Non-Cochrane · aetiology · PM42001496
Influence of periodontal conditions on quality of life in patients with chronic kidney disease: A systematic review and meta-analysis.
Schöffer C, Del'Agnese C-C, Marder E-L, et al. · Medicina oral, patologia oral y cirugia bucal · 2026 · PubMed · doi:10.4317/medoral.28048
Findings
10 findings
| Population | ||||
|---|---|---|---|---|
| Systemically healthy individuals (control sample) | ESRD | Systemically healthy controls | OHIP-14 total score (0-56) Sample = Healthy | Pooled mean 5.59 [-2.39, 13.57] GRADE not reported 2 studies · 346 participants |
| ESRD and healthy samples combined | ESRD | Systemically healthy controls | OHIP-14 total score (0-56) Overall (ESRD and healthy) | Pooled mean 10.8 [4.1, 17.49] GRADE not reported 6 studies · 1566 participants |
| Adults with end-stage renal disease on hemodialysis (ESRD sample) | ESRD (hemodialysis, one study also transplant recipients) | Systemically healthy controls | OHIP-14 total score (0-56) Sample = ESRD | Pooled mean 12.29 [4.07, 20.52] GRADE not reported 6 studies · 1220 participants |
| Adults with end-stage renal disease (ESRD) on hemodialysis or after kidney transplantation | ESRD (hemodialysis or transplantation) | Systemically healthy controls | Periodontitis prevalence (%) Dialysis and transplant clinics · ESRD sample | Prevalence (%) 84.2 [56.4, 95.6] GRADE not reported 3 studies · 818 participants |
| ESRD and healthy samples combined | ESRD | Healthy controls | Periodontitis prevalence (%) Overall (ESRD and healthy) | Pooled prevalence (%) 77.4 [52.5, 91.4] GRADE not reported 3 studies · 1164 participants |
| Systemically healthy individuals (control sample) | ESRD | Healthy controls | Periodontitis prevalence (%) Sample = Healthy | Pooled prevalence (%) 59.7 [19.4, 90.1] GRADE not reported 2 studies · 346 participants |
| Adults with end-stage renal disease on hemodialysis (and one transplant group) | Stage III/IV periodontitis | No periodontitis or stage I/II periodontitis | OHIP-14 total score | MD 1.88 [0.67, 3.09] Very low 2 studies · 224 participants |
| Adults with end-stage renal disease on hemodialysis | Higher periodontal probing depth | Lower periodontal probing depth (correlation) | OHIP-14 score | Correlation r 0.145 [0.016, 0.273] Very low 2 studies · 237 participants |
| Adults with end-stage renal disease on hemodialysis | Higher plaque index | Lower plaque index (correlation) | OHIP-14 score | Correlation r 0.385 [0.241, 0.529] Very low 2 studies · 192 participants |
| Adults with end-stage renal disease on hemodialysis | Higher plaque index | Lower plaque index (correlation) | GOHAI score | Correlation r 0.395 [0.251, 0.539] GRADE not reported 2 studies · 192 participants |
Included primary studies 13
Open in Studies| Study | Year | Also included by | Outcomes it informs here | Trial data |
|---|---|---|---|---|
| Oliveira 2020 Periodontitis is associated with oral health‐related quality of life in individuals with end‐stage renal disease DOI:10.1111/jcpe.13233 | 2020 | 1 other review | not stated | not extracted yet |
| Guzeldemir 2009 Oral Health–Related Quality of Life and Periodontal Health Status in Patients Undergoing Hemodialysis DOI:10.14219/jada.archive.2009.0052 | 2009 | this review only | not stated | not extracted yet |
| Guzeldemir 2009 Oral health-related quality of life and periodontal health status in patients undergoing hemodialysis. PMID:19797559 | 2009 | this review only | not stated | not extracted yet |
| Hajian-Tilaki 2014 Oral Health-related Quality of Life and Periodontal and Dental Health Status in Iranian Hemodialysis Patients DOI:10.5005/jp-journals-10024-1566 | 2014 | this review only | not stated | not extracted yet |
| Hajian-Tilaki 2014 Oral health-related quality of life and periodontal and dental health status in Iranian hemodialysis patients. PMID:25576117 | 2014 | this review only | not stated | not extracted yet |
| Kahar 2019 Assessment of the Effect of Oral Health on Quality of Life and Oral-Health Indicators among ESRD Patients in Southwest Florida: A Pilot… DOI:10.1155/2019/1608329 | 2019 | this review only | not stated | not extracted yet |
| Kahar 2019 Assessment of the Effect of Oral Health on Quality of Life and Oral-Health Indicators among ESRD Patients in Southwest Florida: A Pilot… PMID:31662758 | 2019 | this review only | not stated | not extracted yet |
| Oliveira 2020 Periodontitis is associated with oral health-related quality of life in individuals with end-stage renal disease. PMID:31834630 | 2020 | this review only | not stated | not extracted yet |
| Pakpour 2015 A case-control study on oral health-related quality of life in kidney disease patients undergoing haemodialysis DOI:10.1007/s00784-014-1355-6 | 2014 | this review only | not stated | not extracted yet |
| Pakpour 2015 A case-control study on oral health-related quality of life in kidney disease patients undergoing haemodialysis. PMID:25395347 | 2015 | this review only | not stated | not extracted yet |
| Schmalz 2016 <i><scp>IRAK</scp>1</i> variant is protective for orthodontic‐induced external apical root resorption DOI:10.1111/odi.12514 | 2016 | this review only | not stated | not extracted yet |
| Schmalz 2016 Oral health-related quality of life in patients on chronic haemodialysis and after kidney transplantation. PMID:27265431 | 2016 | this review only | not stated | not extracted yet |
| Schmalz 2018 Dialysis vintage time has the strongest correlation to psychosocial pattern of oral health-related quality of life - a multicentre… PMID:30341269 | 2018 | this review only | not stated | not extracted yet |
Overlap with other reviews
Reviews that include the same primary studies are not independent evidence. Shared counts match studies by PMID, DOI or NCT, and otherwise by author and year (a probable match). Only the non-Cochrane dental reviews have study lists, so overlap with Cochrane reviews is not counted yet.
| Review | Shared studies | Jaccard |
|---|---|---|
| Association between periodontitis and oral health-related quality of life in patients with systemic conditions: A meta-analysis. (2026) | 1 | 0.03 |
Review question
| Element | Planned (methods) | Found (results) |
|---|---|---|
| Population | Adults (>=18 years) with chronic kidney disease | Adults with end-stage renal disease on hemodialysis (n=6 studies), one also with kidney transplant recipients and healthy controls |
| Intervention | Periodontitis or severe periodontitis defined by clinical periodontal examination (CAL and/or PPD); clinical periodontal parameters | Stage III/IV periodontitis; probing depth; plaque index; ESRD versus healthy |
| Comparison | No periodontitis or initial or moderate periodontitis | No periodontitis or stage I/II periodontitis; healthy controls |
| Outcomes | OHRQoL measured with validated instruments | OHIP-14 (n=7 studies); GOHAI (n=3 studies); periodontitis prevalence (n=3 studies) |
| Study designs | Observational studies (longitudinal, case-control, cross-sectional) | Six cross-sectional studies and one case-control study (n=7) |
| Timing | Not specified | Not specified |