU) universal adhesive, same mode | Dentin bond strength (MPa) before ageing · Laboratory (in vitro) · Etch-and-rinse mode before ageing | MD -6.79 [-11.4, -2.14] GRADE not reported 46 studies · 1755 participants |
| Sound permanent human (or bovine) dentin in laboratory specimens | Futurabond U (FU) universal adhesive, etch-and-rinse mode | Scotchbond Universal (SBU) universal adhesive, same mode | Dentin bond strength (MPa) before ageing · Laboratory (in vitro) · Etch-and-rinse mode before ageing | MD -9.74 [-14.6, -5.16] GRADE not reported 46 studies · 1755 participants |
| Sound permanent human (or bovine) dentin in laboratory specimens | Zipbond Universal (ZU) universal adhesive, etch-and-rinse mode | Scotchbond Universal (SBU) universal adhesive, same mode | Dentin bond strength (MPa) before ageing · Laboratory (in vitro) · Etch-and-rinse mode before ageing | MD 4.61 [-1.09, 10.3] GRADE not reported 46 studies · 1755 participants |
| Sound permanent human (or bovine) dentin in laboratory specimens | Tokuyama Universal (TUB) universal adhesive, etch-and-rinse mode | Scotchbond Universal (SBU) universal adhesive, same mode | Dentin bond strength (MPa) before ageing · Laboratory (in vitro) · Etch-and-rinse mode before ageing | MD -2.51 [-10.2, 5.28] GRADE not reported 46 studies · 1755 participants |
| Sound permanent human (or bovine) dentin in laboratory specimens | Adhese Universal (AU) universal adhesive, etch-and-rinse mode | Scotchbond Universal (SBU) universal adhesive, same mode | Dentin bond strength (MPa) before ageing · Laboratory (in vitro) · Etch-and-rinse mode before ageing | MD 0.921 [-3.24, 5.16] GRADE not reported 46 studies · 1755 participants |
| Sound permanent human (or bovine) dentin in laboratory specimens | Ybond Universal (YU) universal adhesive, etch-and-rinse mode | Scotchbond Universal (SBU) universal adhesive, same mode | Dentin bond strength (MPa) before ageing · Laboratory (in vitro) · Etch-and-rinse mode before ageing | MD -6.63 [-19.0, 5.78] GRADE not reported 46 studies · 1755 participants |
| Sound permanent human (or bovine) dentin in laboratory specimens | Clearfil Universal Bond Quick (CUBQ) universal adhesive, etch-and-rinse mode | Scotchbond Universal (SBU) universal adhesive, same mode | Dentin bond strength (MPa) before ageing · Laboratory (in vitro) · Etch-and-rinse mode before ageing | MD -3.11 [-7.31, 1.15] GRADE not reported 46 studies · 1755 participants |
| Sound permanent human (or bovine) dentin in laboratory specimens | Peak Universal Bond (PUB) universal adhesive, etch-and-rinse mode | Scotchbond Universal (SBU) universal adhesive, same mode | Dentin bond strength (MPa) before ageing · Laboratory (in vitro) · Etch-and-rinse mode before ageing | MD 0.301 [-4.75, 5.45] GRADE not reported 46 studies · 1755 participants |
| Sound permanent human (or bovine) dentin in laboratory specimens | G-Premio Bond (GPB) universal adhesive, etch-and-rinse mode | Scotchbond Universal (SBU) universal adhesive, same mode | Dentin bond strength (MPa) before ageing · Laboratory (in vitro) · Etch-and-rinse mode before ageing | MD -4.56 [-8.07, -0.961] GRADE not reported 46 studies · 1755 participants |
| Sound permanent human (or bovine) dentin in laboratory specimens | Beautibond Universal (BU) universal adhesive, self-etch mode | Scotchbond Universal (SBU) universal adhesive, same mode | Dentin bond strength (MPa) after ageing · Laboratory (in vitro) · Self-etch mode after ageing | MD -11.1 [-23.6, 1.26] GRADE not reported 46 studies · 1452 participants |
| Sound permanent human (or bovine) dentin in laboratory specimens | Peak Universal Bond (PUB) universal adhesive, self-etch mode | Scotchbond Universal (SBU) universal adhesive, same mode | Dentin bond strength (MPa) after ageing · Laboratory (in vitro) · Self-etch mode after ageing | MD -5.68 [-20.0, 8.55] GRADE not reported 46 studies · 1452 participants |
| Sound permanent human (or bovine) dentin in laboratory specimens | Ambar Universal (AUB) universal adhesive, self-etch mode | Scotchbond Universal (SBU) universal adhesive, same mode | Dentin bond strength (MPa) after ageing · Laboratory (in vitro) · Self-etch mode after ageing | MD -0.307 [-6.02, 5.36] GRADE not reported 46 studies · 1452 participants |
| Sound permanent human (or bovine) dentin in laboratory specimens | All-Bond Universal (ABU) universal adhesive, self-etch mode | Scotchbond Universal (SBU) universal adhesive, same mode | Dentin bond strength (MPa) after ageing · Laboratory (in vitro) · Self-etch mode after ageing | MD -3.51 [-6.44, -0.653] GRADE not reported 46 studies · 1452 participants |
| Sound permanent human (or bovine) dentin in laboratory specimens | Adhese Universal (AU) universal adhesive, self-etch mode | Scotchbond Universal (SBU) universal adhesive, same mode | Dentin bond strength (MPa) after ageing · Laboratory (in vitro) · Self-etch mode after ageing | MD -4.26 [-9.8, 1.27] GRADE not reported 46 studies · 1452 participants |
| Sound permanent human (or bovine) dentin in laboratory specimens | Tetric N-Bond Universal (TNB) universal adhesive, self-etch mode | Scotchbond Universal (SBU) universal adhesive, same mode | Dentin bond strength (MPa) after ageing · Laboratory (in vitro) · Self-etch mode after ageing | MD -1.04 [-7.77, 5.77] GRADE not reported 46 studies · 1452 participants |
| Sound permanent human (or bovine) dentin in laboratory specimens | iBOND Universal (IBU) universal adhesive, self-etch mode | Scotchbond Universal (SBU) universal adhesive, same mode | Dentin bond strength (MPa) after ageing · Laboratory (in vitro) · Self-etch mode after ageing | MD -6.14 [-17.7, 5.29] GRADE not reported 46 studies · 1452 participants |
| Sound permanent human (or bovine) dentin in laboratory specimens | Futurabond U (FU) universal adhesive, self-etch mode | Scotchbond Universal (SBU) universal adhesive, same mode | Dentin bond strength (MPa) after ageing · Laboratory (in vitro) · Self-etch mode after ageing | MD -13.1 [-22.2, -4.04] GRADE not reported 46 studies · 1452 participants |
| Sound permanent human (or bovine) dentin in laboratory specimens | Tokuyama Universal (TUB) universal adhesive, self-etch mode | Scotchbond Universal (SBU) universal adhesive, same mode | Dentin bond strength (MPa) after ageing · Laboratory (in vitro) · Self-etch mode after ageing | MD -9.29 [-17.2, -1.48] GRADE not reported 46 studies · 1452 participants |
| Sound permanent human (or bovine) dentin in laboratory specimens | Gluma Bond Universal (GBU) universal adhesive, self-etch mode | Scotchbond Universal (SBU) universal adhesive, same mode | Dentin bond strength (MPa) after ageing · Laboratory (in vitro) · Self-etch mode after ageing | MD -7.71 [-13.8, -1.6] GRADE not reported 46 studies · 1452 participants |
| Sound permanent human (or bovine) dentin in laboratory specimens | Prime&Bond Elect (PBE) universal adhesive, self-etch mode | Scotchbond Universal (SBU) universal adhesive, same mode | Dentin bond strength (MPa) after ageing · Laboratory (in vitro) · Self-etch mode after ageing | MD -1.76 [-8.33, 4.72] GRADE not reported 46 studies · 1452 participants |
| Sound permanent human (or bovine) dentin in laboratory specimens | Clearfil Universal Bond (CUB) universal adhesive, self-etch mode | Scotchbond Universal (SBU) universal adhesive, same mode | Dentin bond strength (MPa) after ageing · Laboratory (in vitro) · Self-etch mode after ageing | MD -5.03 [-9.55, -0.407] GRADE not reported 46 studies · 1452 participants |
| Sound permanent human (or bovine) dentin in laboratory specimens | RE-GEN Universal (RUA) universal adhesive, self-etch mode | Scotchbond Universal (SBU) universal adhesive, same mode | Dentin bond strength (MPa) after ageing · Laboratory (in vitro) · Self-etch mode after ageing | MD -7.49 [-19.1, 4.26] GRADE not reported 46 studies · 1452 participants |
| Sound permanent human (or bovine) dentin in laboratory specimens | OptiBond Universal (OBU) universal adhesive, self-etch mode | Scotchbond Universal (SBU) universal adhesive, same mode | Dentin bond strength (MPa) after ageing · Laboratory (in vitro) · Self-etch mode after ageing | MD 0.776 [-12.4, 14.0] GRADE not reported 46 studies · 1452 participants |
| Sound permanent human (or bovine) dentin in laboratory specimens | Ybond Universal (YU) universal adhesive, self-etch mode | Scotchbond Universal (SBU) universal adhesive, same mode | Dentin bond strength (MPa) after ageing · Laboratory (in vitro) · Self-etch mode after ageing | MD -6.02 [-17.7, 5.83] GRADE not reported 46 studies · 1452 participants |
| Sound permanent human (or bovine) dentin in laboratory specimens | Zipbond Universal (ZU) universal adhesive, self-etch mode | Scotchbond Universal (SBU) universal adhesive, same mode | Dentin bond strength (MPa) after ageing · Laboratory (in vitro) · Self-etch mode after ageing | MD 1.42 [-6.64, 9.54] GRADE not reported 46 studies · 1452 participants |
| Sound permanent human (or bovine) dentin in laboratory specimens | G2-Bond Universal (G2BU) universal adhesive, self-etch mode | Scotchbond Universal (SBU) universal adhesive, same mode | Dentin bond strength (MPa) after ageing · Laboratory (in vitro) · Self-etch mode after ageing | MD 2.07 [-4.12, 8.33] GRADE not reported 46 studies · 1452 participants |
| Sound permanent human (or bovine) dentin in laboratory specimens | Clearfil Universal Bond Quick (CUBQ) universal adhesive, self-etch mode | Scotchbond Universal (SBU) universal adhesive, same mode | Dentin bond strength (MPa) after ageing · Laboratory (in vitro) · Self-etch mode after ageing | MD -10.7 [-16.1, -5.34] GRADE not reported 46 studies · 1452 participants |
| Sound permanent human (or bovine) dentin in laboratory specimens | G-Premio Bond (GPB) universal adhesive, self-etch mode | Scotchbond Universal (SBU) universal adhesive, same mode | Dentin bond strength (MPa) after ageing · Laboratory (in vitro) · Self-etch mode after ageing | MD -7.7 [-11.6, -3.88] GRADE not reported 46 studies · 1452 participants |
| Sound permanent human (or bovine) dentin in laboratory specimens | Beautibond Xtreme Universal (BXU) universal adhesive, self-etch mode | Scotchbond Universal (SBU) universal adhesive, same mode | Dentin bond strength (MPa) after ageing · Laboratory (in vitro) · Self-etch mode after ageing | MD -5.81 [-17.7, 6.16] GRADE not reported 46 studies · 1452 participants |
| Sound permanent human (or bovine) dentin in laboratory specimens | Prime&Bond Active (PBA) universal adhesive, self-etch mode | Scotchbond Universal (SBU) universal adhesive, same mode | Dentin bond strength (MPa) after ageing · Laboratory (in vitro) · Self-etch mode after ageing | MD -0.465 [-5.54, 4.65] GRADE not reported 46 studies · 1452 participants |
| Sound permanent human (or bovine) dentin in laboratory specimens | Tetric N-Bond Universal (TNB) universal adhesive, etch-and-rinse mode | Scotchbond Universal (SBU) universal adhesive, same mode | Dentin bond strength (MPa) after ageing · Laboratory (in vitro) · Etch-and-rinse mode after ageing | MD -9.68 [-20.0, 0.694] GRADE not reported 24 studies · 803 participants |
| Sound permanent human (or bovine) dentin in laboratory specimens | Ambar Universal (AUB) universal adhesive, etch-and-rinse mode | Scotchbond Universal (SBU) universal adhesive, same mode | Dentin bond strength (MPa) after ageing · Laboratory (in vitro) · Etch-and-rinse mode after ageing | MD -4.7 [-10.6, 1.23] GRADE not reported 24 studies · 803 participants |
| Sound permanent human (or bovine) dentin specimens (in vitro) | Beautibond Universal applied in self-etch mode | Scotchbond Universal (SBU) | Rank of dentin bond strength (SUCRA) After ageing · Laboratory (in vitro) dentin bonding · Self-etch mode | SUCRA (%) 78.81 GRADE not reported 46 studies · 1452 specimens in network participants |
| Sound permanent human (or bovine) dentin in laboratory specimens | Prime&Bond Active (PBA) universal adhesive, etch-and-rinse mode | Scotchbond Universal (SBU) universal adhesive, same mode | Dentin bond strength (MPa) after ageing · Laboratory (in vitro) · Etch-and-rinse mode after ageing | MD -5.49 [-11.3, 0.414] GRADE not reported 24 studies · 803 participants |
| Sound permanent human (or bovine) dentin in laboratory specimens | Peak Universal Bond (PUB) universal adhesive, etch-and-rinse mode | Scotchbond Universal (SBU) universal adhesive, same mode | Dentin bond strength (MPa) after ageing · Laboratory (in vitro) · Etch-and-rinse mode after ageing | MD -0.434 [-11.5, 10.7] GRADE not reported 24 studies · 803 participants |
| Sound permanent human (or bovine) dentin in laboratory specimens | Gluma Bond Universal (GBU) universal adhesive, etch-and-rinse mode | Scotchbond Universal (SBU) universal adhesive, same mode | Dentin bond strength (MPa) after ageing · Laboratory (in vitro) · Etch-and-rinse mode after ageing | MD -2.65 [-10.1, 4.76] GRADE not reported 24 studies · 803 participants |
| Sound permanent human (or bovine) dentin in laboratory specimens | Clearfil Universal Bond Quick (CUBQ) universal adhesive, etch-and-rinse mode | Scotchbond Universal (SBU) universal adhesive, same mode | Dentin bond strength (MPa) after ageing · Laboratory (in vitro) · Etch-and-rinse mode after ageing | MD -15.4 [-21.7, -8.85] GRADE not reported 24 studies · 803 participants |
| Sound permanent human (or bovine) dentin in laboratory specimens | Adhese Universal (AU) universal adhesive, etch-and-rinse mode | Scotchbond Universal (SBU) universal adhesive, same mode | Dentin bond strength (MPa) after ageing · Laboratory (in vitro) · Etch-and-rinse mode after ageing | MD -1.75 [-10.3, 6.81] GRADE not reported 24 studies · 803 participants |
| Sound permanent human (or bovine) dentin in laboratory specimens | Futurabond U (FU) universal adhesive, etch-and-rinse mode | Scotchbond Universal (SBU) universal adhesive, same mode | Dentin bond strength (MPa) after ageing · Laboratory (in vitro) · Etch-and-rinse mode after ageing | MD -6.78 [-13.6, -0.0345] GRADE not reported 24 studies · 803 participants |
| Sound permanent human (or bovine) dentin in laboratory specimens | iBOND Universal (IBU) universal adhesive, etch-and-rinse mode | Scotchbond Universal (SBU) universal adhesive, same mode | Dentin bond strength (MPa) after ageing · Laboratory (in vitro) · Etch-and-rinse mode after ageing | MD -15.0 [-24.3, -5.77] GRADE not reported 24 studies · 803 participants |
| Sound permanent human (or bovine) dentin in laboratory specimens | All-Bond Universal (ABU) universal adhesive, etch-and-rinse mode | Scotchbond Universal (SBU) universal adhesive, same mode | Dentin bond strength (MPa) after ageing · Laboratory (in vitro) · Etch-and-rinse mode after ageing | MD 0.612 [-2.37, 3.56] GRADE not reported 24 studies · 803 participants |
| Sound permanent human (or bovine) dentin in laboratory specimens | G2-Bond Universal (G2BU) universal adhesive, etch-and-rinse mode | Scotchbond Universal (SBU) universal adhesive, same mode | Dentin bond strength (MPa) after ageing · Laboratory (in vitro) · Etch-and-rinse mode after ageing | MD -6.03 [-19.3, 7.25] GRADE not reported 24 studies · 803 participants |
| Sound permanent human (or bovine) dentin in laboratory specimens | Tokuyama Universal (TUB) universal adhesive, etch-and-rinse mode | Scotchbond Universal (SBU) universal adhesive, same mode | Dentin bond strength (MPa) after ageing · Laboratory (in vitro) · Etch-and-rinse mode after ageing | MD -1.17 [-14.6, 12.1] GRADE not reported 24 studies · 803 participants |
| Sound permanent human (or bovine) dentin in laboratory specimens | G-Premio Bond (GPB) universal adhesive, etch-and-rinse mode | Scotchbond Universal (SBU) universal adhesive, same mode | Dentin bond strength (MPa) after ageing · Laboratory (in vitro) · Etch-and-rinse mode after ageing | MD -9.54 [-16.2, -2.84] GRADE not reported 24 studies · 803 participants |
| Sound permanent human (or bovine) dentin in laboratory specimens | Ybond Universal (YU) universal adhesive, etch-and-rinse mode | Scotchbond Universal (SBU) universal adhesive, same mode | Dentin bond strength (MPa) after ageing · Laboratory (in vitro) · Etch-and-rinse mode after ageing | MD 0.475 [-12.5, 13.5] GRADE not reported 24 studies · 803 participants |
| Sound permanent human (or bovine) dentin in laboratory specimens | Prime&Bond Elect (PBE) universal adhesive, etch-and-rinse mode | Scotchbond Universal (SBU) universal adhesive, same mode | Dentin bond strength (MPa) after ageing · Laboratory (in vitro) · Etch-and-rinse mode after ageing | MD -0.517 [-7.18, 5.97] GRADE not reported 24 studies · 803 participants |
| Sound permanent human (or bovine) dentin in laboratory specimens | Zipbond Universal (ZU) universal adhesive, etch-and-rinse mode | Scotchbond Universal (SBU) universal adhesive, same mode | Dentin bond strength (MPa) after ageing · Laboratory (in vitro) · Etch-and-rinse mode after ageing | MD 6.99 [0.21, 13.8] GRADE not reported 24 studies · 803 participants |
| Sound permanent human (or bovine) dentin in laboratory specimens | Clearfil Universal Bond (CUB) universal adhesive, etch-and-rinse mode | Scotchbond Universal (SBU) universal adhesive, same mode | Dentin bond strength (MPa) after ageing · Laboratory (in vitro) · Etch-and-rinse mode after ageing | MD -2.88 [-9.62, 3.62] GRADE not reported 24 studies · 803 participants |
| Sound permanent human (or bovine) dentin specimens (in vitro) | Clearfil Universal Bond Quick applied in self-etch mode | Scotchbond Universal (SBU) | Rank of dentin bond strength (SUCRA) After ageing · Laboratory (in vitro) dentin bonding · Self-etch mode | SUCRA (%) 83.74 GRADE not reported 46 studies · 1452 specimens in network participants |
| Sound permanent human (or bovine) dentin specimens (in vitro) | Clearfil Universal Bond Quick applied in etch-and-rinse mode | Scotchbond Universal (SBU) | Rank of dentin bond strength (SUCRA) After ageing · Laboratory (in vitro) dentin bonding · Etch-and-rinse mode | SUCRA (%) 94.17 GRADE not reported 24 studies · 803 specimens in network participants |
| Sound permanent human (or bovine) dentin specimens (in vitro) | Futurabond U applied in self-etch mode | Scotchbond Universal (SBU) | Rank of dentin bond strength (SUCRA) After ageing · Laboratory (in vitro) dentin bonding · Self-etch mode | SUCRA (%) 88.38 GRADE not reported 46 studies · 1452 specimens in network participants |
| Sound permanent human (or bovine) dentin specimens (in vitro) | Futurabond U applied in etch-and-rinse mode | Scotchbond Universal (SBU) | Rank of dentin bond strength (SUCRA) Before ageing (24 h or 1 week) · Laboratory (in vitro) dentin bonding · Etch-and-rinse mode | SUCRA (%) 93.71 GRADE not reported 46 studies · 1755 specimens in network participants |
| Sound permanent human (or bovine) dentin specimens (in vitro) | G2-Bond Universal applied in self-etch mode | Scotchbond Universal (SBU) | Rank of dentin bond strength (SUCRA) After ageing · Laboratory (in vitro) dentin bonding · Self-etch mode | SUCRA (%) 13.74 GRADE not reported 46 studies · 1452 specimens in network participants |
| Sound permanent human (or bovine) dentin specimens (in vitro) | G2-Bond Universal applied in self-etch mode | Scotchbond Universal (SBU) | Rank of dentin bond strength (SUCRA) Before ageing (24 h or 1 week) · Laboratory (in vitro) dentin bonding · Self-etch mode | SUCRA (%) 5.86 GRADE not reported 77 studies · 2580 specimens in network participants |
| Sound permanent human (or bovine) dentin specimens (in vitro) | G-Premio Bond applied in self-etch mode | Scotchbond Universal (SBU) | Rank of dentin bond strength (SUCRA) Before ageing (24 h or 1 week) · Laboratory (in vitro) dentin bonding · Self-etch mode | SUCRA (%) 80.69 GRADE not reported 77 studies · 2580 specimens in network participants |
| Sound permanent human (or bovine) dentin specimens (in vitro) | iBOND Universal applied in etch-and-rinse mode | Scotchbond Universal (SBU) | Rank of dentin bond strength (SUCRA) After ageing · Laboratory (in vitro) dentin bonding · Etch-and-rinse mode | SUCRA (%) 92.07 GRADE not reported 24 studies · 803 specimens in network participants |
| Sound permanent human (or bovine) dentin specimens (in vitro) | OptiBond Universal applied in self-etch mode | Scotchbond Universal (SBU) | Rank of dentin bond strength (SUCRA) Before ageing (24 h or 1 week) · Laboratory (in vitro) dentin bonding · Self-etch mode | SUCRA (%) 12.53 GRADE not reported 77 studies · 2580 specimens in network participants |
| Sound permanent human (or bovine) dentin specimens (in vitro) | Tokuyama Universal applied in self-etch mode | Scotchbond Universal (SBU) | Rank of dentin bond strength (SUCRA) Before ageing (24 h or 1 week) · Laboratory (in vitro) dentin bonding · Self-etch mode | SUCRA (%) 90.54 GRADE not reported 77 studies · 2580 specimens in network participants |
| Sound permanent human (or bovine) dentin specimens (in vitro) | Ybond Universal applied in self-etch mode | Scotchbond Universal (SBU) | Rank of dentin bond strength (SUCRA) Before ageing (24 h or 1 week) · Laboratory (in vitro) dentin bonding · Self-etch mode | SUCRA (%) 75.14 GRADE not reported 77 studies · 2580 specimens in network participants |
| Sound permanent human (or bovine) dentin specimens (in vitro) | Zipbond Universal applied in etch-and-rinse mode | Scotchbond Universal (SBU) | Rank of dentin bond strength (SUCRA) Before ageing (24 h or 1 week) · Laboratory (in vitro) dentin bonding · Etch-and-rinse mode | SUCRA (%) 6.32 GRADE not reported 46 studies · 1755 specimens in network participants |
| Sound permanent human (or bovine) dentin specimens (in vitro) | Zipbond Universal applied in self-etch mode | Scotchbond Universal (SBU) | Rank of dentin bond strength (SUCRA) After ageing · Laboratory (in vitro) dentin bonding · Self-etch mode | SUCRA (%) 18.47 GRADE not reported 46 studies · 1452 specimens in network participants |
| Sound permanent human (or bovine) dentin specimens (in vitro) | Zipbond Universal applied in etch-and-rinse mode | Scotchbond Universal (SBU) | Rank of dentin bond strength (SUCRA) After ageing · Laboratory (in vitro) dentin bonding · Etch-and-rinse mode | SUCRA (%) 4.21 GRADE not reported 24 studies · 803 specimens in network participants |
| Sound permanent human (or bovine) dentin specimens (in vitro) | Scotchbond Universal (SBU) (reference adhesive) | Other universal adhesives in the network | Rank of dentin bond strength (SUCRA) After ageing · Laboratory (in vitro) dentin bonding · Self-etch mode | SUCRA (%) 21.03 GRADE not reported 46 studies · 1452 specimens in network participants |
| Sound permanent human (or bovine) dentin specimens (in vitro) | Scotchbond Universal (SBU) (reference adhesive) | Other universal adhesives in the network | Rank of dentin bond strength (SUCRA) Before ageing (24 h or 1 week) · Laboratory (in vitro) dentin bonding · Self-etch mode | SUCRA (%) 17.94 GRADE not reported 77 studies · 2580 specimens in network participants |
Included primary studies 152
Open in Studies| Study | Year | Also included by | Outcomes it informs here | Trial data |
|---|---|---|---|---|
| Markham 2020 Influence of 38% silver diamine fluoride application on bond stability to enamel and dentin using universal adhesives in self‐etch mode DOI:10.1111/eos.12701 | 2020 | 1 other review | not stated | not extracted yet |
| Markham 2020 Influence of 38% silver diamine fluoride application on bond stability to enamel and dentin using universal adhesives in self-etch mode. PMID:32395905 | 2020 | 1 other review | not stated | not extracted yet |
| Acurio-Benavente 2018 In vitro comparison of the immediate adhesive strength in dentin of three universal adhesive systems. DOI:10.17126/joralres.2018.044 | 2018 | this review only | not stated | not extracted yet |
| Acurio-Benavente 2018 matched by author and year (probable) | NR | this review only | not stated | not extracted yet |
| Ahmed 2020 Quick bonding using a universal adhesive DOI:10.1007/s00784-019-03149-8 | 2019 | this review only | not stated | not extracted yet |
| Ahmed 2020 Quick bonding using a universal adhesive. PMID:31813057 | 2020 | this review only | not stated | not extracted yet |
| Ahn 2015 Effect of additional etching and ethanol-wet bonding on the dentin bond strength of one-step self-etch adhesives. PMID:25671215 | 2015 | this review only | not stated | not extracted yet |
| Ali 2021 Effect of double layer application on bond durability of universal adhesives to proximal dentin-cementum gingival margins. PMID:33940664 | 2021 | this review only | not stated | not extracted yet |
| Atici Bedir 2023 Effect of matrix metalloproteinase inhibitors on bonding durability of universal adhesives DOI:10.4012/dmj.2022-282 | 2023 | this review only | not stated | not extracted yet |
| Balkaya 2023 Evaluation of six different one‐step universal adhesive systems in terms of dentin bond strength, adhesive interface characterization,… DOI:10.1111/jerd.12973 | 2022 | this review only | not stated | not extracted yet |
| Balkaya 2023 Evaluation of six different one-step universal adhesive systems in terms of dentin bond strength, adhesive interface characterization,… PMID:36194081 | 2023 | this review only | not stated | not extracted yet |
| Bedir 2023 Effect of matrix metalloproteinase inhibitors on bonding durability of universal adhesives. PMID:37302822 | 2023 | this review only | not stated | not extracted yet |
| Brkanović 2023 matched by author and year (probable) | NR | this review only | not stated | not extracted yet |
| Brkanović 2023 Comparison of Different Universal Adhesive Systems on Dentin Bond Strength. PMID:36837160 | 2023 | this review only | not stated | not extracted yet |
| Cardoso 2019 Bond Stability of Universal Adhesives Applied To Dentin Using Etch-And-Rinse or Self-Etch Strategies DOI:10.1590/0103-6440201902578 | 2019 | this review only | not stated | not extracted yet |
| Cardoso 2019 Bond Stability of Universal Adhesives Applied To Dentin Using Etch-And-Rinse or Self-Etch Strategies. PMID:31596331 | 2019 | this review only | not stated | not extracted yet |
| Cavalcanti 2023 Effect of irradiance and exposure time on the adhesive properties of universal adhesives after 2 years of storage DOI:10.1007/s00784-023-05142-8 | 2023 | this review only | not stated | not extracted yet |
| Cavalcanti 2023 Effect of irradiance and exposure time on the adhesive properties of universal adhesives after 2 years of storage. PMID:37458867 | 2023 | this review only | not stated | not extracted yet |
| Cetin 2020 Effects of Artificial Aging on the Bond Strengths of Universal Dental Adhesives DOI:10.4103/njcp.njcp_435_19 | 2020 | this review only | not stated | not extracted yet |
| Cetin 2020 Effects of artificial aging on the bond strengths of universal dental adhesives. PMID:32788494 | 2020 | this review only | not stated | not extracted yet |
| Chen 2015 Bonding of universal adhesives to dentine – Old wine in new bottles? DOI:10.1016/j.jdent.2015.03.004 | 2015 | this review only | not stated | not extracted yet |
| Chen 2015 Bonding of universal adhesives to dentine--Old wine in new bottles? PMID:25797702 | 2015 | this review only | not stated | not extracted yet |
| Chen 2021 Effect of air-blowing temperature and water storage time on the bond strength of five universal adhesive systems to dentin DOI:10.4012/dmj.2019-280 | 2021 | this review only | not stated | not extracted yet |
| Chen 2021 Effect of air-blowing temperature and water storage time on the bond strength of five universal adhesive systems to dentin. PMID:32863373 | 2021 | this review only | not stated | not extracted yet |
| Choi 2017 matched by author and year (probable) | NR | this review only | not stated | not extracted yet |
| Choi 2017 Effect of Dentin Wetness on the Bond Strength of Universal Adhesives. PMID:29068404 | 2017 | this review only | not stated | not extracted yet |
| Chowdhury 2019 DOI:10.3290/j.jad.a41986 | NR | this review only | not stated | not extracted yet |
| Chowdhury 2019 matched by author and year (probable) | NR | this review only | not stated | not extracted yet |
| Chowdhury 2019 Effects of Double Application of Contemporary Self-Etch Adhesives on Their Bonding Performance to Dentin with Clinically Relevant Smear… PMID:30799472 | 2019 | this review only | not stated | not extracted yet |
| Chowdhury 2019 Variable Smear Layer and Adhesive Application: The Pursuit of Clinical Relevance in Bond Strength Testing. PMID:31671751 | 2019 | this review only | not stated | not extracted yet |
| Cochinski 2024 Does the absence of HEMA in universal adhesive systems containing MDP affect the bonding properties to enamel and dentine? A one-year… DOI:10.1016/j.ijadhadh.2024.103656 | 2024 | this review only | not stated | not extracted yet |
| Cochinski 2024 matched by author and year (probable) | NR | this review only | not stated | not extracted yet |
| Cuevas-Suarez 2019 DOI:10.3290/j.jad.a41975 | NR | this review only | not stated | not extracted yet |
| Cuevas-Suarez 2019 Bonding Performance of Universal Adhesives: An Updated Systematic Review and Meta-Analysis. PMID:30799468 | 2019 | this review only | not stated | not extracted yet |
| Daneshkazemi 2018 Evaluation of micro shear bonding strength of two universal dentin bondings to superficial dentin by self etch and etch-and-rinse… PMID:30386514 | 2018 | this review only | not stated | not extracted yet |
| De Siqueira 2020 matched by author and year (probable) | NR | this review only | not stated | not extracted yet |
| Demirel 2019 The influence of different etching modes and etching time periods on micro-shear bond strength of multi-mode universal adhesives on dentin DOI:10.5114/jos.2019.87527 | 2019 | this review only | not stated | not extracted yet |
| Demirel 2019 matched by author and year (probable) | NR | this review only | not stated | not extracted yet |
| Donmez 2015 Effect of thermal cycling on micro-tensile bond strength of composite restorations bonded with multimode adhesive DOI:10.1080/01694243.2014.1003180 | 2015 | this review only | not stated | not extracted yet |
| Donmez 2015 matched by author and year (probable) | NR | this review only | not stated | not extracted yet |
| Dutra 2022 Bond strength of two universal adhesive systems to human dentin using different strategies. PMID:36748733 | 2022 | this review only | not stated | not extracted yet |
| Ekrikaya 2023 Dentin bond strength and antimicrobial activities of universal adhesives containing silver nanoparticles synthesized with Rosa canina… DOI:10.1007/s00784-023-05306-6 | 2023 | this review only | not stated | not extracted yet |
| Ekrikaya 2023 Dentin bond strength and antimicrobial activities of universal adhesives containing silver nanoparticles synthesized with Rosa canina… PMID:37821654 | 2023 | this review only | not stated | not extracted yet |
| Ermis 2019 DOI:10.3290/j.jad.a42344 | NR | this review only | not stated | not extracted yet |
| Ermis 2019 Universal Adhesives Benefit from an Extra Hydrophobic Adhesive Layer When Light Cured Beforehand. PMID:30949631 | 2019 | this review only | not stated | not extracted yet |
| Farias 2016 Assessment of the initial and aged dentin bond strength of universal adhesives DOI:10.1016/j.ijadhadh.2016.05.008 | 2016 | this review only | not stated | not extracted yet |
| Farias 2016 matched by author and year (probable) | NR | this review only | not stated | not extracted yet |
| Fathy 2024 Comparative Evaluation of Microtensile Dentin Bond Strength and Interfacial Micromorphology of Three Universal Adhesives DOI:10.1922/ejprd_2706fathy11 | 2024 | this review only | not stated | not extracted yet |
| Fathy 2024 Comparative Evaluation of Microtensile Dentin Bond Strength and Interfacial Micromorphology of Three Universal Adhesives. PMID:39038181 | 2024 | this review only | not stated | not extracted yet |
| Fernandes 2022 Influence of two carbodiimides on the bond strength of universal adhesives to dentin DOI:10.1007/s10266-021-00642-z | 2021 | this review only | not stated | not extracted yet |
| Fernandes 2022 Influence of two carbodiimides on the bond strength of universal adhesives to dentin. PMID:34279762 | 2022 | this review only | not stated | not extracted yet |
| Follak 2021 matched by author and year (probable) | NR | this review only | not stated | not extracted yet |
| Follak 2021 Self-etch Approach of Universal Adhesives as an Alternative to Minimize Bond Degradation on Sound Dentin vs Caries-affected Dentin over… PMID:34060304 | 2021 | this review only | not stated | not extracted yet |
| Fujiwara 2018 Effect of double-layer application on bond quality of adhesive systems DOI:10.1016/j.jmbbm.2017.10.008 | 2018 | this review only | not stated | not extracted yet |
| Fujiwara 2018 Effect of double-layer application on bond quality of adhesive systems. PMID:29040961 | 2018 | this review only | not stated | not extracted yet |
| Garcia 2021 matched by author and year (probable) | NR | this review only | not stated | not extracted yet |
| Hamouda 2022 Effect of dentin moisture and bonding strategies on micro-tensile bond strength using two chemically different universal adhesives DOI:10.21608/asdj.2022.107480.1090 | 2022 | this review only | not stated | not extracted yet |
| Hamouda 2022 matched by author and year (probable) | NR | this review only | not stated | not extracted yet |
| Hardan 2022 matched by author and year (probable) | NR | this review only | not stated | not extracted yet |
| Hardan 2022 Effect of Active Bonding Application after Selective Dentin Etching on the Immediate and Long-Term Bond Strength of Two Universal… PMID:35335459 | 2022 | this review only | not stated | not extracted yet |
| Hasegawa 2021 Degree of conversion and dentin bond strength of light-cured multi-mode adhesives pretreated or mixed with sulfinate agents DOI:10.4012/dmj.2020-346 | 2021 | this review only | not stated | not extracted yet |
| Hasegawa 2021 Degree of conversion and dentin bond strength of light-cured multi-mode adhesives pretreated or mixed with sulfinate agents. PMID:33678732 | 2021 | this review only | not stated | not extracted yet |
| Hatırlı 2022 Effect of Clinically Relevant Smear Layers and pH of Universal Adhesives on Dentin Bond Strength and Durability. PMID:35322946 | 2022 | this review only | not stated | not extracted yet |
| Jacker-Guhr 2019 DOI:10.3290/j.jad.a41974 | NR | this review only | not stated | not extracted yet |
| Jacker-Guhr 2019 How "Universal" is Adhesion? Shear Bond Strength of Multi-mode Adhesives to Enamel and Dentin. PMID:30799475 | 2019 | this review only | not stated | not extracted yet |
| Jafarnia 2022 matched by author and year (probable) | NR | this review only | not stated | not extracted yet |
| Jafarnia 2022 Comparative Evaluation of Microtensile Bond Strength of Three Adhesive Systems. PMID:35937153 | 2022 | this review only | not stated | not extracted yet |
| Jäggi 2024 Shear bond strength of universal adhesives to human enamel and dentin DOI:10.1111/jerd.13204 | 2024 | this review only | not stated | not extracted yet |
| Jäggi 2024 Shear bond strength of universal adhesives to human enamel and dentin. PMID:38308570 | 2024 | this review only | not stated | not extracted yet |
| Karadas 2023 matched by author and year (probable) | NR | this review only | not stated | not extracted yet |
| Karatas 2023 matched by author and year (probable) | NR | this review only | not stated | not extracted yet |
| Karatas 2023 The Effect Of Er,Cr:YSGG Laser Conditioning on Dentin Bond Strength and Nanoleakage of Universal Adhesive Systems: An In Vitro Study. PMID:37879055 | 2023 | this review only | not stated | not extracted yet |
| Khamverdi 2021 Effect of Contamination with Hemostatic Agent on Shear Bond Strength of Composite to Dentin Using G-Premio and Single Bond Universal… DOI:10.18502/fid.v18i27.6937 | 2021 | this review only | not stated | not extracted yet |
| Khamverdi 2021 Effect of Contamination with Hemostatic Agent on Shear Bond Strength of Composite to Dentin Using G-Premio and Single Bond Universal… PMID:35965720 | 2021 | this review only | not stated | not extracted yet |
| Kulkarni 2018 matched by author and year (probable) | NR | this review only | not stated | not extracted yet |
| Kumagai 2020 Moist vs over‐dried etched dentin: FE‐SEM/TEM and bond strength evaluation of resin‐dentin interfaces produced by universal adhesives DOI:10.1111/jerd.12537 | 2019 | this review only | not stated | not extracted yet |
| Kumagai 2020 Moist vs over-dried etched dentin: FE-SEM/TEM and bond strength evaluation of resin-dentin interfaces produced by universal adhesives. PMID:31622014 | 2020 | this review only | not stated | not extracted yet |
| Li 2024 Effect of Simulated Dental Pulpal Pressure Using Fetal Bovine Serum for the Bonding Performance of Contemporary Adhesive to Dentin. PMID:38732688 | 2024 | this review only | not stated | not extracted yet |
| Luque-Martinez 2014 Effects of solvent evaporation time on immediate adhesive properties of universal adhesives to dentin DOI:10.1016/j.dental.2014.07.002 | 2014 | this review only | not stated | not extracted yet |
| Luque-Martinez 2014 Effects of solvent evaporation time on immediate adhesive properties of universal adhesives to dentin. PMID:25139815 | 2014 | this review only | not stated | not extracted yet |
| Maciel Pires 2022 Bonding performance and ultramorphology of the resin-dentine interface of contemporary universal adhesives DOI:10.1007/s00784-022-04402-3 | 2022 | this review only | not stated | not extracted yet |
| Makishi 2016 Effect of Storage Time on Bond Strength and Nanoleakage Expression of Universal Adhesives Bonded to Dentin and Etched Enamel DOI:10.2341/15-163-l | 2016 | this review only | not stated | not extracted yet |
| Makishi 2016 Effect of Storage Time on Bond Strength and Nanoleakage Expression of Universal Adhesives Bonded to Dentin and Etched Enamel. PMID:26666389 | 2016 | this review only | not stated | not extracted yet |
| Meric 2025 Does reducing the acid-etching time increase the micro-tensile bond strength of a bulk fill composite to dentin using different universal… PMID:40114102 | 2025 | this review only | not stated | not extracted yet |
| Moritake 2019 Effect of Active Application on Bond Durability of Universal Adhesives DOI:10.2341/17-384-l | 2019 | this review only | not stated | not extracted yet |
| Moritake 2019 Effect of Active Application on Bond Durability of Universal Adhesives. PMID:30106329 | 2019 | this review only | not stated | not extracted yet |
| Muñoz 2013 Immediate bonding properties of universal adhesives to dentine DOI:10.1016/j.jdent.2013.03.001 | 2013 | this review only | not stated | not extracted yet |
| Muñoz 2013 Immediate bonding properties of universal adhesives to dentine. PMID:23499568 | 2013 | this review only | not stated | not extracted yet |
| Muñoz 2014 Influence of a hydrophobic resin coating on the bonding efficacy of three universal adhesives DOI:10.1016/j.jdent.2014.01.013 | 2014 | this review only | not stated | not extracted yet |
| Muñoz 2014 Influence of a hydrophobic resin coating on the bonding efficacy of three universal adhesives. PMID:24508503 | 2014 | this review only | not stated | not extracted yet |
| Muñoz 2015 In Vitro Longevity of Bonding Properties of Universal Adhesives to Dentin DOI:10.2341/14-055-l | 2015 | this review only | not stated | not extracted yet |
| Muñoz 2015 In vitro longevity of bonding properties of universal adhesives to dentin. PMID:25405904 | 2015 | this review only | not stated | not extracted yet |
| Nonato 2022 Long-term Evaluation of Bonding Performance of Universal Adhesives based on Different Dentinal Moisture Levels. PMID:36346400 | 2022 | this review only | not stated | not extracted yet |
| Ouchi 2020 The Effects of Aluminablasting on Bond Durability Between Universal Adhesives and Tooth Substrate DOI:10.2341/18-170-l | 2020 | this review only | not stated | not extracted yet |
| Ouchi 2020 The Effects of Aluminablasting on Bond Durability Between Universal Adhesives and Tooth Substrate. PMID:31738692 | 2020 | this review only | not stated | not extracted yet |
| Öztürk 2025 Does reducing the acid-etching time increase the micro-tensile bond strength of a bulk fill composite to dentin using different universal… DOI:10.1186/s12903-025-05602-5 | 2025 | this review only | not stated | not extracted yet |
| Pashaev 2017 The effect of double-coating and times on the immediate and 6-month dentin bonding of universal adhesives DOI:10.3233/bme-171665 | 2017 | this review only | not stated | not extracted yet |
| Pashaev 2017 The effect of double-coating and times on the immediate and 6-month dentin bonding of universal adhesives. PMID:28372269 | 2017 | this review only | not stated | not extracted yet |
| Pires 2022 Bonding performance and ultramorphology of the resin-dentine interface of contemporary universal adhesives. PMID:35149904 | 2022 | this review only | not stated | not extracted yet |
| Poggio 2017 Influence of dentin pretreatment on bond strength of universal adhesives DOI:10.1080/23337931.2017.1305273 | 2017 | this review only | not stated | not extracted yet |
| Poggio 2017 Influence of dentin pretreatment on bond strength of universal adhesives. PMID:28642929 | 2017 | this review only | not stated | not extracted yet |
| Saeed 2022 Bonding of universal adhesives to bur-cut dentin: Effect of double application and dentin moisture level DOI:10.4012/dmj.2021-310 | 2022 | this review only | not stated | not extracted yet |
| Saeed 2022 Bonding of universal adhesives to bur-cut dentin: Effect of double application and dentin moisture level. PMID:35676046 | 2022 | this review only | not stated | not extracted yet |
| Sai 2016 Influence of degradation conditions on dentin bonding durability of three universal adhesives DOI:10.1016/j.jdent.2016.09.004 | 2016 | this review only | not stated | not extracted yet |
| Sai 2016 Influence of degradation conditions on dentin bonding durability of three universal adhesives. PMID:27645112 | 2016 | this review only | not stated | not extracted yet |
| Saikaew 2016 The effect of dentine surface preparation and reduced application time of adhesive on bonding strength DOI:10.1016/j.jdent.2016.02.001 | 2016 | this review only | not stated | not extracted yet |
| Saikaew 2016 The effect of dentine surface preparation and reduced application time of adhesive on bonding strength. PMID:26855030 | 2016 | this review only | not stated | not extracted yet |
| Saikaew 2018 Does Shortened Application Time Affect Long-Term Bond Strength of Universal Adhesives to Dentin? DOI:10.2341/17-205-l | 2018 | this review only | not stated | not extracted yet |
| Saikaew 2018 Does Shortened Application Time Affect Long-Term Bond Strength of Universal Adhesives to Dentin? PMID:29630488 | 2018 | this review only | not stated | not extracted yet |
| Saikaew 2019 Effect of air-blowing time and long-term storage on bond strength of universal adhesives to dentin DOI:10.1007/s00784-018-2656-y | 2018 | this review only | not stated | not extracted yet |
| Saikaew 2019 Effect of air-blowing time and long-term storage on bond strength of universal adhesives to dentin. PMID:30327950 | 2019 | this review only | not stated | not extracted yet |
| Saikaew 2021 matched by author and year (probable) | NR | this review only | not stated | not extracted yet |
| Saikaew 2021 Bonding Performance of Self-etching Adhesives to Bur-cut Dentin with Active Application Mode. PMID:34269546 | 2021 | this review only | not stated | not extracted yet |
| Saito 2020 Influence of Application Time on Dentin Bond Performance in Different Etching Modes of Universal Adhesives DOI:10.2341/19-028-l | 2020 | this review only | not stated | not extracted yet |
| Saito 2020 Influence of Application Time on Dentin Bond Performance in Different Etching Modes of Universal Adhesives. PMID:31567054 | 2020 | this review only | not stated | not extracted yet |
| Salem 2021 matched by author and year (probable) | NR | this review only | not stated | not extracted yet |
| Sami 2021 Effect of Different Adhesion Protocols on the Shear Bond Strength of Universal Adhesive Systems to Sound and Artificial Caries-Affected… DOI:10.1055/s-0041-1732776 | 2021 | this review only | not stated | not extracted yet |
| Sami 2021 matched by author and year (probable) | NR | this review only | not stated | not extracted yet |
| Santander-Rengifo 2024 Microtensile Bond Strength and Failure Mode of Different Universal Adhesives on Human Dentin DOI:10.1016/j.identj.2024.04.009 | 2024 | this review only | not stated | not extracted yet |
| Santander-Rengifo 2024 Microtensile Bond Strength and Failure Mode of Different Universal Adhesives on Human Dentin. PMID:38734514 | 2024 | this review only | not stated | not extracted yet |
| Sezinando 2015 Influence of a hydrophobic resin coating on the immediate and 6-month dentin bonding of three universal adhesives DOI:10.1016/j.dental.2015.07.002 | 2015 | this review only | not stated | not extracted yet |
| Sezinando 2015 Influence of a hydrophobic resin coating on the immediate and 6-month dentin bonding of three universal adhesives. PMID:26211697 | 2015 | this review only | not stated | not extracted yet |
| Siqueira 2020 matched by author and year (probable) | NR | this review only | not stated | not extracted yet |
| Takamizawa 2016 Influence of different etching modes on bond strength and fatigue strength to dentin using universal adhesive systems DOI:10.1016/j.dental.2015.11.005 | 2016 | this review only | not stated | not extracted yet |
| Takamizawa 2016 Influence of different etching modes on bond strength and fatigue strength to dentin using universal adhesive systems. PMID:26719131 | 2016 | this review only | not stated | not extracted yet |
| Tamura 2017 Influence of air-powder polishing on bond strength and surface-free energy of universal adhesive systems DOI:10.4012/dmj.2016-185 | 2017 | this review only | not stated | not extracted yet |
| Tamura 2017 Influence of air-powder polishing on bond strength and surface-free energy of universal adhesive systems. PMID:28701636 | 2017 | this review only | not stated | not extracted yet |
| Tang 2023 Adhesive Performance Assessment of Universal Adhesives and Universal Adhesive/Composite Cement Combinations. PMID:37975313 | 2023 | this review only | not stated | not extracted yet |
| Tekçe 2016 Do matrix metalloproteinase inhibitors improve the bond durability of universal dental adhesives? DOI:10.1002/sca.21293 | 2016 | this review only | not stated | not extracted yet |
| Tekçe 2016 Do matrix metalloproteinase inhibitors improve the bond durability of universal dental adhesives? PMID:26763084 | 2016 | this review only | not stated | not extracted yet |
| Tonga 2025 matched by author and year (probable) | NR | this review only | not stated | not extracted yet |
| Tonga 2025 Effect of double-layer application techniques on the dentin micro-tensile bond strength of universal adhesives. PMID:40696338 | 2025 | this review only | not stated | not extracted yet |
| Tsujimoto 2019 Influence of surface wetness on bonding effectiveness of universal adhesives in etch‐and‐rinse mode DOI:10.1111/eos.12596 | 2018 | this review only | not stated | not extracted yet |
| Tsujimoto 2019 Influence of surface wetness on bonding effectiveness of universal adhesives in etch-and-rinse mode. PMID:30536451 | 2019 | this review only | not stated | not extracted yet |
| Tsujimoto 2022 matched by author and year (probable) | NR | this review only | not stated | not extracted yet |
| Tsujimoto 2022 Bond Durability of Two-Step HEMA-Free Universal Adhesive. PMID:36135569 | 2022 | this review only | not stated | not extracted yet |
| Ugurlu 2020 Effect of the double application of universal adhesives on the dentine bond strength after radiotherapy DOI:10.1111/adj.12744 | 2020 | this review only | not stated | not extracted yet |
| Ugurlu 2020 Effect of the double application of universal adhesives on the dentine bond strength after radiotherapy. PMID:31900933 | 2020 | this review only | not stated | not extracted yet |
| Vermelho 2017 Adhesion of multimode adhesives to enamel and dentin after one year of water storage DOI:10.1007/s00784-016-1966-1 | 2016 | this review only | not stated | not extracted yet |
| Vermelho 2017 Adhesion of multimode adhesives to enamel and dentin after one year of water storage. PMID:27714528 | 2017 | this review only | not stated | not extracted yet |
| Wagner 2014 Bonding performance of universal adhesives in different etching modes DOI:10.1016/j.jdent.2014.04.012 | 2014 | this review only | not stated | not extracted yet |
| Wagner 2014 Bonding performance of universal adhesives in different etching modes. PMID:24814138 | 2014 | this review only | not stated | not extracted yet |
| Wang 2023 The effect of an extra hydrophobic resin layer on the bond strength and durability of one-step universal adhesives used as a primer DOI:10.1016/j.jdent.2023.104568 | 2023 | this review only | not stated | not extracted yet |
| Wang 2023 The effect of an extra hydrophobic resin layer on the bond strength and durability of one-step universal adhesives used as a primer. PMID:37308054 | 2023 | this review only | not stated | not extracted yet |
| Wendlinger 2023 Are universal adhesives in etch-and-rinse mode better than old 2-step etch-and-rinse adhesives? One-year evaluation of bonding properties… DOI:10.1016/j.jdent.2023.104481 | 2023 | this review only | not stated | not extracted yet |
| Wendlinger 2023 Effect of the Absence of HEMA on the Bonding Properties of Universal Adhesive Systems Containing 10-MDP: An In Vitro Study DOI:10.2341/22-050-l | 2023 | this review only | not stated | not extracted yet |
| Wendlinger 2023 Are universal adhesives in etch-and-rinse mode better than old 2-step etch-and-rinse adhesives? One-year evaluation of bonding properties… PMID:36918052 | 2023 | this review only | not stated | not extracted yet |
| Wendlinger 2023 Effect of the Absence of HEMA on the Bonding Properties of Universal Adhesive Systems Containing 10-MDP: An In Vitro Study. PMID:37503689 | 2023 | this review only | not stated | not extracted yet |
| Yamauchi 2019 Etch-and-rinse vs self-etch mode for dentin bonding effectiveness of universal adhesives DOI:10.2334/josnusd.18-0433 | 2019 | this review only | not stated | not extracted yet |
| Yamauchi 2019 Etch-and-rinse vs self-etch mode for dentin bonding effectiveness of universal adhesives. PMID:31631096 | 2019 | this review only | not stated | not extracted yet |
| Yokoyama 2021 DOI:10.3290/j.jad.b2000257 | NR | this review only | not stated | not extracted yet |
| Yokoyama 2021 Influence of Different Application Methods on the Bonding Effectiveness of Universal Adhesives to Dentin in the Early Phase. PMID:34549928 | 2021 | this review only | not stated | not extracted yet |
Overlap with other reviews
Reviews that include the same primary studies are not independent evidence. Shared counts match studies by PMID, DOI or NCT, and otherwise by author and year (a probable match). Only the non-Cochrane dental reviews have study lists, so overlap with Cochrane reviews is not counted yet.
| Review | Shared studies | Jaccard |
|---|---|---|
| Bonding of Glass-Ionomer Cement and Adhesives to Silver Diamine Fluoride-treated Dentin: An Updated Systematic Review and Meta-Analysis. (2022) | 2 | 0.01 |
Review question
| Element | Planned (methods) | Found (results) |
|---|---|---|
| Population | Sound permanent human teeth in laboratory studies (human or bovine dentin) | Sound human/bovine dentin specimens (n=82 studies; 22 universal adhesives) |
| Intervention | Application of different universal adhesives on dentin (self-etch or etch-and-rinse mode) | 22 universal adhesives in self-etch and etch-and-rinse modes |
| Comparison | Standard adhesive (Scotchbond Universal) or comparisons among adhesives | Scotchbond Universal (reference) |
| Outcomes | Dentin bond strength (MPa; microtensile, microshear or shear) before and after ageing | Dentin bond strength, MD in MPa vs SBU (network of 77, 46, 46 and 24 studies across four analyses) |
| Study designs | In vitro studies including Scotchbond Universal as control | In vitro studies (82) |
| Timing | Before ageing (24 h or 1 week) and after ageing | Before and after ageing |