Non-Cochrane · other · PM41844928
Age estimation using the pulp-to-tooth volume ratio of canines based on cone-beam computed tomography: a systematic review and meta-analysis.
da Silva Mirela Cristina, Panciera Maria Clara, Pinto Paulo Henrique Viana, et al. · Scientific reports · 2026 · PubMed · doi:10.1038/s41598-026-44605-2
Findings
Population Individuals aged 10 to 82 years with fully developed canines (canines analyzed by CBCT)
2 findings
| Pulp-to-tooth volume ratio of canines measured on CBCT (index measure) | Chronological age (reference) | Pearson correlation between pulp-to-tooth volume ratio and chronological age Not applicable · Forensic age estimation; CBCT of canines · Sensitivity analysis: outlier studies removed (Prakash, Souza et al., Star et al.) | Pearson correlation coefficient (r) -0.70 [-0.76, -0.62] GRADE not reported 6 studies · 939 participants |
| Pulp-to-tooth volume ratio of canines measured on CBCT (index measure) | Chronological age (reference) | Pearson correlation between pulp-to-tooth volume ratio and chronological age Not applicable · Forensic age estimation; CBCT of canines · All studies (outliers included) | Pearson correlation coefficient (r) -0.59 [-0.72, -0.41] GRADE not reported 9 studies · 4755 participants |
Included primary studies 10
Open in Studies| Study | Year | Also included by | Outcomes it informs here | Trial data |
|---|---|---|---|---|
| Abdinian 2021 Age Estimation Based on Pulp–Tooth Volume Ratio of Anterior Teeth in Cone-Beam Computed Tomographic Images in a Selected Population: A… DOI:10.3390/app11219984 | 2021 | this review only | Pearson correlation between pulp-to-tooth volume ratio and chronological age | not extracted yet |
| Anjani 2023 Dental age estimation in Indonesian adults: An investigation of the maxillary canine pulp-to-tooth volume ratio using cone-beam computed… PMID:37799738 | 2023 | this review only | Pearson correlation between pulp-to-tooth volume ratio and chronological age | not extracted yet |
| Asif 2019 Dental age estimation in Malaysian adults based on volumetric analysis of pulp/tooth ratio using CBCT data. PMID:30415192 | 2019 | this review only | Pearson correlation between pulp-to-tooth volume ratio and chronological age | not extracted yet |
| Jadhav 2023 Estimation of age implementing pulp tooth volume ratio in maxillary canines of an Indian population by means of CBCT scans. PMID:37955095 | 2024 | this review only | not stated | not extracted yet |
| Jagannathan 2011 Age estimation in an Indian population using pulp/tooth volume ratio of mandibular canines obtained from cone beam computed tomography. PMID:21841263 | 2011 | this review only | Pearson correlation between pulp-to-tooth volume ratio and chronological age | not extracted yet |
| Prakash 2024 Age estimation in Indian soldiers: Maxillary anterior tooth pulp/tooth volume ratio analysis with cone beam computed tomography. PMID:39071747 | 2024 | this review only | Pearson correlation between pulp-to-tooth volume ratio and chronological age | not extracted yet |
| Rathore 2022 Mandibular Teeth as Predictors in Forensic Age Estimation: A Cone-Beam Computed Tomography-Based Pulp Volume Regression Study. PMID:37249999 | 2023 | this review only | Pearson correlation between pulp-to-tooth volume ratio and chronological age | not extracted yet |
| Souza 2024 Age estimation by volumetric analysis of teeth using cone beam computed tomography. PMID:38589600 | 2024 | this review only | Pearson correlation between pulp-to-tooth volume ratio and chronological age | not extracted yet |
| Star 2010 Human dental age estimation by calculation of pulp-tooth volume ratios yielded on clinically acquired cone beam computed tomography images… PMID:21182523 | 2011 | this review only | Pearson correlation between pulp-to-tooth volume ratio and chronological age | not extracted yet |
| Zhan 2020 Age estimation in Western Chinese adults by pulp–tooth volume ratios using cone-beam computed tomography DOI:10.1080/00450618.2020.1729415 | 2020 | this review only | Pearson correlation between pulp-to-tooth volume ratio and chronological age | not extracted yet |
Review question
| Element | Planned (methods) | Found (results) |
|---|---|---|
| Population | Individuals with fully developed canines or adults | Samples from Belgium, Brazil, China, India, Indonesia, Iran and Malaysia, ages 10 to 82 years (4,793 canines analyzed per the text; 4,755 in the pooled forest plot) |
| Intervention | Pulp-to-tooth volume ratio measured on CBCT | CBCT pulp-to-tooth volume ratio of maxillary and mandibular canines (n=10 studies; 9 in meta-analysis) |
| Comparison | Chronological age | Chronological age |
| Outcomes | Correlation between pulp-to-tooth volume ratio and chronological age (reliability for age estimation) | Pearson correlation coefficient (15 coefficients from 9 studies); one study related estimated age to chronological age and was not pooled |
| Study designs | Studies of canines measured by CBCT with canine results reported separately; excluded artificial intelligence only studies, animal studies, book chapters, reviews, case reports and conference proceedings | 10 observational studies, all rated low risk of bias on the JBI checklist |
| Timing | Not specified | Not specified |