Non-Cochrane · intervention · PM41921983
Clinical outcomes of tooth autotransplantation: a systematic review and meta-analysis of survival.
Wong Jasmine, Fok Elise Hoi Wan, Li Kar Yan, et al. · Restorative dentistry & endodontics · 2026 · PubMed · doi:10.5395/rde.2026.51.e17
Findings
21 findings
| Population | ||||
|---|---|---|---|---|
| Patients with autotransplanted permanent teeth | Tooth autotransplantation | None (single-arm pooled proportion) | Tooth survival (proportion of autotransplanted teeth present at follow-up) Long-term (>8 years) · Overall | Proportion (survival rate, %) 84.80 [76.70, 92.91] GRADE not reported 14 studies |
| Patients with autotransplanted permanent teeth | Tooth autotransplantation | None (single-arm pooled proportion) | Tooth survival (proportion of autotransplanted teeth present at follow-up) Short-term (1 to <=4 years) · Overall | Proportion (survival rate, %) 96.31 [94.80, 97.82] GRADE not reported 20 studies |
| Patients with autotransplanted permanent teeth | Tooth autotransplantation | None (single-arm pooled proportion) | Tooth survival (proportion of autotransplanted teeth present at follow-up) Medium-term (>4 to <=8 years) · Overall | Proportion (survival rate, %) 88.23 [85.59, 90.87] GRADE not reported 12 studies |
| Patients aged 18 years or younger with autotransplanted teeth | Tooth autotransplantation | None (single-arm pooled proportion) | Tooth survival (proportion of autotransplanted teeth present at follow-up) Long-term (>8 years) · Age <=18 years | Proportion (survival rate, %) 89.77 [83.37, 96.17] GRADE not reported 8 studies |
| Patients aged 18 years or younger with autotransplanted teeth | Tooth autotransplantation | None (single-arm pooled proportion) | Tooth survival (proportion of autotransplanted teeth present at follow-up) Medium-term (>4 to <=8 years) · Age <=18 years | Proportion (survival rate, %) 87.56 [84.74, 90.38] GRADE not reported 5 studies |
| Patients aged 18 years or younger with autotransplanted teeth | Tooth autotransplantation | None (single-arm pooled proportion) | Tooth survival (proportion of autotransplanted teeth present at follow-up) Short-term (1 to <=4 years) · Age <=18 years | Proportion (survival rate, %) 96.92 [94.79, 99.05] GRADE not reported 9 studies |
| Patients older than 18 years with autotransplanted teeth | Tooth autotransplantation | None (single-arm pooled proportion) | Tooth survival (proportion of autotransplanted teeth present at follow-up) Short-term (1 to <=4 years) · Age >18 years | Proportion (survival rate, %) 95.92 [93.40, 98.44] GRADE not reported 7 studies |
| Patients older than 18 years with autotransplanted teeth | Tooth autotransplantation | None (single-arm pooled proportion) | Tooth survival (proportion of autotransplanted teeth present at follow-up) Medium-term (>4 to <=8 years) · Age >18 years | Proportion (survival rate, %) 88.94 [84.62, 93.25] GRADE not reported 7 studies |
| Patients older than 18 years with autotransplanted teeth | Tooth autotransplantation | None (single-arm pooled proportion) | Tooth survival (proportion of autotransplanted teeth present at follow-up) Long-term (>8 years) · Age >18 years | Proportion (survival rate, %) 82.20 [69.97, 94.44] GRADE not reported 4 studies |
| Patients with autotransplanted teeth with completed root development | Tooth autotransplantation | None (single-arm pooled proportion) | Tooth survival (proportion of autotransplanted teeth present at follow-up) Medium-term (>4 to <=8 years) · Root development: all donor teeth completed | Proportion (survival rate, %) 92.14 [89.10, 95.18] GRADE not reported 3 studies |
| Patients with autotransplanted teeth with completed root development | Tooth autotransplantation | None (single-arm pooled proportion) | Tooth survival (proportion of autotransplanted teeth present at follow-up) Short-term (1 to <=4 years) · Root development: all donor teeth completed | Proportion (survival rate, %) 91.38 [85.29, 97.47] GRADE not reported 5 studies |
| Patients with autotransplanted teeth with completed root development | Tooth autotransplantation | None (single-arm pooled proportion) | Tooth survival (proportion of autotransplanted teeth present at follow-up) Long-term (>8 years) · Root development: all donor teeth completed | Proportion (survival rate, %) 85.30 [73.78, 96.81] GRADE not reported 4 studies |
| Patients with autotransplanted teeth with incomplete root development | Tooth autotransplantation | None (single-arm pooled proportion) | Tooth survival (proportion of autotransplanted teeth present at follow-up) Medium-term (>4 to <=8 years) · Root development: all donor teeth incomplete | Proportion (survival rate, %) 88.59 [83.76, 93.43] GRADE not reported 2 studies |
| Patients with autotransplanted teeth with incomplete root development | Tooth autotransplantation | None (single-arm pooled proportion) | Tooth survival (proportion of autotransplanted teeth present at follow-up) Long-term (>8 years) · Root development: all donor teeth incomplete | Proportion (survival rate, %) 96.39 [92.77, 100.00] GRADE not reported 3 studies |
| Patients with autotransplanted teeth with incomplete root development | Tooth autotransplantation | None (single-arm pooled proportion) | Tooth survival (proportion of autotransplanted teeth present at follow-up) Short-term (1 to <=4 years) · Root development: all donor teeth incomplete | Proportion (survival rate, %) 99.50 [98.31, 100.70] GRADE not reported 3 studies |
| Patients with autotransplanted teeth, by age | Tooth autotransplantation | Age >18 years | Tooth survival (proportion of autotransplanted teeth present at follow-up) Long-term (>8 years) · Age <=18 years vs >18 years | Proportion difference (percentage points) 7.40 [-6.34, 21.13] GRADE not reported 12 studies |
| Patients with autotransplanted teeth, by age | Tooth autotransplantation | Age >18 years | Tooth survival (proportion of autotransplanted teeth present at follow-up) Medium-term (>4 to <=8 years) · Age <=18 years vs >18 years | Proportion difference (percentage points) -1.59 [-7.80, 4.36] GRADE not reported 12 studies |
| Patients with autotransplanted teeth, by age | Tooth autotransplantation | Age >18 years | Tooth survival (proportion of autotransplanted teeth present at follow-up) Short-term (1 to <=4 years) · Age <=18 years vs >18 years | Proportion difference (percentage points) 0.96 [-3.32, 5.25] GRADE not reported 16 studies |
| Patients with autotransplanted teeth, by root development | Tooth autotransplantation | Incomplete root development | Tooth survival (proportion of autotransplanted teeth present at follow-up) Short-term (1 to <=4 years) · Completed vs incomplete root development | Proportion difference (percentage points) -5.25 [-13.23, 2.73] GRADE not reported 8 studies |
| Patients with autotransplanted teeth, by root development | Tooth autotransplantation | Incomplete root development | Tooth survival (proportion of autotransplanted teeth present at follow-up) Medium-term (>4 to <=8 years) · Completed vs incomplete root development | Proportion difference (percentage points) 3.55 [-5.73, 12.82] GRADE not reported 5 studies |
| Patients with autotransplanted teeth, by root development | Tooth autotransplantation | Incomplete root development | Tooth survival (proportion of autotransplanted teeth present at follow-up) Long-term (>8 years) · Completed vs incomplete root development | Proportion difference (percentage points) -7.09 [-23.17, 8.99] GRADE not reported 7 studies |
Included primary studies 46
Open in Studies| Study | Year | Also included by | Outcomes it informs here | Trial data |
|---|---|---|---|---|
| Arikan 2008 5-year longitudinal study of survival rate and periodontal parameter changes at sites of maxillary canine autotransplantation. PMID:18380551 | 2008 | 1 other review | Tooth survival (proportion of autotransplanted teeth present at follow-up) | not extracted yet |
| Barendregt 2023 An evaluation of 1654 premolars transplanted in the posterior region-A retrospective analysis of survival, success and complications. PMID:37114739 | 2023 | 1 other review | Tooth survival (proportion of autotransplanted teeth present at follow-up) | not extracted yet |
| Cui 2021 Effect of Root Canal Therapy on the Success Rate of Teeth with Complete Roots in Autogenous Tooth Transplantation. PMID:33936357 | 2021 | 1 other review | Tooth survival (proportion of autotransplanted teeth present at follow-up) | not extracted yet |
| de Carvalho 2014 Statistical analysis of teeth autotransplantation in Portugal's region of Chaves. PMID:24444258 | 2014 | 1 other review | Tooth survival (proportion of autotransplanted teeth present at follow-up) | not extracted yet |
| de Freitas Coutinho 2021 Success, Survival Rate, and Soft Tissue Esthetic of Tooth Autotransplantation. PMID:33245974 | 2021 | 1 other review | Tooth survival (proportion of autotransplanted teeth present at follow-up) | not extracted yet |
| EzEldeen 2019 Use of CBCT Guidance for Tooth Autotransplantation in Children. PMID:30786806 | 2019 | 1 other review | Tooth survival (proportion of autotransplanted teeth present at follow-up) | not extracted yet |
| Han 2025 Efficacy of root canal treatment for autotransplanted third molars: a 6-Year cohort study of 167 teeth in southern China. PMID:39802186 | 2025 | 1 other review | Tooth survival (proportion of autotransplanted teeth present at follow-up) | not extracted yet |
| Jang 2016 Prognostic Factors for Clinical Outcomes in Autotransplantation of Teeth with Complete Root Formation: Survival Analysis for up to 12 Years. PMID:26686824 | 2016 | 1 other review | Tooth survival (proportion of autotransplanted teeth present at follow-up) | not extracted yet |
| Louropoulou 2024 An evaluation of 910 premolars transplanted in the anterior region-A retrospective analysis of survival, success, and complications. PMID:37731296 | 2024 | 1 other review | not stated | not extracted yet |
| Lucas-Taulé 2021 Mid-term outcomes and periodontal prognostic factors of autotransplanted third molars: A retrospective cohort study. PMID:33764523 | 2021 | 1 other review | Tooth survival (proportion of autotransplanted teeth present at follow-up) | not extracted yet |
| Mertens 2016 Long-term follow up of post-surgical tooth autotransplantation: a retrospective study. PMID:25329745 | 2016 | 1 other review | Tooth survival (proportion of autotransplanted teeth present at follow-up) | not extracted yet |
| Raabe 2021 A retrospective analysis of autotransplanted teeth including an evaluation of a novel surgical technique. PMID:33263141 | 2021 | 1 other review | Tooth survival (proportion of autotransplanted teeth present at follow-up) | not extracted yet |
| Strbac 2017 Survival rate of autotransplanted teeth after 5 years - A retrospective cohort study. PMID:28554537 | 2017 | 1 other review | Tooth survival (proportion of autotransplanted teeth present at follow-up) | not extracted yet |
| van Westerveld 2019 Long-term outcomes 1-20 years after autotransplantation of teeth: clinical and radiographic evaluation of 66 premolars and 8 molars. PMID:31239226 | 2019 | 1 other review | Tooth survival (proportion of autotransplanted teeth present at follow-up) | not extracted yet |
| Verweij 2016 Success and survival of autotransplanted premolars and molars during short-term clinical follow-up. PMID:26661032 | 2016 | 1 other review | Tooth survival (proportion of autotransplanted teeth present at follow-up) | not extracted yet |
| Watanabe 2010 Long-term observation of autotransplanted teeth with complete root formation in orthodontic patients. PMID:21130330 | 2010 | 1 other review | Tooth survival (proportion of autotransplanted teeth present at follow-up) | not extracted yet |
| Xia 2025 Prognostic factors for autotransplanted third molars with completely formed roots: A retrospective cohort study. PMID:39580736 | 2025 | 1 other review | Tooth survival (proportion of autotransplanted teeth present at follow-up) | not extracted yet |
| Yan 2010 Immediate autotransplantation of mandibular third molar in China. PMID:20452259 | 2010 | 1 other review | Tooth survival (proportion of autotransplanted teeth present at follow-up) | not extracted yet |
| Yu 2017 Autotransplantation of third molars with completely formed roots into surgically created sockets and fresh extraction sockets: a 10-year… PMID:28062250 | 2017 | 1 other review | Tooth survival (proportion of autotransplanted teeth present at follow-up) | not extracted yet |
| Abela 2019 Survival probability of dental autotransplantation of 366 teeth over 34 years within a hospital setting in the United Kingdom. PMID:31144709 | 2019 | this review only | Tooth survival (proportion of autotransplanted teeth present at follow-up) | not extracted yet |
| Ainiwaer 2024 Midterm outcomes of autogenous mature third molars transplantation into surgically created sockets: A retrospective cohort study. PMID:38641921 | 2024 | this review only | Tooth survival (proportion of autotransplanted teeth present at follow-up) | not extracted yet |
| Akhlef 2025 Autotransplantation of Premolars to the Anterior Maxilla: A Long-Term Retrospective Cohort Study of Survival, Success, Esthetic, and… PMID:39663542 | 2025 | this review only | Tooth survival (proportion of autotransplanted teeth present at follow-up) | not extracted yet |
| Albalooshy 2023 The outcomes of auto-transplanted premolars in the anterior maxilla following traumatic dental injuries. PMID:36740836 | 2023 | this review only | Tooth survival (proportion of autotransplanted teeth present at follow-up) | not extracted yet |
| Andreasen 1990 A long-term study of 370 autotransplanted premolars. Part II. Tooth survival and pulp healing subsequent to transplantation. PMID:2318259 | 1990 | this review only | not stated | not extracted yet |
| Bauss 2004 Influence of orthodontic derotation and extrusion on pulpal and periodontal condition of autotransplanted immature third molars. PMID:15067266 | 2004 | this review only | Tooth survival (proportion of autotransplanted teeth present at follow-up) | not extracted yet |
| Boschini 2020 Long term survival of mature autotransplanted teeth: A retrospective single center analysis. PMID:32389731 | 2020 | this review only | Tooth survival (proportion of autotransplanted teeth present at follow-up) | not extracted yet |
| Czochrowska 2002 Outcome of tooth transplantation: survival and success rates 17-41 years posttreatment. PMID:11840123 | 2002 | this review only | Tooth survival (proportion of autotransplanted teeth present at follow-up) | not extracted yet |
| Denys 2013 Importance of root development in autotransplantations: a retrospective study of 137 teeth with a follow-up period varying from 1 week to… PMID:23407475 | 2013 | this review only | Tooth survival (proportion of autotransplanted teeth present at follow-up) | not extracted yet |
| Gilijamse 2016 Tooth autotransplantation in the anterior maxilla and mandible: retrospective results in young patients. PMID:27492566 | 2016 | this review only | Tooth survival (proportion of autotransplanted teeth present at follow-up) | not extracted yet |
| Grisar 2019 Long-term outcome of autogenously transplanted maxillary canines. PMID:30847235 | 2019 | this review only | Tooth survival (proportion of autotransplanted teeth present at follow-up) | not extracted yet |
| Huth 2013 Autotransplantation and surgical uprighting of impacted or retained teeth: A retrospective clinical study and evaluation of patient… PMID:23638808 | 2013 | this review only | Tooth survival (proportion of autotransplanted teeth present at follow-up) | not extracted yet |
| Jonsson 2024 Long-term survival of 57 premolars consecutively transplanted to premolar sites. PMID:39093250 | 2024 | this review only | Tooth survival (proportion of autotransplanted teeth present at follow-up) | not extracted yet |
| Josefsson 1999 Treatment of lower second premolar agenesis by autotransplantation: four-year evaluation of eighty patients. PMID:10445365 | 1999 | this review only | Tooth survival (proportion of autotransplanted teeth present at follow-up) | not extracted yet |
| Kafourou 2017 Outcomes and prognostic factors that influence the success of tooth autotransplantation in children and adolescents. PMID:28612428 | 2017 | this review only | Tooth survival (proportion of autotransplanted teeth present at follow-up) | not extracted yet |
| Kokai 2015 Retrospective study of 100 autotransplanted teeth with complete root formation and subsequent orthodontic treatment. PMID:26672704 | 2015 | this review only | Tooth survival (proportion of autotransplanted teeth present at follow-up) | not extracted yet |
| Kvint 2010 Autotransplantation of teeth in 215 patients. A follow-up study. PMID:20050735 | 2010 | this review only | Tooth survival (proportion of autotransplanted teeth present at follow-up) | not extracted yet |
| Li 2025 Fully guided system for position-predictable autotransplantation of teeth: A randomized clinical trial. PMID:39869072 | 2025 | this review only | Tooth survival (proportion of autotransplanted teeth present at follow-up) | not extracted yet |
| Liao 2023 Effectiveness evaluation of autotransplanted teeth after performing extraoral endodontic surgery instead of conventional root canal therapy. PMID:38097962 | 2023 | this review only | Tooth survival (proportion of autotransplanted teeth present at follow-up) | not extracted yet |
| Lin 2020 Endodontic considerations of survival rate for autotransplanted third molars: a nationwide population-based study. PMID:32009248 | 2020 | this review only | Tooth survival (proportion of autotransplanted teeth present at follow-up) | not extracted yet |
| Myrlund 2004 Root length in transplanted premolars. PMID:15370631 | 2004 | this review only | Tooth survival (proportion of autotransplanted teeth present at follow-up) | not extracted yet |
| Plakwicz 2013 Survival and success rates of autotransplanted premolars: a prospective study of the protocol for developing teeth. PMID:23910204 | 2013 | this review only | Tooth survival (proportion of autotransplanted teeth present at follow-up) | not extracted yet |
| Restrepo-Restrepo 2024 Retrospective Follow-up Assessment of Risk Variables Influencing the Outcome of Autologous Tooth Transplantation. PMID:38442852 | 2024 | this review only | not stated | not extracted yet |
| Sugai 2010 Clinical study on prognostic factors for autotransplantation of teeth with complete root formation. PMID:20630706 | 2010 | this review only | Tooth survival (proportion of autotransplanted teeth present at follow-up) | not extracted yet |
| Vilhjálmsson 2011 Dental auto-transplantation to anterior maxillary sites. PMID:21143392 | 2011 | this review only | Tooth survival (proportion of autotransplanted teeth present at follow-up) | not extracted yet |
| Yang 2019 Outcomes of autotransplanted teeth and prognostic factors: a 10-year retrospective study. PMID:29525925 | 2019 | this review only | Tooth survival (proportion of autotransplanted teeth present at follow-up) | not extracted yet |
| Yoshino 2012 A retrospective survey of autotransplantation of teeth in dental clinics. PMID:21793869 | 2012 | this review only | Tooth survival (proportion of autotransplanted teeth present at follow-up) | not extracted yet |
Overlap with other reviews
Reviews that include the same primary studies are not independent evidence. Shared counts match studies by PMID, DOI or NCT, and otherwise by author and year (a probable match). Only the non-Cochrane dental reviews have study lists, so overlap with Cochrane reviews is not counted yet.
Review question
| Element | Planned (methods) | Found (results) |
|---|---|---|
| Population | Patients with permanent dentition undergoing tooth autotransplantation; humans | Patients receiving autotransplanted teeth; mean age 10 to 39 years (n=46 studies) |
| Intervention | Tooth autotransplantation (intentional replantation excluded) | Tooth autotransplantation of third molars, premolars, molars, canines and incisors (n=46 studies) |
| Comparison | Not specified (single-arm; short-, medium- and long-term follow-up and subgroups by age and root development) | Not specified (single-arm pooled proportions) |
| Outcomes | Survival rate (proportion of autotransplanted teeth present at follow-up); reasons for extraction; patient-reported outcome measures | Pooled survival rate (short-term n=20 studies; medium-term n=12; long-term n=14); reasons for extraction (259 teeth); PROMs (8 studies) |
| Study designs | Clinical studies in humans with clearly defined clinical/radiographic outcome criteria; case reports/series excluded; English language | Mostly observational studies; risk of bias moderate (n=21) to serious (n=20) by ROBINS-I V2 |
| Timing | Follow-up of at least 1 year; short-term 1 to <=4 years, medium-term >4 to <=8 years, long-term >8 years | Average follow-up 1 to 26.4 years; short-term n=20, medium-term n=12, long-term n=14 |