Non-Cochrane · DTA · PM41906136

Diagnostic accuracy of the Fonseca anamnestic index for temporomandibular disorders: a systematic review and meta-analysis.

Ma Feihong, Wang Yayuan, Han Dan, et al. · Head & face medicine · 2026 · PubMed · doi:10.1186/s13005-026-00601-5

Findings

21 findings

Population
Patients suspected or confirmed with temporomandibular disorders (TMD)Fonseca Anamnestic Index (FAI) screening questionnaire (index test)Reference standard diagnosis (DC/TMD or RDC/TMD with imaging)Diagnostic odds ratio
Not specified
DOR 26.51 [11.66, 60.23]
GRADE not reported
9 studies · 2381 participants
Patients suspected of or diagnosed with temporomandibular disorders (TMD)Fonseca Anamnestic Index (FAI or short-form SFAI) questionnaireReference standard (DC/TMD or RDC/TMD with clinical, imaging or arthroscopic examination)Negative likelihood ratio of FAI for TMD
Value plotted in Fig. 6 forest plot
Negative likelihood ratio 0.14 [0.08, 0.23]
GRADE not reported
9 studies · 2381 participants
Patients suspected or confirmed with temporomandibular disorders (TMD)Fonseca Anamnestic Index (FAI) screening questionnaire (index test)Reference standard diagnosis (DC/TMD or RDC/TMD with imaging)Pooled sensitivity
Not specified · Subgroup: Chinese population
Sensitivity 0.95 [0.86, 1.00]
GRADE not reported
1 study · 923 participants
Patients suspected or confirmed with temporomandibular disorders (TMD)Fonseca Anamnestic Index (FAI) screening questionnaire (index test)Reference standard diagnosis (DC/TMD or RDC/TMD with imaging)Pooled sensitivity
Not specified · Subgroup: Non-Chinese populations
Sensitivity 0.88 [0.82, 0.95]
GRADE not reported
8 studies · 1458 participants
Patients suspected or confirmed with temporomandibular disorders (TMD)Fonseca Anamnestic Index (FAI) screening questionnaire (index test)Reference standard diagnosis (DC/TMD or RDC/TMD with imaging)Pooled sensitivity
Not specified · Subgroup: Sample size > 200 patients
Sensitivity 0.94 [0.91, 0.97]
GRADE not reported
5 studies · 1920 participants
Patients suspected or confirmed with temporomandibular disorders (TMD)Fonseca Anamnestic Index (FAI) screening questionnaire (index test)Reference standard diagnosis (DC/TMD or RDC/TMD with imaging)Negative likelihood ratio (as reported in text and abstract)
Not specified
Negative likelihood ratio 0.14 [0.07, 0.27]
GRADE not reported
9 studies · 2381 participants
Patients suspected or confirmed with temporomandibular disorders (TMD)Fonseca Anamnestic Index (FAI) screening questionnaire (index test)Reference standard diagnosis (DC/TMD or RDC/TMD with imaging)Post-test probability after negative FAI at 20% pre-test probability
Not specified
Post-test probability (%) 3
GRADE not reported
9 studies · 2381 participants
Patients suspected or confirmed with temporomandibular disorders (TMD)Fonseca Anamnestic Index (FAI) screening questionnaire (index test)Reference standard diagnosis (DC/TMD or RDC/TMD with imaging)Pooled specificity
Not specified
Specificity 0.76 [0.57, 0.88]
GRADE not reported
9 studies · 2381 participants
Patients suspected or confirmed with temporomandibular disorders (TMD)Fonseca Anamnestic Index (FAI) screening questionnaire (index test)Reference standard diagnosis (DC/TMD or RDC/TMD with imaging)Pooled specificity
Not specified · Sensitivity analysis: excluding de Santis et al. 2014
Specificity 0.75
GRADE not reported
8 studies · 2271 participants
Patients suspected or confirmed with temporomandibular disorders (TMD)Fonseca Anamnestic Index (FAI) screening questionnaire (index test)Reference standard diagnosis (DC/TMD or RDC/TMD with imaging)Pooled specificity
Not specified · Subgroup: Chinese population
Specificity 0.88 [0.63, 1.00]
GRADE not reported
1 study · 923 participants
Patients suspected or confirmed with temporomandibular disorders (TMD)Fonseca Anamnestic Index (FAI) screening questionnaire (index test)Reference standard diagnosis (DC/TMD or RDC/TMD with imaging)Positive likelihood ratio (as reported in text and abstract)
Not specified
Positive likelihood ratio 3.28 [2.46, 4.10]
GRADE not reported
9 studies · 2381 participants
Patients suspected or confirmed with temporomandibular disorders (TMD)Fonseca Anamnestic Index (FAI) screening questionnaire (index test)Reference standard diagnosis (DC/TMD or RDC/TMD with imaging)Post-test probability after positive FAI at 20% pre-test probability
Not specified
Post-test probability (%) 48
GRADE not reported
9 studies · 2381 participants
Patients suspected or confirmed with temporomandibular disorders (TMD)Fonseca Anamnestic Index (FAI) screening questionnaire (index test)Reference standard diagnosis (DC/TMD or RDC/TMD with imaging)Pooled sensitivity
Not specified · Subgroup: Male proportion of 50%
Sensitivity 0.75 [0.55, 0.96]
GRADE not reported
Studies not reported
Patients suspected or confirmed with temporomandibular disorders (TMD)Fonseca Anamnestic Index (FAI) screening questionnaire (index test)Reference standard diagnosis (DC/TMD or RDC/TMD with imaging)Pooled sensitivity
Not specified · Sensitivity analysis: excluding de Santis et al. 2014
Sensitivity 0.92
GRADE not reported
8 studies · 2271 participants
Patients suspected or confirmed with temporomandibular disorders (TMD)Fonseca Anamnestic Index (FAI) screening questionnaire (index test)Reference standard diagnosis (DC/TMD or RDC/TMD with imaging)Pooled specificity
Not specified · Subgroup: Sample size > 200 patients
Specificity 0.71 [0.49, 0.94]
GRADE not reported
5 studies · 1920 participants
Patients suspected or confirmed with temporomandibular disorders (TMD)Fonseca Anamnestic Index (FAI) screening questionnaire (index test)Reference standard diagnosis (DC/TMD or RDC/TMD with imaging)Pooled specificity
Not specified · Subgroup: Male proportion of 50%
Specificity 0.67 [0.27, 1.00]
GRADE not reported
Studies not reported
Patients suspected or confirmed with temporomandibular disorders (TMD)Fonseca Anamnestic Index (FAI) screening questionnaire (index test)Reference standard diagnosis (DC/TMD or RDC/TMD with imaging)Pooled sensitivity
Not specified
Sensitivity 0.89 [0.82, 0.94]
GRADE not reported
9 studies · 2381 participants
Patients suspected or confirmed with temporomandibular disorders (TMD)Fonseca Anamnestic Index (FAI) screening questionnaire (index test)Reference standard diagnosis (DC/TMD or RDC/TMD with imaging)Pooled specificity
Not specified · Subgroup: Non-Chinese populations
Specificity 0.74 [0.57, 0.90]
GRADE not reported
8 studies · 1458 participants
Patients suspected or confirmed with temporomandibular disorders (TMD)Fonseca Anamnestic Index (FAI) screening questionnaire (index test)Reference standard diagnosis (DC/TMD or RDC/TMD with imaging)Summary area under the SROC curve
Not specified
AUC 0.91 [0.88, 0.93]
GRADE not reported
9 studies · 2381 participants
Patients suspected of or diagnosed with temporomandibular disorders (TMD)Fonseca Anamnestic Index (FAI or short-form SFAI) questionnaireReference standard (DC/TMD or RDC/TMD with clinical, imaging or arthroscopic examination)Positive likelihood ratio of FAI for TMD
Value plotted in Fig. 6 forest plot
Positive likelihood ratio 3.68 [1.99, 6.83]
GRADE not reported
9 studies · 2381 participants
Patients suspected of or diagnosed with temporomandibular disorders (TMD)Fonseca Anamnestic Index (FAI or short-form SFAI) questionnaireReference standard (DC/TMD or RDC/TMD with clinical, imaging or arthroscopic examination)Diagnostic score of FAI for TMDDiagnostic score (log DOR) 3.28 [2.46, 4.10]
GRADE not reported
9 studies · 2381 participants

Included primary studies 9

Open in Studies
StudyYearAlso included byOutcomes it informs hereTrial data
Berni 2015
Accuracy of the Fonseca anamnestic index in the identification of myogenous temporomandibular disorder in female community cases.
PMID:26118509
2015this review onlynot statednot extracted yet
de Santis 2014
Accuracy study of the main screening tools for temporomandibular disorder in children and adolescents.
PMID:24411155
2014this review onlynot statednot extracted yet
Kaynak 2023
The accuracy and reliability of the Turkish version of the Fonseca anamnestic index in temporomandibular disorders.
PMID:32840464
2023this review onlynot statednot extracted yet
Kothari 2025
Temporomandibular Disorders in Brain Injury Patients and Diagnostic Accuracy of the Assessment Tools.
PMID:39928040
2025this review onlynot statednot extracted yet
Pires 2018
Analysis of the accuracy and reliability of the Short-Form Fonseca Anamnestic Index in the diagnosis of myogenous temporomandibular…
PMID:29519746
2018this review onlynot statednot extracted yet
Stasiak 2023
TMD diagnosis: Sensitivity and specificity of the Fonseca Anamnestic Index.
PMID:33108257
2023this review onlynot statednot extracted yet
Yap 2024
Accuracy of the Fonseca Anamnestic Index for identifying pain-related and/or intra-articular Temporomandibular Disorders.
PMID:34259594
2024this review onlynot statednot extracted yet
Yarasca-Berrocal 2022
Predictability and Accuracy of the Short-Form Fonseca Anamnestic Index in Relation to the Modified Helkimo Index for the Diagnosis of…
PMID:35462743
2022this review onlynot statednot extracted yet
Zagalaz-Anula 2021
The Short Form of the Fonseca Anamnestic Index for the Screening of Temporomandibular Disorders: Validity and Reliability in a…
PMID:34945153
2021this review onlynot statednot extracted yet

Review question

ElementPlanned (methods)Found (results)
PopulationPatients suspected or confirmed with TMD with explicit diagnostic criteriaPatients with suspected or confirmed TMD (n=2381); children to older adults
InterventionFonseca Anamnestic Index (FAI) as screening or diagnostic assessmentFAI (n=7 studies) and short-form SFAI (n=2 studies)
ComparisonReference standard (clinical symptoms with imaging or arthroscopic examination)DC/TMD (n=5 studies) or RDC/TMD (n=4 studies) reference standard
OutcomesSensitivity, specificity, true/false positives and negatives, DOR, AUCPooled sensitivity, specificity, PLR, NLR, DOR, summary AUC
Study designsProspective and retrospective diagnostic studies, English languageDiagnostic accuracy studies (n=9), mostly cross-sectional
TimingNot specifiedNot specified