Non-Cochrane · intervention · PM41756535

Effect of Flapless Laser Corticotomy on Maxillary Canine Retraction: a Systematic Review and Meta-Analysis.

Jančauskaitė Ernesta, Varoneckaitė Mariam, Baliutavičiūtė Agnė, et al. · Journal of oral & maxillofacial research · 2025 · PubMed · doi:10.5037/jomr.2025.16402

Findings

Population Patients undergoing fixed orthodontic treatment with maxillary first premolar extraction and canine distalization

6 findings

Flapless laser corticotomy (Er:YAG or Er,Cr:YSGG laser)Conventional orthodontic canine retraction without corticotomy (split-mouth control side)Canine retraction distance (mm)
4 months · Orthodontic treatment, fixed appliances, extraction-based
MD -0.04 [-0.13, 0.05]
GRADE not reported
2 studies · 29 participants
Flapless laser corticotomy (Er:YAG or Er,Cr:YSGG laser)Conventional orthodontic canine retraction without corticotomy (split-mouth control side)Canine retraction distance (mm)
1 month · Orthodontic treatment, fixed appliances, extraction-based
MD 0.83 [0.30, 1.35]
GRADE not reported
4 studies · 55 participants
Flapless laser corticotomy (Er:YAG or Er,Cr:YSGG laser)Conventional orthodontic canine retraction without corticotomy (split-mouth control side)Molar anchorage loss (mm)
1 month · Orthodontic treatment, fixed appliances, extraction-based
MD -0.10 [-0.19, -0.01]
GRADE not reported
3 studies · 43 participants
Flapless laser corticotomy (Er:YAG or Er,Cr:YSGG laser)Conventional orthodontic canine retraction without corticotomy (split-mouth control side)Canine retraction distance (mm)
3 months · Orthodontic treatment, fixed appliances, extraction-based
MD 0.03 [-0.18, 0.24]
GRADE not reported
3 studies · 43 participants
Flapless laser corticotomy (Er:YAG or Er,Cr:YSGG laser)Conventional orthodontic canine retraction without corticotomy (split-mouth control side)Canine rotation (degrees)
1 month · Orthodontic treatment, fixed appliances, extraction-based
MD 1.20 [-1.03, 3.42]
GRADE not reported
3 studies · 43 participants
Flapless laser corticotomy (Er:YAG or Er,Cr:YSGG laser)Conventional orthodontic canine retraction without corticotomy (split-mouth control side)Canine retraction distance (mm)
2 months · Orthodontic treatment, fixed appliances, extraction-based
MD 0.44 [0.09, 0.79]
GRADE not reported
3 studies · 43 participants

Included primary studies 7

Open in Studies
StudyYearAlso included byOutcomes it informs hereTrial data
Alfawal 2018
Evaluation of piezocision and laser-assisted flapless corticotomy in the acceleration of canine retraction: a randomized controlled trial.
PMID:29454369
20181 other reviewCanine retraction distance (mm); Canine rotation (degrees); Molar anchorage loss (mm)not extracted yet
Bakr 2023
Effects of Flapless Laser Corticotomy in Upper and Lower Canine Retraction: A Split-mouth, Randomized Controlled Trial.
PMID:37159786
20231 other reviewCanine retraction distance (mm); Canine rotation (degrees); Molar anchorage loss (mm)not extracted yet
Jaber 2022
Evaluation of the efficacy of laser-assisted flapless corticotomy in accelerating canine retraction: a split-mouth randomized controlled…
PMID:33876339
20221 other reviewnot statednot extracted yet
Mahmoudzadeh 2020
Efficacy of Er,Cr Laser incision Corticotomy in Rapid Maxillary Canine Retraction: A Split-Mouth Randomized Clinical Trial.
PMID:33425295
20201 other reviewCanine retraction distance (mm); Canine rotation (degrees); Molar anchorage loss (mm)not extracted yet
Chauhan 2022
laser assisted accelerated orthodontics – a split mouth study
DOI:10.1080/27705781.2022.2073677
2022this review onlynot statednot extracted yet
Salman 2014
matched by author and year (probable)
NRthis review onlynot statednot extracted yet
Toodehzaeim 2024
Effect of laser corticotomy on canine retraction rate: a split-mouth randomized clinical trial.
PMID:38609926
2024this review onlyCanine retraction distance (mm)not extracted yet

Overlap with other reviews

Reviews that include the same primary studies are not independent evidence. Shared counts match studies by PMID, DOI or NCT, and otherwise by author and year (a probable match). Only the non-Cochrane dental reviews have study lists, so overlap with Cochrane reviews is not counted yet.

Review question

ElementPlanned (methods)Found (results)
PopulationPatients with fixed orthodontic appliances after maxillary first premolar extraction and canine distalization, any ageOrthodontic patients with first premolar extraction (103 patients in 7 studies; 55 in meta-analysis); age 15 to 30 years
InterventionLaser-assisted flapless corticotomyEr:YAG or Er,Cr:YSGG laser corticotomy (n=7)
ComparisonConventional orthodontic treatment without corticotomyCanine retraction without intervention on contralateral side (n=7)
OutcomesCanine distalization distance (mm); canine rotation; molar anchorage lossCanine retraction rate; canine rotation; molar anchorage loss; pain, pulp vitality, root resorption (narrative)
Study designsSplit-mouth randomized clinical trialsSplit-mouth RCTs (n=7)
TimingNot specified1 to 4 months

AMSTAR 2 items

Two independent extractors rated each item. Their ratings are shown side by side because they have not been reconciled yet. The overall rating follows Shea et al. 2017: one critical flaw gives Low, more than one gives Critically Low.

ItemExtractor AExtractor BAgree
1Research question includes PICO componentsYesYesyes
2Protocol established before the reviewcriticalPartial YesPartial Yesyes
3Choice of study designs explainedYesYesyes
4Comprehensive literature searchcriticalNoPartial Yesno
5Study selection in duplicateYesYesyes
6Data extraction in duplicateYesYesyes
7List of excluded studies with reasonscriticalYesYesyes
8Included studies described in detailYesYesyes
9Risk of bias assessed satisfactorilycriticalRCT: Yes · NRSI: N/ANRSI: N/A · RCT: Yesno
10Funding of included studies reportedNoNoyes
11Appropriate meta-analysis methodscriticalRCT: No · NRSI: N/ANRSI: N/A · RCT: Partial Yesno
12Impact of risk of bias on the pooled resultsNoNoyes
13Risk of bias accounted for in interpretationcriticalYesYesyes
14Heterogeneity explainedNoNoyes
15Publication bias investigatedcriticalNoNoyes
16Conflicts of interest reportedYesYesyes
OverallCritically LowLowno