Non-Cochrane · NMA · PM41714848

Accuracy of Static, Dynamic, and Robotic Guided Surgery in Immediate Implant Placement: A Systematic Review and Network Meta-Analysis.

Nava Paolo, Sabri Hamoun, Hazrati Parham, et al. · Clinical oral implants research · 2026 · PubMed · doi:10.1111/clr.70100

Findings

172 findings

Population
Adults with at least one non-restorable or failing tooth undergoing immediate implant placement (within 24 h of extraction)fully-guided static CAIS (FG-sCAIS)freehand (FH) placementLinear deviation at the implant platform
Immediate placement; CBCT after surgery · Clinical studies of immediate implant placement; accuracy assessed by CBCT superimposition · Post hoc sensitivity NMA: RCTs plus low- and moderate-risk non-randomized studies (contrast-based frequentist, Tables S7, S10, S13)
MD -0.552 [-0.597, -0.507]
GRADE not reported
Studies not reported
Adults with at least one non-restorable or failing tooth undergoing immediate implant placement (within 24 h of extraction)fully-guided static CAIS (FG-sCAIS)freehand (FH) placementAngular deviation between planned and actual implant position
Immediate placement; CBCT after surgery · Clinical studies of immediate implant placement; accuracy assessed by CBCT superimposition · Post hoc sensitivity NMA: RCT-only (contrast-based frequentist, Tables S16, S19, S22)
MD -4.35 [-6.63, -2.07]
GRADE not reported
Studies not reported
Adults with at least one non-restorable or failing tooth undergoing immediate implant placement (within 24 h of extraction)fully-guided static CAIS (FG-sCAIS)freehand (FH) placementLinear deviation at the implant platform
Immediate placement; CBCT after surgery · Clinical studies of immediate implant placement; accuracy assessed by CBCT superimposition · Primary mixed-effects NMA, pairwise contrast with FDR-adjusted p (Table S2)
MD -0.546 [-0.623, -0.468]
Low
Downgraded: risk of bias, publication bias
2 studies
Adults with at least one non-restorable or failing tooth undergoing immediate implant placement (within 24 h of extraction)fully-guided static CAIS (FG-sCAIS)freehand (FH) placementLinear deviation at the implant platform
Immediate placement; CBCT after surgery · Clinical studies of immediate implant placement; accuracy assessed by CBCT superimposition · Mixed-effects NMA model coefficient vs freehand (Table 5)
MD -0.543
Low
Downgraded: risk of bias, publication bias
2 studies
Adults with at least one non-restorable or failing tooth undergoing immediate implant placement (within 24 h of extraction)fully-guided static CAIS (FG-sCAIS)freehand (FH) placementLinear deviation at the implant platform
Immediate placement; CBCT after surgery · Clinical studies of immediate implant placement; accuracy assessed by CBCT superimposition · Post hoc sensitivity NMA: RCT-only (contrast-based frequentist, Tables S16, S19, S22)
MD -0.77 [-1.14, -0.4]
GRADE not reported
Studies not reported
Adults with at least one non-restorable or failing tooth undergoing immediate implant placement (within 24 h of extraction)fully-guided static CAIS (FG-sCAIS)freehand (FH) placementLinear deviation at the implant apex
Immediate placement; CBCT after surgery · Clinical studies of immediate implant placement; accuracy assessed by CBCT superimposition · Primary mixed-effects NMA, pairwise contrast with FDR-adjusted p (Table S2)
MD -0.823 [-1.533, -0.113]
Low
Downgraded: risk of bias, publication bias
2 studies
Adults with at least one non-restorable or failing tooth undergoing immediate implant placement (within 24 h of extraction)fully-guided static CAIS (FG-sCAIS)freehand (FH) placementAngular deviation between planned and actual implant position
Immediate placement; CBCT after surgery · Clinical studies of immediate implant placement; accuracy assessed by CBCT superimposition · Mixed-effects NMA model coefficient vs freehand (Table 5)
MD -1.854
Low
Downgraded: risk of bias, publication bias
2 studies
Adults with at least one non-restorable or failing tooth undergoing immediate implant placement (within 24 h of extraction)fully-guided static CAIS (FG-sCAIS)freehand (FH) placementLinear deviation at the implant apex
Immediate placement; CBCT after surgery · Clinical studies of immediate implant placement; accuracy assessed by CBCT superimposition · Post hoc sensitivity NMA: RCT-only (contrast-based frequentist, Tables S16, S19, S22)
MD -0.533 [-0.958, -0.109]
GRADE not reported
Studies not reported
Adults with at least one non-restorable or failing tooth undergoing immediate implant placement (within 24 h of extraction)fully-guided static CAIS (FG-sCAIS)freehand (FH) placementAngular deviation between planned and actual implant position
Immediate placement; CBCT after surgery · Clinical studies of immediate implant placement; accuracy assessed by CBCT superimposition · Post hoc sensitivity NMA: RCTs plus low- and moderate-risk non-randomized studies (contrast-based frequentist, Tables S7, S10, S13)
MD -3.46 [-5.37, -1.55]
GRADE not reported
Studies not reported
Adults with at least one non-restorable or failing tooth undergoing immediate implant placement (within 24 h of extraction)fully-guided static CAIS (FG-sCAIS)freehand (FH) placementAngular deviation between planned and actual implant position
Immediate placement; CBCT after surgery · Clinical studies of immediate implant placement; accuracy assessed by CBCT superimposition · Primary mixed-effects NMA, pairwise contrast with FDR-adjusted p (Table S2)
MD -1.83 [-2.58, -1.09]
Low
Downgraded: risk of bias, publication bias
2 studies
Adults with at least one non-restorable or failing tooth undergoing immediate implant placement (within 24 h of extraction)fully-guided static CAIS (FG-sCAIS)freehand (FH) placementLinear deviation at the implant apex
Immediate placement; CBCT after surgery · Clinical studies of immediate implant placement; accuracy assessed by CBCT superimposition · Post hoc sensitivity NMA: RCTs plus low- and moderate-risk non-randomized studies (contrast-based frequentist, Tables S7, S10, S13)
MD -0.859 [-1.27, -0.448]
GRADE not reported
Studies not reported
Adults with at least one non-restorable or failing tooth undergoing immediate implant placement (within 24 h of extraction)half-guided static CAIS (HG-sCAIS)freehand (FH) placementAngular deviation between planned and actual implant position
Immediate placement; CBCT after surgery · Clinical studies of immediate implant placement; accuracy assessed by CBCT superimposition · Mixed-effects NMA model coefficient vs freehand (Table 5)
MD -1.729
Low
Downgraded: publication bias
1 study
Adults with at least one non-restorable or failing tooth undergoing immediate implant placement (within 24 h of extraction)half-guided static CAIS (HG-sCAIS)freehand (FH) placementLinear deviation at the implant platform
Immediate placement; CBCT after surgery · Clinical studies of immediate implant placement; accuracy assessed by CBCT superimposition · Mixed-effects NMA model coefficient vs freehand (Table 5)
MD -0.274
Low
Downgraded: publication bias
1 study
Adults with at least one non-restorable or failing tooth undergoing immediate implant placement (within 24 h of extraction)half-guided static CAIS (HG-sCAIS)freehand (FH) placementLinear deviation at the implant apex
Immediate placement; CBCT after surgery · Clinical studies of immediate implant placement; accuracy assessed by CBCT superimposition · Primary mixed-effects NMA, pairwise contrast with FDR-adjusted p (Table S2)
MD -0.551 [-1.569, 0.466]
Low
Downgraded: publication bias
1 study
Adults with at least one non-restorable or failing tooth undergoing immediate implant placement (within 24 h of extraction)half-guided static CAIS (HG-sCAIS)freehand (FH) placementLinear deviation at the implant apex
Immediate placement; CBCT after surgery · Clinical studies of immediate implant placement; accuracy assessed by CBCT superimposition · Mixed-effects NMA model coefficient vs freehand (Table 5)
MD -1.229
Low
Downgraded: publication bias
1 study
Adults with at least one non-restorable or failing tooth undergoing immediate implant placement (within 24 h of extraction)half-guided static CAIS (HG-sCAIS)freehand (FH) placementAngular deviation between planned and actual implant position
Immediate placement; CBCT after surgery · Clinical studies of immediate implant placement; accuracy assessed by CBCT superimposition · Post hoc sensitivity NMA: RCTs plus low- and moderate-risk non-randomized studies (contrast-based frequentist, Tables S7, S10, S13)
MD -3.52 [-6.84, -0.2]
GRADE not reported
Studies not reported
Adults with at least one non-restorable or failing tooth undergoing immediate implant placement (within 24 h of extraction)half-guided static CAIS (HG-sCAIS)freehand (FH) placementLinear deviation at the implant platform
Immediate placement; CBCT after surgery · Clinical studies of immediate implant placement; accuracy assessed by CBCT superimposition · Post hoc sensitivity NMA: RCT-only (contrast-based frequentist, Tables S16, S19, S22)
MD -0.69 [-1.43, 0.06]
GRADE not reported
Studies not reported
Adults with at least one non-restorable or failing tooth undergoing immediate implant placement (within 24 h of extraction)half-guided static CAIS (HG-sCAIS)freehand (FH) placementLinear deviation at the implant apex
Immediate placement; CBCT after surgery · Clinical studies of immediate implant placement; accuracy assessed by CBCT superimposition · Post hoc sensitivity NMA: RCT-only (contrast-based frequentist, Tables S16, S19, S22)
MD -1.063 [-2.255, 0.128]
GRADE not reported
Studies not reported
Adults with at least one non-restorable or failing tooth undergoing immediate implant placement (within 24 h of extraction)half-guided static CAIS (HG-sCAIS)freehand (FH) placementLinear deviation at the implant platform
Immediate placement; CBCT after surgery · Clinical studies of immediate implant placement; accuracy assessed by CBCT superimposition · Primary mixed-effects NMA, pairwise contrast with FDR-adjusted p (Table S2)
MD -0.282 [-0.554, -0.011]
Low
Downgraded: publication bias
1 study
Adults with at least one non-restorable or failing tooth undergoing immediate implant placement (within 24 h of extraction)half-guided static CAIS (HG-sCAIS)freehand (FH) placementLinear deviation at the implant platform
Immediate placement; CBCT after surgery · Clinical studies of immediate implant placement; accuracy assessed by CBCT superimposition · Post hoc sensitivity NMA: RCTs plus low- and moderate-risk non-randomized studies (contrast-based frequentist, Tables S7, S10, S13)
MD -0.249 [-0.423, -0.075]
GRADE not reported
Studies not reported
Adults with at least one non-restorable or failing tooth undergoing immediate implant placement (within 24 h of extraction)half-guided static CAIS (HG-sCAIS)freehand (FH) placementLinear deviation at the implant apex
Immediate placement; CBCT after surgery · Clinical studies of immediate implant placement; accuracy assessed by CBCT superimposition · Post hoc sensitivity NMA: RCTs plus low- and moderate-risk non-randomized studies (contrast-based frequentist, Tables S7, S10, S13)
MD -0.569 [-1.025, -0.113]
GRADE not reported
Studies not reported
Adults with at least one non-restorable or failing tooth undergoing immediate implant placement (within 24 h of extraction)half-guided static CAIS (HG-sCAIS)freehand (FH) placementAngular deviation between planned and actual implant position
Immediate placement; CBCT after surgery · Clinical studies of immediate implant placement; accuracy assessed by CBCT superimposition · Post hoc sensitivity NMA: RCT-only (contrast-based frequentist, Tables S16, S19, S22)
MD -6.11 [-10.76, -1.45]
GRADE not reported
Studies not reported
Adults with at least one non-restorable or failing tooth undergoing immediate implant placement (within 24 h of extraction)half-guided static CAIS (HG-sCAIS)freehand (FH) placementAngular deviation between planned and actual implant position
Immediate placement; CBCT after surgery · Clinical studies of immediate implant placement; accuracy assessed by CBCT superimposition · Primary mixed-effects NMA, pairwise contrast with FDR-adjusted p (Table S2)
MD -2.13 [-3.62, -0.64]
Low
Downgraded: publication bias
1 study
Adults with at least one non-restorable or failing tooth undergoing immediate implant placement (within 24 h of extraction)dynamic CAIS (dCAIS)freehand (FH) placementLinear deviation at the implant apex
Immediate placement; CBCT after surgery · Clinical studies of immediate implant placement; accuracy assessed by CBCT superimposition · Post hoc sensitivity NMA: RCT-only (contrast-based frequentist, Tables S16, S19, S22)
MD -0.853 [-0.988, -0.719]
GRADE not reported
Studies not reported
Adults with at least one non-restorable or failing tooth undergoing immediate implant placement (within 24 h of extraction)dynamic CAIS (dCAIS)freehand (FH) placementLinear deviation at the implant platform
Immediate placement; CBCT after surgery · Clinical studies of immediate implant placement; accuracy assessed by CBCT superimposition · Post hoc sensitivity NMA: RCTs plus low- and moderate-risk non-randomized studies (contrast-based frequentist, Tables S7, S10, S13)
MD -0.728 [-0.77, -0.685]
GRADE not reported
Studies not reported
Adults with at least one non-restorable or failing tooth undergoing immediate implant placement (within 24 h of extraction)dynamic CAIS (dCAIS)freehand (FH) placementAngular deviation between planned and actual implant position
Immediate placement; CBCT after surgery · Clinical studies of immediate implant placement; accuracy assessed by CBCT superimposition · Primary mixed-effects NMA, pairwise contrast with FDR-adjusted p (Table S2)
MD -2.62 [-3.33, -1.91]
Low
Downgraded: risk of bias, publication bias
3 studies
Adults with at least one non-restorable or failing tooth undergoing immediate implant placement (within 24 h of extraction)dynamic CAIS (dCAIS)freehand (FH) placementLinear deviation at the implant platform
Immediate placement; CBCT after surgery · Clinical studies of immediate implant placement; accuracy assessed by CBCT superimposition · Post hoc sensitivity NMA: RCT-only (contrast-based frequentist, Tables S16, S19, S22)
MD -0.7 [-0.74, -0.66]
GRADE not reported
Studies not reported
Adults with at least one non-restorable or failing tooth undergoing immediate implant placement (within 24 h of extraction)dynamic CAIS (dCAIS)freehand (FH) placementLinear deviation at the implant apex
Immediate placement; CBCT after surgery · Clinical studies of immediate implant placement; accuracy assessed by CBCT superimposition · Mixed-effects NMA model coefficient vs freehand (Table 5)
MD -1.316
Low
Downgraded: risk of bias, publication bias
3 studies
Adults with at least one non-restorable or failing tooth undergoing immediate implant placement (within 24 h of extraction)dynamic CAIS (dCAIS)freehand (FH) placementAngular deviation between planned and actual implant position
Immediate placement; CBCT after surgery · Clinical studies of immediate implant placement; accuracy assessed by CBCT superimposition · Post hoc sensitivity NMA: RCT-only (contrast-based frequentist, Tables S16, S19, S22)
MD -3.23 [-5.23, -1.24]
GRADE not reported
Studies not reported
Adults with at least one non-restorable or failing tooth undergoing immediate implant placement (within 24 h of extraction)dynamic CAIS (dCAIS)freehand (FH) placementAngular deviation between planned and actual implant position
Immediate placement; CBCT after surgery · Clinical studies of immediate implant placement; accuracy assessed by CBCT superimposition · Mixed-effects NMA model coefficient vs freehand (Table 5)
MD -2.66
Low
Downgraded: risk of bias, publication bias
3 studies
Adults with at least one non-restorable or failing tooth undergoing immediate implant placement (within 24 h of extraction)dynamic CAIS (dCAIS)freehand (FH) placementLinear deviation at the implant platform
Immediate placement; CBCT after surgery · Clinical studies of immediate implant placement; accuracy assessed by CBCT superimposition · Mixed-effects NMA model coefficient vs freehand (Table 5)
MD -0.713
Low
Downgraded: risk of bias, publication bias
3 studies
Adults undergoing immediate implant placement (within 24 h of extraction)Fully guided static CAIS (FG-sCAIS)Freehand placement (FH)Apex linear deviation between planned and actual implant position
Immediately after planning/surgery; accuracy by superimposition of post-operative CBCT (or intraoral scan) on the plan · Clinical studies of immediate implant placement · Primary mixed-effects NMA: model coefficient vs FH reference (Table 5)
MD -0.81
Low
Downgraded: risk of bias, publication bias
2 studies
Adults with at least one non-restorable or failing tooth undergoing immediate implant placement (within 24 h of extraction)dynamic CAIS (dCAIS)freehand (FH) placementLinear deviation at the implant apex
Immediate placement; CBCT after surgery · Clinical studies of immediate implant placement; accuracy assessed by CBCT superimposition · Primary mixed-effects NMA, pairwise contrast with FDR-adjusted p (Table S2)
MD -1.37 [-1.845, -0.895]
Low
Downgraded: risk of bias, publication bias
3 studies
Adults with at least one non-restorable or failing tooth undergoing immediate implant placement (within 24 h of extraction)dynamic CAIS (dCAIS)freehand (FH) placementLinear deviation at the implant platform
Immediate placement; CBCT after surgery · Clinical studies of immediate implant placement; accuracy assessed by CBCT superimposition · Primary mixed-effects NMA, pairwise contrast with FDR-adjusted p (Table S2)
MD -0.711 [-0.769, -0.652]
Low
Downgraded: risk of bias, publication bias
3 studies
Adults with at least one non-restorable or failing tooth undergoing immediate implant placement (within 24 h of extraction)dynamic CAIS (dCAIS)freehand (FH) placementLinear deviation at the implant apex
Immediate placement; CBCT after surgery · Clinical studies of immediate implant placement; accuracy assessed by CBCT superimposition · Post hoc sensitivity NMA: RCTs plus low- and moderate-risk non-randomized studies (contrast-based frequentist, Tables S7, S10, S13)
MD -1.427 [-1.827, -1.027]
GRADE not reported
Studies not reported
Adults with at least one non-restorable or failing tooth undergoing immediate implant placement (within 24 h of extraction)dynamic CAIS (dCAIS)freehand (FH) placementAngular deviation between planned and actual implant position
Immediate placement; CBCT after surgery · Clinical studies of immediate implant placement; accuracy assessed by CBCT superimposition · Post hoc sensitivity NMA: RCTs plus low- and moderate-risk non-randomized studies (contrast-based frequentist, Tables S7, S10, S13)
MD -3.43 [-5.66, -1.2]
GRADE not reported
Studies not reported
Adults with at least one non-restorable or failing tooth undergoing immediate implant placement (within 24 h of extraction)robotic CAIS (rCAIS)freehand (FH) placementLinear deviation at the implant apex
Immediate placement; CBCT after surgery · Clinical studies of immediate implant placement; accuracy assessed by CBCT superimposition · Primary mixed-effects NMA, pairwise contrast with FDR-adjusted p (Table S2)
MD -1.25 [-2.102, -0.397]
Low
Downgraded: publication bias
1 study
Adults with at least one non-restorable or failing tooth undergoing immediate implant placement (within 24 h of extraction)robotic CAIS (rCAIS)freehand (FH) placementLinear deviation at the implant apex
Immediate placement; CBCT after surgery · Clinical studies of immediate implant placement; accuracy assessed by CBCT superimposition · Mixed-effects NMA model coefficient vs freehand (Table 5)
MD -1.428
Low
Downgraded: publication bias
1 study
Adults with at least one non-restorable or failing tooth undergoing immediate implant placement (within 24 h of extraction)robotic CAIS (rCAIS)freehand (FH) placementLinear deviation at the implant platform
Immediate placement; CBCT after surgery · Clinical studies of immediate implant placement; accuracy assessed by CBCT superimposition · Primary mixed-effects NMA, pairwise contrast with FDR-adjusted p (Table S2)
MD -0.694 [-0.947, -0.44]
Low
Downgraded: publication bias
1 study
Adults with at least one non-restorable or failing tooth undergoing immediate implant placement (within 24 h of extraction)robotic CAIS (rCAIS)freehand (FH) placementImplant placement accuracy (angular, platform and apex deviation)
Clinical studies of immediate implant placement; accuracy assessed by CBCT superimposition · RCT-only network
No RCT of robotic CAIS was available, so rCAIS was not included in the RCT-only network meta-analysis
No studies found
0 studies
Adults with at least one non-restorable or failing tooth undergoing immediate implant placement (within 24 h of extraction)robotic CAIS (rCAIS)freehand (FH) placementLinear deviation at the implant platform
Immediate placement; CBCT after surgery · Clinical studies of immediate implant placement; accuracy assessed by CBCT superimposition · Post hoc sensitivity NMA: RCTs plus low- and moderate-risk non-randomized studies (contrast-based frequentist, Tables S7, S10, S13)
MD -0.652 [-0.826, -0.479]
GRADE not reported
Studies not reported
Adults with at least one non-restorable or failing tooth undergoing immediate implant placement (within 24 h of extraction)robotic CAIS (rCAIS)freehand (FH) placementAngular deviation between planned and actual implant position
Immediate placement; CBCT after surgery · Clinical studies of immediate implant placement; accuracy assessed by CBCT superimposition · Post hoc sensitivity NMA: RCTs plus low- and moderate-risk non-randomized studies (contrast-based frequentist, Tables S7, S10, S13)
MD -5 [-8.06, -1.94]
GRADE not reported
Studies not reported
Adults with at least one non-restorable or failing tooth undergoing immediate implant placement (within 24 h of extraction)robotic CAIS (rCAIS)freehand (FH) placementLinear deviation at the implant platform
Immediate placement; CBCT after surgery · Clinical studies of immediate implant placement; accuracy assessed by CBCT superimposition · Mixed-effects NMA model coefficient vs freehand (Table 5)
MD -0.684
Low
Downgraded: publication bias
1 study
Adults with at least one non-restorable or failing tooth undergoing immediate implant placement (within 24 h of extraction)robotic CAIS (rCAIS)freehand (FH) placementAngular deviation between planned and actual implant position
Immediate placement; CBCT after surgery · Clinical studies of immediate implant placement; accuracy assessed by CBCT superimposition · Primary mixed-effects NMA, pairwise contrast with FDR-adjusted p (Table S2)
MD -3.67 [-4.89, -2.45]
Low
Downgraded: publication bias
1 study
Adults with at least one non-restorable or failing tooth undergoing immediate implant placement (within 24 h of extraction)robotic CAIS (rCAIS)freehand (FH) placementLinear deviation at the implant apex
Immediate placement; CBCT after surgery · Clinical studies of immediate implant placement; accuracy assessed by CBCT superimposition · Post hoc sensitivity NMA: RCTs plus low- and moderate-risk non-randomized studies (contrast-based frequentist, Tables S7, S10, S13)
MD -1.144 [-1.676, -0.613]
GRADE not reported
Studies not reported
Adults with at least one non-restorable or failing tooth undergoing immediate implant placement (within 24 h of extraction)robotic CAIS (rCAIS)freehand (FH) placementAngular deviation between planned and actual implant position
Immediate placement; CBCT after surgery · Clinical studies of immediate implant placement; accuracy assessed by CBCT superimposition · Mixed-effects NMA model coefficient vs freehand (Table 5)
MD -3.357
Low
Downgraded: publication bias
1 study
Adults with at least one non-restorable or failing tooth undergoing immediate implant placement (within 24 h of extraction)dynamic CAIS (dCAIS)fully-guided static CAIS (FG-sCAIS)Linear deviation at the implant apex
Immediate placement; CBCT after surgery · Clinical studies of immediate implant placement; accuracy assessed by CBCT superimposition · Primary mixed-effects NMA, pairwise contrast with FDR-adjusted p (Table S2)
MD -0.547 [-1.157, -0.063]
Low
Downgraded: publication bias
2 studies
Adults with at least one non-restorable or failing tooth undergoing immediate implant placement (within 24 h of extraction)dynamic CAIS (dCAIS)fully-guided static CAIS (FG-sCAIS)Linear deviation at the implant platform
Immediate placement; CBCT after surgery · Clinical studies of immediate implant placement; accuracy assessed by CBCT superimposition · Post hoc sensitivity NMA: RCTs plus low- and moderate-risk non-randomized studies (contrast-based frequentist, Tables S7, S10, S13)
MD -0.176 [-0.214, -0.138]
GRADE not reported
Studies not reported
Adults with at least one non-restorable or failing tooth undergoing immediate implant placement (within 24 h of extraction)dynamic CAIS (dCAIS)fully-guided static CAIS (FG-sCAIS)Linear deviation at the implant apex
Immediate placement; CBCT after surgery · Clinical studies of immediate implant placement; accuracy assessed by CBCT superimposition · Post hoc sensitivity NMA: RCTs plus low- and moderate-risk non-randomized studies (contrast-based frequentist, Tables S7, S10, S13)
MD -0.568 [-0.959, -0.178]
GRADE not reported
Studies not reported
Adults with at least one non-restorable or failing tooth undergoing immediate implant placement (within 24 h of extraction)dynamic CAIS (dCAIS)fully-guided static CAIS (FG-sCAIS)Linear deviation at the implant platform
Immediate placement; CBCT after surgery · Clinical studies of immediate implant placement; accuracy assessed by CBCT superimposition · Primary mixed-effects NMA, pairwise contrast with FDR-adjusted p (Table S2)
MD -0.165 [-0.234, -0.096]
Low
Downgraded: publication bias
2 studies
Adults with at least one non-restorable or failing tooth undergoing immediate implant placement (within 24 h of extraction)dynamic CAIS (dCAIS)fully-guided static CAIS (FG-sCAIS)Angular deviation between planned and actual implant position
Immediate placement; CBCT after surgery · Clinical studies of immediate implant placement; accuracy assessed by CBCT superimposition · Post hoc sensitivity NMA: RCTs plus low- and moderate-risk non-randomized studies (contrast-based frequentist, Tables S7, S10, S13)
MD 0.03 [-2.08, 2.14]
GRADE not reported
Studies not reported
Adults with at least one non-restorable or failing tooth undergoing immediate implant placement (within 24 h of extraction)dynamic CAIS (dCAIS)fully-guided static CAIS (FG-sCAIS)Linear deviation at the implant apex
Immediate placement; CBCT after surgery · Clinical studies of immediate implant placement; accuracy assessed by CBCT superimposition · Post hoc sensitivity NMA: RCT-only (contrast-based frequentist, Tables S16, S19, S22)
MD -0.32 [-0.723, 0.082]
GRADE not reported
Studies not reported
Adults with at least one non-restorable or failing tooth undergoing immediate implant placement (within 24 h of extraction)dynamic CAIS (dCAIS)fully-guided static CAIS (FG-sCAIS)Linear deviation at the implant platform
Immediate placement; CBCT after surgery · Clinical studies of immediate implant placement; accuracy assessed by CBCT superimposition · Post hoc sensitivity NMA: RCT-only (contrast-based frequentist, Tables S16, S19, S22)
MD 0.07 [-0.3, 0.44]
GRADE not reported
Studies not reported
Adults with at least one non-restorable or failing tooth undergoing immediate implant placement (within 24 h of extraction)dynamic CAIS (dCAIS)fully-guided static CAIS (FG-sCAIS)Angular deviation between planned and actual implant position
Immediate placement; CBCT after surgery · Clinical studies of immediate implant placement; accuracy assessed by CBCT superimposition · Primary mixed-effects NMA, pairwise contrast with FDR-adjusted p (Table S2)
MD -0.79 [-1.27, -0.31]
Low
Downgraded: publication bias
2 studies
Adults with at least one non-restorable or failing tooth undergoing immediate implant placement (within 24 h of extraction)dynamic CAIS (dCAIS)fully-guided static CAIS (FG-sCAIS)Angular deviation between planned and actual implant position
Immediate placement; CBCT after surgery · Clinical studies of immediate implant placement; accuracy assessed by CBCT superimposition · Post hoc sensitivity NMA: RCT-only (contrast-based frequentist, Tables S16, S19, S22)
MD 1.12 [-1.19, 3.42]
GRADE not reported
Studies not reported
Adults with at least one non-restorable or failing tooth undergoing immediate implant placement (within 24 h of extraction)dynamic CAIS (dCAIS)half-guided static CAIS (HG-sCAIS)Linear deviation at the implant apex
Immediate placement; CBCT after surgery · Clinical studies of immediate implant placement; accuracy assessed by CBCT superimposition · Post hoc sensitivity NMA: RCT-only (contrast-based frequentist, Tables S16, S19, S22)
MD 0.21 [-0.974, 1.394]
GRADE not reported
Studies not reported
Adults with at least one non-restorable or failing tooth undergoing immediate implant placement (within 24 h of extraction)dynamic CAIS (dCAIS)half-guided static CAIS (HG-sCAIS)Angular deviation between planned and actual implant position
Immediate placement; CBCT after surgery · Clinical studies of immediate implant placement; accuracy assessed by CBCT superimposition · Post hoc sensitivity NMA: RCTs plus low- and moderate-risk non-randomized studies (contrast-based frequentist, Tables S7, S10, S13)
MD 0.1 [-2.74, 2.93]
GRADE not reported
Studies not reported
Adults with at least one non-restorable or failing tooth undergoing immediate implant placement (within 24 h of extraction)dynamic CAIS (dCAIS)half-guided static CAIS (HG-sCAIS)Linear deviation at the implant platform
Immediate placement; CBCT after surgery · Clinical studies of immediate implant placement; accuracy assessed by CBCT superimposition · Post hoc sensitivity NMA: RCT-only (contrast-based frequentist, Tables S16, S19, S22)
MD -0.01 [-0.75, 0.73]
GRADE not reported
Studies not reported
Adults with at least one non-restorable or failing tooth undergoing immediate implant placement (within 24 h of extraction)dynamic CAIS (dCAIS)half-guided static CAIS (HG-sCAIS)Linear deviation at the implant platform
Immediate placement; CBCT after surgery · Clinical studies of immediate implant placement; accuracy assessed by CBCT superimposition · Primary mixed-effects NMA, pairwise contrast with FDR-adjusted p (Table S2)
MD -0.428 [-0.7, -0.156]
Low
Downgraded: publication bias
0 studies
Adults with at least one non-restorable or failing tooth undergoing immediate implant placement (within 24 h of extraction)dynamic CAIS (dCAIS)half-guided static CAIS (HG-sCAIS)Linear deviation at the implant apex
Immediate placement; CBCT after surgery · Clinical studies of immediate implant placement; accuracy assessed by CBCT superimposition · Primary mixed-effects NMA, pairwise contrast with FDR-adjusted p (Table S2)
MD -0.819 [-1.801, -0.163]
Low
Downgraded: publication bias
0 studies
Adults with at least one non-restorable or failing tooth undergoing immediate implant placement (within 24 h of extraction)dynamic CAIS (dCAIS)half-guided static CAIS (HG-sCAIS)Linear deviation at the implant apex
Immediate placement; CBCT after surgery · Clinical studies of immediate implant placement; accuracy assessed by CBCT superimposition · Post hoc sensitivity NMA: RCTs plus low- and moderate-risk non-randomized studies (contrast-based frequentist, Tables S7, S10, S13)
Unresolved: the two extractors disagree on this row.
MD -1.144 [-1.676, -0.613]
GRADE not reported
Studies not reported
Adults with at least one non-restorable or failing tooth undergoing immediate implant placement (within 24 h of extraction)dynamic CAIS (dCAIS)half-guided static CAIS (HG-sCAIS)Angular deviation between planned and actual implant position
Immediate placement; CBCT after surgery · Clinical studies of immediate implant placement; accuracy assessed by CBCT superimposition · Post hoc sensitivity NMA: RCT-only (contrast-based frequentist, Tables S16, S19, S22)
MD 2.88 [-1.79, 7.54]
GRADE not reported
Studies not reported
Adults with at least one non-restorable or failing tooth undergoing immediate implant placement (within 24 h of extraction)dynamic CAIS (dCAIS)half-guided static CAIS (HG-sCAIS)Linear deviation at the implant platform
Immediate placement; CBCT after surgery · Clinical studies of immediate implant placement; accuracy assessed by CBCT superimposition · Post hoc sensitivity NMA: RCTs plus low- and moderate-risk non-randomized studies (contrast-based frequentist, Tables S7, S10, S13)
MD -0.479 [-0.662, -0.296]
GRADE not reported
Studies not reported
Adults with at least one non-restorable or failing tooth undergoing immediate implant placement (within 24 h of extraction)dynamic CAIS (dCAIS)half-guided static CAIS (HG-sCAIS)Angular deviation between planned and actual implant position
Immediate placement; CBCT after surgery · Clinical studies of immediate implant placement; accuracy assessed by CBCT superimposition · Primary mixed-effects NMA, pairwise contrast with FDR-adjusted p (Table S2)
MD -0.49 [-1.87, 0.89]
Low
Downgraded: publication bias
0 studies
Adults with at least one non-restorable or failing tooth undergoing immediate implant placement (within 24 h of extraction)robotic CAIS (rCAIS)fully-guided static CAIS (FG-sCAIS)Linear deviation at the implant platform
Immediate placement; CBCT after surgery · Clinical studies of immediate implant placement; accuracy assessed by CBCT superimposition · Primary mixed-effects NMA, pairwise contrast with FDR-adjusted p (Table S2)
MD -0.148 [-0.398, 0.102]
Low
Downgraded: publication bias
0 studies
Adults with at least one non-restorable or failing tooth undergoing immediate implant placement (within 24 h of extraction)robotic CAIS (rCAIS)fully-guided static CAIS (FG-sCAIS)Linear deviation at the implant platform
Immediate placement; CBCT after surgery · Clinical studies of immediate implant placement; accuracy assessed by CBCT superimposition · Post hoc sensitivity NMA: RCTs plus low- and moderate-risk non-randomized studies (contrast-based frequentist, Tables S7, S10, S13)
MD -0.1 [-0.28, 0.08]
GRADE not reported
Studies not reported
Adults with at least one non-restorable or failing tooth undergoing immediate implant placement (within 24 h of extraction)robotic CAIS (rCAIS)fully-guided static CAIS (FG-sCAIS)Angular deviation between planned and actual implant position
Immediate placement; CBCT after surgery · Clinical studies of immediate implant placement; accuracy assessed by CBCT superimposition · Primary mixed-effects NMA, pairwise contrast with FDR-adjusted p (Table S2)
MD -1.84 [-2.94, -0.73]
Low
Downgraded: publication bias
0 studies
Adults with at least one non-restorable or failing tooth undergoing immediate implant placement (within 24 h of extraction)robotic CAIS (rCAIS)fully-guided static CAIS (FG-sCAIS)Linear deviation at the implant apex
Immediate placement; CBCT after surgery · Clinical studies of immediate implant placement; accuracy assessed by CBCT superimposition · Post hoc sensitivity NMA: RCTs plus low- and moderate-risk non-randomized studies (contrast-based frequentist, Tables S7, S10, S13)
MD -0.29 [-0.89, 0.324]
GRADE not reported
Studies not reported
Adults with at least one non-restorable or failing tooth undergoing immediate implant placement (within 24 h of extraction)robotic CAIS (rCAIS)fully-guided static CAIS (FG-sCAIS)Linear deviation at the implant apex
Immediate placement; CBCT after surgery · Clinical studies of immediate implant placement; accuracy assessed by CBCT superimposition · Primary mixed-effects NMA, pairwise contrast with FDR-adjusted p (Table S2)
MD -0.427 [-1.242, 0.389]
Low
Downgraded: publication bias
0 studies
Adults with at least one non-restorable or failing tooth undergoing immediate implant placement (within 24 h of extraction)robotic CAIS (rCAIS)fully-guided static CAIS (FG-sCAIS)Angular deviation between planned and actual implant position
Immediate placement; CBCT after surgery · Clinical studies of immediate implant placement; accuracy assessed by CBCT superimposition · Post hoc sensitivity NMA: RCTs plus low- and moderate-risk non-randomized studies (contrast-based frequentist, Tables S7, S10, S13)
MD -1.54 [-4.82, 1.74]
GRADE not reported
Studies not reported
Adults with at least one non-restorable or failing tooth undergoing immediate implant placement (within 24 h of extraction)robotic CAIS (rCAIS)fully-guided static CAIS (FG-sCAIS)Implant placement accuracy (angular, platform and apex deviation)
Clinical studies of immediate implant placement; accuracy assessed by CBCT superimposition · RCT-only network
No RCT of robotic CAIS was available, so rCAIS was not included in the RCT-only network meta-analysis
No studies found
0 studies
Adults with at least one non-restorable or failing tooth undergoing immediate implant placement (within 24 h of extraction)robotic CAIS (rCAIS)half-guided static CAIS (HG-sCAIS)Angular deviation between planned and actual implant position
Immediate placement; CBCT after surgery · Clinical studies of immediate implant placement; accuracy assessed by CBCT superimposition · Primary mixed-effects NMA, pairwise contrast with FDR-adjusted p (Table S2)
MD -1.54 [-2.94, -0.15]
Low
Downgraded: publication bias
1 study
Adults with at least one non-restorable or failing tooth undergoing immediate implant placement (within 24 h of extraction)robotic CAIS (rCAIS)half-guided static CAIS (HG-sCAIS)Linear deviation at the implant platform
Immediate placement; CBCT after surgery · Clinical studies of immediate implant placement; accuracy assessed by CBCT superimposition · Post hoc sensitivity NMA: RCTs plus low- and moderate-risk non-randomized studies (contrast-based frequentist, Tables S7, S10, S13)
MD -0.404 [-0.564, -0.243]
GRADE not reported
Studies not reported
Adults with at least one non-restorable or failing tooth undergoing immediate implant placement (within 24 h of extraction)robotic CAIS (rCAIS)half-guided static CAIS (HG-sCAIS)Linear deviation at the implant platform
Immediate placement; CBCT after surgery · Clinical studies of immediate implant placement; accuracy assessed by CBCT superimposition · Primary mixed-effects NMA, pairwise contrast with FDR-adjusted p (Table S2)
MD -0.411 [-0.672, -0.151]
Low
Downgraded: publication bias
1 study
Adults with at least one non-restorable or failing tooth undergoing immediate implant placement (within 24 h of extraction)robotic CAIS (rCAIS)half-guided static CAIS (HG-sCAIS)Linear deviation at the implant apex
Immediate placement; CBCT after surgery · Clinical studies of immediate implant placement; accuracy assessed by CBCT superimposition · Post hoc sensitivity NMA: RCTs plus low- and moderate-risk non-randomized studies (contrast-based frequentist, Tables S7, S10, S13)
MD -0.576 [-1.106, -0.046]
GRADE not reported
Studies not reported
Adults with at least one non-restorable or failing tooth undergoing immediate implant placement (within 24 h of extraction)robotic CAIS (rCAIS)half-guided static CAIS (HG-sCAIS)Linear deviation at the implant apex
Immediate placement; CBCT after surgery · Clinical studies of immediate implant placement; accuracy assessed by CBCT superimposition · Primary mixed-effects NMA, pairwise contrast with FDR-adjusted p (Table S2)
MD -0.698 [-1.612, 0.216]
Low
Downgraded: publication bias
1 study
Adults with at least one non-restorable or failing tooth undergoing immediate implant placement (within 24 h of extraction)robotic CAIS (rCAIS)half-guided static CAIS (HG-sCAIS)Implant placement accuracy (angular, platform and apex deviation)
Clinical studies of immediate implant placement; accuracy assessed by CBCT superimposition · RCT-only network
No RCT of robotic CAIS was available, so rCAIS was not included in the RCT-only network meta-analysis
No studies found
0 studies
Adults with at least one non-restorable or failing tooth undergoing immediate implant placement (within 24 h of extraction)robotic CAIS (rCAIS)half-guided static CAIS (HG-sCAIS)Angular deviation between planned and actual implant position
Immediate placement; CBCT after surgery · Clinical studies of immediate implant placement; accuracy assessed by CBCT superimposition · Post hoc sensitivity NMA: RCTs plus low- and moderate-risk non-randomized studies (contrast-based frequentist, Tables S7, S10, S13)
MD -1.48 [-4.53, 1.57]
GRADE not reported
Studies not reported
Adults with at least one non-restorable or failing tooth undergoing immediate implant placement (within 24 h of extraction)dynamic CAIS (dCAIS)robotic CAIS (rCAIS)Implant placement accuracy (angular, platform and apex deviation)
Clinical studies of immediate implant placement; accuracy assessed by CBCT superimposition · RCT-only network
No RCT of robotic CAIS was available, so rCAIS was not included in the RCT-only network meta-analysis
No studies found
0 studies
Adults with at least one non-restorable or failing tooth undergoing immediate implant placement (within 24 h of extraction)dynamic CAIS (dCAIS)robotic CAIS (rCAIS)Linear deviation at the implant platform
Immediate placement; CBCT after surgery · Clinical studies of immediate implant placement; accuracy assessed by CBCT superimposition · Primary mixed-effects NMA, pairwise contrast with FDR-adjusted p (Table S2)
MD -0.017 [-0.272, 0.238]
Low
Downgraded: publication bias
0 studies
Adults with at least one non-restorable or failing tooth undergoing immediate implant placement (within 24 h of extraction)dynamic CAIS (dCAIS)robotic CAIS (rCAIS)Linear deviation at the implant apex
Immediate placement; CBCT after surgery · Clinical studies of immediate implant placement; accuracy assessed by CBCT superimposition · Primary mixed-effects NMA, pairwise contrast with FDR-adjusted p (Table S2)
MD -0.12 [-0.94, 0.699]
Low
Downgraded: publication bias
0 studies
Adults with at least one non-restorable or failing tooth undergoing immediate implant placement (within 24 h of extraction)dynamic CAIS (dCAIS)robotic CAIS (rCAIS)Angular deviation between planned and actual implant position
Immediate placement; CBCT after surgery · Clinical studies of immediate implant placement; accuracy assessed by CBCT superimposition · Post hoc sensitivity NMA: RCTs plus low- and moderate-risk non-randomized studies (contrast-based frequentist, Tables S7, S10, S13)
MD 1.57 [-2.04, 5.18]
GRADE not reported
Studies not reported
Adults with at least one non-restorable or failing tooth undergoing immediate implant placement (within 24 h of extraction)dynamic CAIS (dCAIS)robotic CAIS (rCAIS)Linear deviation at the implant platform
Immediate placement; CBCT after surgery · Clinical studies of immediate implant placement; accuracy assessed by CBCT superimposition · Post hoc sensitivity NMA: RCTs plus low- and moderate-risk non-randomized studies (contrast-based frequentist, Tables S7, S10, S13)
MD -0.075 [-0.246, 0.096]
GRADE not reported
Studies not reported
Adults with at least one non-restorable or failing tooth undergoing immediate implant placement (within 24 h of extraction)dynamic CAIS (dCAIS)robotic CAIS (rCAIS)Linear deviation at the implant apex
Immediate placement; CBCT after surgery · Clinical studies of immediate implant placement; accuracy assessed by CBCT superimposition · Post hoc sensitivity NMA: RCTs plus low- and moderate-risk non-randomized studies (contrast-based frequentist, Tables S7, S10, S13)
MD -0.286 [-0.912, 0.341]
GRADE not reported
Studies not reported
Adults with at least one non-restorable or failing tooth undergoing immediate implant placement (within 24 h of extraction)dynamic CAIS (dCAIS)robotic CAIS (rCAIS)Angular deviation between planned and actual implant position
Immediate placement; CBCT after surgery · Clinical studies of immediate implant placement; accuracy assessed by CBCT superimposition · Primary mixed-effects NMA, pairwise contrast with FDR-adjusted p (Table S2)
MD 1.05 [0.06, 2.15]
Low
Downgraded: publication bias
0 studies
Adults with at least one non-restorable or failing tooth undergoing immediate implant placement (within 24 h of extraction)fully-guided static CAIS (FG-sCAIS)half-guided static CAIS (HG-sCAIS)Linear deviation at the implant apex
Immediate placement; CBCT after surgery · Clinical studies of immediate implant placement; accuracy assessed by CBCT superimposition · Post hoc sensitivity NMA: RCT-only (contrast-based frequentist, Tables S16, S19, S22)
MD 0.53 [-0.583, 1.643]
GRADE not reported
Studies not reported
Adults with at least one non-restorable or failing tooth undergoing immediate implant placement (within 24 h of extraction)fully-guided static CAIS (FG-sCAIS)half-guided static CAIS (HG-sCAIS)Linear deviation at the implant platform
Immediate placement; CBCT after surgery · Clinical studies of immediate implant placement; accuracy assessed by CBCT superimposition · Post hoc sensitivity NMA: RCTs plus low- and moderate-risk non-randomized studies (contrast-based frequentist, Tables S7, S10, S13)
MD -0.303 [-0.479, -0.127]
GRADE not reported
Studies not reported
Adults with at least one non-restorable or failing tooth undergoing immediate implant placement (within 24 h of extraction)fully-guided static CAIS (FG-sCAIS)half-guided static CAIS (HG-sCAIS)Linear deviation at the implant platform
Immediate placement; CBCT after surgery · Clinical studies of immediate implant placement; accuracy assessed by CBCT superimposition · Post hoc sensitivity NMA: RCT-only (contrast-based frequentist, Tables S16, S19, S22)
MD -0.08 [-0.73, 0.57]
GRADE not reported
Studies not reported
Adults with at least one non-restorable or failing tooth undergoing immediate implant placement (within 24 h of extraction)fully-guided static CAIS (FG-sCAIS)half-guided static CAIS (HG-sCAIS)Angular deviation between planned and actual implant position
Immediate placement; CBCT after surgery · Clinical studies of immediate implant placement; accuracy assessed by CBCT superimposition · Primary mixed-effects NMA, pairwise contrast with FDR-adjusted p (Table S2)
MD 0.3 [-1.09, 1.68]
Low
Downgraded: publication bias
2 studies
Adults with at least one non-restorable or failing tooth undergoing immediate implant placement (within 24 h of extraction)fully-guided static CAIS (FG-sCAIS)half-guided static CAIS (HG-sCAIS)Linear deviation at the implant apex
Immediate placement; CBCT after surgery · Clinical studies of immediate implant placement; accuracy assessed by CBCT superimposition · Post hoc sensitivity NMA: RCTs plus low- and moderate-risk non-randomized studies (contrast-based frequentist, Tables S7, S10, S13)
MD -0.29 [-0.739, 0.158]
GRADE not reported
Studies not reported
Adults with at least one non-restorable or failing tooth undergoing immediate implant placement (within 24 h of extraction)fully-guided static CAIS (FG-sCAIS)half-guided static CAIS (HG-sCAIS)Linear deviation at the implant apex
Immediate placement; CBCT after surgery · Clinical studies of immediate implant placement; accuracy assessed by CBCT superimposition · Primary mixed-effects NMA, pairwise contrast with FDR-adjusted p (Table S2)
MD -0.272 [-1.266, 0.722]
Low
Downgraded: publication bias
2 studies
Adults with at least one non-restorable or failing tooth undergoing immediate implant placement (within 24 h of extraction)fully-guided static CAIS (FG-sCAIS)half-guided static CAIS (HG-sCAIS)Linear deviation at the implant platform
Immediate placement; CBCT after surgery · Clinical studies of immediate implant placement; accuracy assessed by CBCT superimposition · Primary mixed-effects NMA, pairwise contrast with FDR-adjusted p (Table S2)
MD -0.263 [-0.531, -0.005]
Low
Downgraded: publication bias
2 studies
Adults with at least one non-restorable or failing tooth undergoing immediate implant placement (within 24 h of extraction)fully-guided static CAIS (FG-sCAIS)half-guided static CAIS (HG-sCAIS)Angular deviation between planned and actual implant position
Immediate placement; CBCT after surgery · Clinical studies of immediate implant placement; accuracy assessed by CBCT superimposition · Post hoc sensitivity NMA: RCT-only (contrast-based frequentist, Tables S16, S19, S22)
MD 1.76 [-2.3, 5.82]
GRADE not reported
Studies not reported
Adults with at least one non-restorable or failing tooth undergoing immediate implant placement (within 24 h of extraction)fully-guided static CAIS (FG-sCAIS)half-guided static CAIS (HG-sCAIS)Angular deviation between planned and actual implant position
Immediate placement; CBCT after surgery · Clinical studies of immediate implant placement; accuracy assessed by CBCT superimposition · Post hoc sensitivity NMA: RCTs plus low- and moderate-risk non-randomized studies (contrast-based frequentist, Tables S7, S10, S13)
MD 0.07 [-2.57, 2.71]
GRADE not reported
Studies not reported
Adults undergoing immediate implant placement (within 24 h of extraction)Low vs moderate risk of bias (study level)Moderate risk of biasAngular deviation between planned and actual implant position
Immediately after planning/surgery; accuracy by superimposition of post-operative CBCT (or intraoral scan) on the plan · Clinical studies of immediate implant placement · Study-level covariate in primary mixed-effects NMA (Table 5)
MD -0.45
GRADE not reported
Studies not reported
Adults with at least one non-restorable or failing tooth undergoing immediate implant placement (within 24 h of extraction)freehand (FH) placementNone (model-adjusted marginal mean for each protocol)Linear deviation at the implant apex
Clinical studies of immediate implant placement; accuracy assessed by CBCT superimposition · Adjusted estimated marginal mean (Table 6)
Mean deviation 1.87 [1.511, 2.247]
GRADE not reported
Studies not reported
Adults with at least one non-restorable or failing tooth undergoing immediate implant placement (within 24 h of extraction)freehand (FH) placementNone (unadjusted pooled mean for each protocol)Linear deviation at the implant platform
Clinical studies of immediate implant placement; accuracy assessed by CBCT superimposition · Unweighted pooled mean (Table S3)
Mean deviation 1.34
GRADE not reported
4 studies
Adults undergoing immediate implant placement (within 24 h of extraction)Low vs moderate risk of bias (study level)Moderate risk of biasPlatform (entry point) linear deviation between planned and actual implant position
Immediately after planning/surgery; accuracy by superimposition of post-operative CBCT (or intraoral scan) on the plan · Clinical studies of immediate implant placement · Study-level covariate in primary mixed-effects NMA (Table 5)
MD -0.076
GRADE not reported
Studies not reported
Adults undergoing immediate implant placement (within 24 h of extraction)Low vs moderate risk of bias (study level)Moderate risk of biasApex linear deviation between planned and actual implant position
Immediately after planning/surgery; accuracy by superimposition of post-operative CBCT (or intraoral scan) on the plan · Clinical studies of immediate implant placement · Study-level covariate in primary mixed-effects NMA (Table 5)
MD 0.192
GRADE not reported
Studies not reported
Adults with at least one non-restorable or failing tooth undergoing immediate implant placement (within 24 h of extraction)freehand (FH) placementNone (model-adjusted marginal mean for each protocol)Angular deviation between planned and actual implant position
Clinical studies of immediate implant placement; accuracy assessed by CBCT superimposition · Adjusted estimated marginal mean (Table 6)
Mean deviation 4.15 [3.54, 4.76]
GRADE not reported
Studies not reported
Adults with at least one non-restorable or failing tooth undergoing immediate implant placement (within 24 h of extraction)freehand (FH) placementNone (unadjusted pooled mean for each protocol)Angular deviation between planned and actual implant position
Clinical studies of immediate implant placement; accuracy assessed by CBCT superimposition · Unweighted pooled mean (Table S3)
Mean deviation 5.08
GRADE not reported
5 studies
Adults with at least one non-restorable or failing tooth undergoing immediate implant placement (within 24 h of extraction)freehand (FH) placementNone (unadjusted pooled mean for each protocol)Linear deviation at the implant apex
Clinical studies of immediate implant placement; accuracy assessed by CBCT superimposition · Unweighted pooled mean (Table S3)
Mean deviation 1.82
GRADE not reported
4 studies
Adults with at least one non-restorable or failing tooth undergoing immediate implant placement (within 24 h of extraction)freehand (FH) placementNone (model-adjusted marginal mean for each protocol)Linear deviation at the implant platform
Clinical studies of immediate implant placement; accuracy assessed by CBCT superimposition · Adjusted estimated marginal mean (Table 6)
Mean deviation 1.26 [1.135, 1.4]
GRADE not reported
Studies not reported
Adults with at least one non-restorable or failing tooth undergoing immediate implant placement (within 24 h of extraction)half-guided static CAIS (HG-sCAIS)None (model-adjusted marginal mean for each protocol)Linear deviation at the implant apex
Clinical studies of immediate implant placement; accuracy assessed by CBCT superimposition · Adjusted estimated marginal mean (Table 6)
Mean deviation 0.65 [0.155, 1.145]
GRADE not reported
Studies not reported
Adults undergoing immediate implant placement (within 24 h of extraction)High vs moderate risk of bias (study level)Moderate risk of biasPlatform (entry point) linear deviation between planned and actual implant position
Immediately after planning/surgery; accuracy by superimposition of post-operative CBCT (or intraoral scan) on the plan · Clinical studies of immediate implant placement · Study-level covariate in primary mixed-effects NMA (Table 5)
MD -0.265
GRADE not reported
Studies not reported
Adults with at least one non-restorable or failing tooth undergoing immediate implant placement (within 24 h of extraction)half-guided static CAIS (HG-sCAIS)None (unadjusted pooled mean for each protocol)Angular deviation between planned and actual implant position
Clinical studies of immediate implant placement; accuracy assessed by CBCT superimposition · Unweighted pooled mean (Table S3)
Mean deviation 2.54
GRADE not reported
4 studies
Adults with at least one non-restorable or failing tooth undergoing immediate implant placement (within 24 h of extraction)half-guided static CAIS (HG-sCAIS)None (model-adjusted marginal mean for each protocol)Linear deviation at the implant platform
Clinical studies of immediate implant placement; accuracy assessed by CBCT superimposition · Adjusted estimated marginal mean (Table 6)
Mean deviation 0.95 [0.763, 1.139]
GRADE not reported
Studies not reported
Adults with at least one non-restorable or failing tooth undergoing immediate implant placement (within 24 h of extraction)half-guided static CAIS (HG-sCAIS)None (unadjusted pooled mean for each protocol)Linear deviation at the implant apex
Clinical studies of immediate implant placement; accuracy assessed by CBCT superimposition · Unweighted pooled mean (Table S3)
Mean deviation 1.22
GRADE not reported
4 studies
Adults undergoing immediate implant placement (within 24 h of extraction)High vs moderate risk of bias (study level)Moderate risk of biasAngular deviation between planned and actual implant position
Immediately after planning/surgery; accuracy by superimposition of post-operative CBCT (or intraoral scan) on the plan · Clinical studies of immediate implant placement · Study-level covariate in primary mixed-effects NMA (Table 5)
MD -1.38
GRADE not reported
Studies not reported
Adults with at least one non-restorable or failing tooth undergoing immediate implant placement (within 24 h of extraction)half-guided static CAIS (HG-sCAIS)None (model-adjusted marginal mean for each protocol)Angular deviation between planned and actual implant position
Clinical studies of immediate implant placement; accuracy assessed by CBCT superimposition · Adjusted estimated marginal mean (Table 6)
Mean deviation 2.02 [1.18, 2.86]
GRADE not reported
Studies not reported
Adults undergoing immediate implant placement (within 24 h of extraction)High vs moderate risk of bias (study level)Moderate risk of biasApex linear deviation between planned and actual implant position
Immediately after planning/surgery; accuracy by superimposition of post-operative CBCT (or intraoral scan) on the plan · Clinical studies of immediate implant placement · Study-level covariate in primary mixed-effects NMA (Table 5)
MD -0.812
GRADE not reported
Studies not reported
Adults undergoing immediate implant placement (within 24 h of extraction)Maxilla percentage (per 1% increase)No increase in maxilla percentageAngular deviation between planned and actual implant position
Immediately after planning/surgery; accuracy by superimposition of post-operative CBCT (or intraoral scan) on the plan · Clinical studies of immediate implant placement · Study-level covariate in primary mixed-effects NMA (Table 5)
MD 0.0089
GRADE not reported
Studies not reported
Adults with at least one non-restorable or failing tooth undergoing immediate implant placement (within 24 h of extraction)fully-guided static CAIS (FG-sCAIS)None (model-adjusted marginal mean for each protocol)Linear deviation at the implant apex
Clinical studies of immediate implant placement; accuracy assessed by CBCT superimposition · Adjusted estimated marginal mean (Table 6)
Mean deviation 1.06 [0.65, 1.488]
GRADE not reported
Studies not reported
Adults with at least one non-restorable or failing tooth undergoing immediate implant placement (within 24 h of extraction)fully-guided static CAIS (FG-sCAIS)None (model-adjusted marginal mean for each protocol)Linear deviation at the implant platform
Clinical studies of immediate implant placement; accuracy assessed by CBCT superimposition · Adjusted estimated marginal mean (Table 6)
Mean deviation 0.72 [0.591, 0.857]
GRADE not reported
Studies not reported
Adults with at least one non-restorable or failing tooth undergoing immediate implant placement (within 24 h of extraction)fully-guided static CAIS (FG-sCAIS)None (model-adjusted marginal mean for each protocol)Angular deviation between planned and actual implant position
Clinical studies of immediate implant placement; accuracy assessed by CBCT superimposition · Adjusted estimated marginal mean (Table 6)
Mean deviation 2.32 [1.84, 2.79]
GRADE not reported
Studies not reported
Adults with at least one non-restorable or failing tooth undergoing immediate implant placement (within 24 h of extraction)fully-guided static CAIS (FG-sCAIS)None (unadjusted pooled mean for each protocol)Angular deviation between planned and actual implant position
Clinical studies of immediate implant placement; accuracy assessed by CBCT superimposition · Unweighted pooled mean (Table S3)
Mean deviation 2.72
GRADE not reported
8 studies
Adults with at least one non-restorable or failing tooth undergoing immediate implant placement (within 24 h of extraction)fully-guided static CAIS (FG-sCAIS)None (unadjusted pooled mean for each protocol)Linear deviation at the implant apex
Clinical studies of immediate implant placement; accuracy assessed by CBCT superimposition · Unweighted pooled mean (Table S3)
Mean deviation 1.34
GRADE not reported
7 studies
Adults undergoing immediate implant placement (within 24 h of extraction)Maxilla percentage (per 1% increase)No increase in maxilla percentagePlatform (entry point) linear deviation between planned and actual implant position
Immediately after planning/surgery; accuracy by superimposition of post-operative CBCT (or intraoral scan) on the plan · Clinical studies of immediate implant placement · Study-level covariate in primary mixed-effects NMA (Table 5)
MD -0.001
GRADE not reported
Studies not reported
Adults undergoing immediate implant placement (within 24 h of extraction)Maxilla percentage (per 1% increase)No increase in maxilla percentageApex linear deviation between planned and actual implant position
Immediately after planning/surgery; accuracy by superimposition of post-operative CBCT (or intraoral scan) on the plan · Clinical studies of immediate implant placement · Study-level covariate in primary mixed-effects NMA (Table 5)
MD 0.007
GRADE not reported
Studies not reported
Adults with at least one non-restorable or failing tooth undergoing immediate implant placement (within 24 h of extraction)fully-guided static CAIS (FG-sCAIS)None (unadjusted pooled mean for each protocol)Linear deviation at the implant platform
Clinical studies of immediate implant placement; accuracy assessed by CBCT superimposition · Unweighted pooled mean (Table S3)
Mean deviation 0.93
GRADE not reported
7 studies
Adults undergoing immediate implant placement (within 24 h of extraction)Anterior implant percentage (per 1% increase)No increase in anterior percentageAngular deviation between planned and actual implant position
Immediately after planning/surgery; accuracy by superimposition of post-operative CBCT (or intraoral scan) on the plan · Clinical studies of immediate implant placement · Study-level covariate in primary mixed-effects NMA (Table 5)
MD 0.02
GRADE not reported
Studies not reported
Adults with at least one non-restorable or failing tooth undergoing immediate implant placement (within 24 h of extraction)dynamic CAIS (dCAIS)None (model-adjusted marginal mean for each protocol)Linear deviation at the implant apex
Clinical studies of immediate implant placement; accuracy assessed by CBCT superimposition · Adjusted estimated marginal mean (Table 6)
Mean deviation 0.56 [0.313, 0.812]
GRADE not reported
Studies not reported
Adults undergoing immediate implant placement (within 24 h of extraction)Anterior implant percentage (per 1% increase)No increase in anterior percentageApex linear deviation between planned and actual implant position
Immediately after planning/surgery; accuracy by superimposition of post-operative CBCT (or intraoral scan) on the plan · Clinical studies of immediate implant placement · Study-level covariate in primary mixed-effects NMA (Table 5)
MD -0.002
GRADE not reported
Studies not reported
Adults with at least one non-restorable or failing tooth undergoing immediate implant placement (within 24 h of extraction)dynamic CAIS (dCAIS)None (unadjusted pooled mean for each protocol)Linear deviation at the implant apex
Clinical studies of immediate implant placement; accuracy assessed by CBCT superimposition · Unweighted pooled mean (Table S3)
Mean deviation 0.897
GRADE not reported
6 studies
Adults with at least one non-restorable or failing tooth undergoing immediate implant placement (within 24 h of extraction)dynamic CAIS (dCAIS)None (model-adjusted marginal mean for each protocol)Angular deviation between planned and actual implant position
Clinical studies of immediate implant placement; accuracy assessed by CBCT superimposition · Adjusted estimated marginal mean (Table 6)
Mean deviation 1.53 [1.08, 1.98]
GRADE not reported
Studies not reported
Adults with at least one non-restorable or failing tooth undergoing immediate implant placement (within 24 h of extraction)dynamic CAIS (dCAIS)None (unadjusted pooled mean for each protocol)Linear deviation at the implant platform
Clinical studies of immediate implant placement; accuracy assessed by CBCT superimposition · Unweighted pooled mean (Table S3)
Mean deviation 0.785
GRADE not reported
6 studies
Adults with at least one non-restorable or failing tooth undergoing immediate implant placement (within 24 h of extraction)dynamic CAIS (dCAIS)None (model-adjusted marginal mean for each protocol)Linear deviation at the implant platform
Clinical studies of immediate implant placement; accuracy assessed by CBCT superimposition · Adjusted estimated marginal mean (Table 6)
Mean deviation 0.55 [0.423, 0.687]
GRADE not reported
Studies not reported
Adults with at least one non-restorable or failing tooth undergoing immediate implant placement (within 24 h of extraction)dynamic CAIS (dCAIS)None (unadjusted pooled mean for each protocol)Angular deviation between planned and actual implant position
Clinical studies of immediate implant placement; accuracy assessed by CBCT superimposition · Unweighted pooled mean (Table S3)
Mean deviation 1.94
GRADE not reported
6 studies
Adults undergoing immediate implant placement (within 24 h of extraction)Anterior implant percentage (per 1% increase)No increase in anterior percentagePlatform (entry point) linear deviation between planned and actual implant position
Immediately after planning/surgery; accuracy by superimposition of post-operative CBCT (or intraoral scan) on the plan · Clinical studies of immediate implant placement · Study-level covariate in primary mixed-effects NMA (Table 5)
MD 0.0108
GRADE not reported
Studies not reported
Adults undergoing immediate implant placement (within 24 h of extraction)Open-ended sites (yes)Sites not open-endedAngular deviation between planned and actual implant position
Immediately after planning/surgery; accuracy by superimposition of post-operative CBCT (or intraoral scan) on the plan · Clinical studies of immediate implant placement · Study-level covariate in primary mixed-effects NMA (Table 5)
MD 1.59
GRADE not reported
Studies not reported
Adults undergoing immediate implant placement (within 24 h of extraction)Open-ended sites (yes)Sites not open-endedPlatform (entry point) linear deviation between planned and actual implant position
Immediately after planning/surgery; accuracy by superimposition of post-operative CBCT (or intraoral scan) on the plan · Clinical studies of immediate implant placement · Study-level covariate in primary mixed-effects NMA (Table 5)
MD 0.867
GRADE not reported
Studies not reported
Adults with at least one non-restorable or failing tooth undergoing immediate implant placement (within 24 h of extraction)robotic CAIS (rCAIS)None (unadjusted pooled mean for each protocol)Linear deviation at the implant platform
Clinical studies of immediate implant placement; accuracy assessed by CBCT superimposition · Unweighted pooled mean (Table S3)
Mean deviation 0.674
GRADE not reported
5 studies
Adults with at least one non-restorable or failing tooth undergoing immediate implant placement (within 24 h of extraction)robotic CAIS (rCAIS)None (unadjusted pooled mean for each protocol)Angular deviation between planned and actual implant position
Clinical studies of immediate implant placement; accuracy assessed by CBCT superimposition · Unweighted pooled mean (Table S3)
Mean deviation 1.39
GRADE not reported
5 studies
Adults with at least one non-restorable or failing tooth undergoing immediate implant placement (within 24 h of extraction)robotic CAIS (rCAIS)None (unadjusted pooled mean for each protocol)Linear deviation at the implant apex
Clinical studies of immediate implant placement; accuracy assessed by CBCT superimposition · Unweighted pooled mean (Table S3)
Mean deviation 0.694
GRADE not reported
5 studies
Adults with at least one non-restorable or failing tooth undergoing immediate implant placement (within 24 h of extraction)robotic CAIS (rCAIS)None (model-adjusted marginal mean for each protocol)Linear deviation at the implant apex
Clinical studies of immediate implant placement; accuracy assessed by CBCT superimposition · Adjusted estimated marginal mean (Table 6)
Mean deviation 0.45 [0.053, 0.849]
GRADE not reported
Studies not reported
Adults with at least one non-restorable or failing tooth undergoing immediate implant placement (within 24 h of extraction)robotic CAIS (rCAIS)None (model-adjusted marginal mean for each protocol)Linear deviation at the implant platform
Clinical studies of immediate implant placement; accuracy assessed by CBCT superimposition · Adjusted estimated marginal mean (Table 6)
Mean deviation 0.57 [0.387, 0.762]
GRADE not reported
Studies not reported
Adults with at least one non-restorable or failing tooth undergoing immediate implant placement (within 24 h of extraction)robotic CAIS (rCAIS)None (model-adjusted marginal mean for each protocol)Angular deviation between planned and actual implant position
Clinical studies of immediate implant placement; accuracy assessed by CBCT superimposition · Adjusted estimated marginal mean (Table 6)
Mean deviation 0.48 [-0.2, 1.17]
GRADE not reported
Studies not reported
Adults undergoing immediate implant placement (within 24 h of extraction)Open-ended sites (yes)Sites not open-endedApex linear deviation between planned and actual implant position
Immediately after planning/surgery; accuracy by superimposition of post-operative CBCT (or intraoral scan) on the plan · Clinical studies of immediate implant placement · Study-level covariate in primary mixed-effects NMA (Table 5)
MD 1.414
GRADE not reported
Studies not reported
Adults undergoing immediate implant placement (within 24 h of extraction)Case series designRCT designAngular deviation between planned and actual implant position
Immediately after planning/surgery; accuracy by superimposition of post-operative CBCT (or intraoral scan) on the plan · Clinical studies of immediate implant placement · Study-level covariate in primary mixed-effects NMA (Table 5)
MD -1.0287
GRADE not reported
Studies not reported
Adults undergoing immediate implant placement (within 24 h of extraction)Case series designRCT designApex linear deviation between planned and actual implant position
Immediately after planning/surgery; accuracy by superimposition of post-operative CBCT (or intraoral scan) on the plan · Clinical studies of immediate implant placement · Study-level covariate in primary mixed-effects NMA (Table 5)
MD -0.221
GRADE not reported
Studies not reported
Adults undergoing immediate implant placement (within 24 h of extraction)Case series designRCT designPlatform (entry point) linear deviation between planned and actual implant position
Immediately after planning/surgery; accuracy by superimposition of post-operative CBCT (or intraoral scan) on the plan · Clinical studies of immediate implant placement · Study-level covariate in primary mixed-effects NMA (Table 5)
MD -0.198
GRADE not reported
Studies not reported
Adults undergoing immediate implant placement (within 24 h of extraction)Retrospective designRCT designPlatform (entry point) linear deviation between planned and actual implant position
Immediately after planning/surgery; accuracy by superimposition of post-operative CBCT (or intraoral scan) on the plan · Clinical studies of immediate implant placement · Study-level covariate in primary mixed-effects NMA (Table 5)
MD -0.381
GRADE not reported
Studies not reported
Adults undergoing immediate implant placement (within 24 h of extraction)Retrospective designRCT designAngular deviation between planned and actual implant position
Immediately after planning/surgery; accuracy by superimposition of post-operative CBCT (or intraoral scan) on the plan · Clinical studies of immediate implant placement · Study-level covariate in primary mixed-effects NMA (Table 5)
MD -1.1707
GRADE not reported
Studies not reported
Adults undergoing immediate implant placement (within 24 h of extraction)Retrospective designRCT designApex linear deviation between planned and actual implant position
Immediately after planning/surgery; accuracy by superimposition of post-operative CBCT (or intraoral scan) on the plan · Clinical studies of immediate implant placement · Study-level covariate in primary mixed-effects NMA (Table 5)
MD -0.045
GRADE not reported
Studies not reported
Adults undergoing immediate implant placement (within 24 h of extraction)Robotic computer-assisted implant surgery (rCAIS)NoneApex linear deviation between planned and actual implant position
Immediately after planning/surgery; accuracy by superimposition of post-operative CBCT (or intraoral scan) on the plan · Clinical studies of immediate implant placement · Sensitivity NMA: RCTs plus low/moderate risk-of-bias non-randomized studies (random-effects, netmeta): P-score
P-score 0.749
GRADE not reported
Studies not reported
Adults undergoing immediate implant placement (within 24 h of extraction)Robotic computer-assisted implant surgery (rCAIS)NoneAngular deviation between planned and actual implant position
Immediately after planning/surgery; accuracy by superimposition of post-operative CBCT (or intraoral scan) on the plan · Clinical studies of immediate implant placement · Sensitivity NMA: RCTs plus low/moderate risk-of-bias non-randomized studies (random-effects, netmeta): P-score
P-score 0.863
GRADE not reported
Studies not reported
Adults undergoing immediate implant placement (within 24 h of extraction)Robotic computer-assisted implant surgery (rCAIS)NonePlatform (entry point) linear deviation between planned and actual implant position
Immediately after planning/surgery; accuracy by superimposition of post-operative CBCT (or intraoral scan) on the plan · Clinical studies of immediate implant placement · Sensitivity NMA: RCTs plus low/moderate risk-of-bias non-randomized studies (random-effects, netmeta): P-score
P-score 0.767
GRADE not reported
Studies not reported
Adults undergoing immediate implant placement (within 24 h of extraction)Dynamic computer-assisted implant surgery (dCAIS)NoneAngular deviation between planned and actual implant position
Immediately after planning/surgery; accuracy by superimposition of post-operative CBCT (or intraoral scan) on the plan · Clinical studies of immediate implant placement · Sensitivity NMA: RCT-only (random-effects, netmeta): P-score
P-score 0.428
GRADE not reported
Studies not reported
Adults undergoing immediate implant placement (within 24 h of extraction)Dynamic computer-assisted implant surgery (dCAIS)NonePlatform (entry point) linear deviation between planned and actual implant position
Immediately after planning/surgery; accuracy by superimposition of post-operative CBCT (or intraoral scan) on the plan · Clinical studies of immediate implant placement · Sensitivity NMA: RCTs plus low/moderate risk-of-bias non-randomized studies (random-effects, netmeta): P-score
P-score 0.95
GRADE not reported
Studies not reported
Adults undergoing immediate implant placement (within 24 h of extraction)Dynamic computer-assisted implant surgery (dCAIS)NoneAngular deviation between planned and actual implant position
Immediately after planning/surgery; accuracy by superimposition of post-operative CBCT (or intraoral scan) on the plan · Clinical studies of immediate implant placement · Sensitivity NMA: RCTs plus low/moderate risk-of-bias non-randomized studies (random-effects, netmeta): P-score
P-score 0.555
GRADE not reported
Studies not reported
Adults undergoing immediate implant placement (within 24 h of extraction)Dynamic computer-assisted implant surgery (dCAIS)NoneApex linear deviation between planned and actual implant position
Immediately after planning/surgery; accuracy by superimposition of post-operative CBCT (or intraoral scan) on the plan · Clinical studies of immediate implant placement · Sensitivity NMA: RCTs plus low/moderate risk-of-bias non-randomized studies (random-effects, netmeta): P-score
P-score 0.952
GRADE not reported
Studies not reported
Adults undergoing immediate implant placement (within 24 h of extraction)Dynamic computer-assisted implant surgery (dCAIS)NoneApex linear deviation between planned and actual implant position
Immediately after planning/surgery; accuracy by superimposition of post-operative CBCT (or intraoral scan) on the plan · Clinical studies of immediate implant placement · Sensitivity NMA: RCT-only (random-effects, netmeta): P-score
P-score 0.77
GRADE not reported
Studies not reported
Adults undergoing immediate implant placement (within 24 h of extraction)Dynamic computer-assisted implant surgery (dCAIS)NonePlatform (entry point) linear deviation between planned and actual implant position
Immediately after planning/surgery; accuracy by superimposition of post-operative CBCT (or intraoral scan) on the plan · Clinical studies of immediate implant placement · Sensitivity NMA: RCT-only (random-effects, netmeta): P-score
P-score 0.62
GRADE not reported
Studies not reported
Adults undergoing immediate implant placement (within 24 h of extraction)Fully guided static CAIS (FG-sCAIS)NoneAngular deviation between planned and actual implant position
Immediately after planning/surgery; accuracy by superimposition of post-operative CBCT (or intraoral scan) on the plan · Clinical studies of immediate implant placement · Sensitivity NMA: RCT-only (random-effects, netmeta): P-score
P-score 0.676
GRADE not reported
Studies not reported
Adults undergoing immediate implant placement (within 24 h of extraction)Fully guided static CAIS (FG-sCAIS)NonePlatform (entry point) linear deviation between planned and actual implant position
Immediately after planning/surgery; accuracy by superimposition of post-operative CBCT (or intraoral scan) on the plan · Clinical studies of immediate implant placement · Sensitivity NMA: RCT-only (random-effects, netmeta): P-score
P-score 0.75
GRADE not reported
Studies not reported
Adults undergoing immediate implant placement (within 24 h of extraction)Fully guided static CAIS (FG-sCAIS)NoneAngular deviation between planned and actual implant position
Immediately after planning/surgery; accuracy by superimposition of post-operative CBCT (or intraoral scan) on the plan · Clinical studies of immediate implant placement · Sensitivity NMA: RCTs plus low/moderate risk-of-bias non-randomized studies (random-effects, netmeta): P-score
P-score 0.539
GRADE not reported
Studies not reported
Adults undergoing immediate implant placement (within 24 h of extraction)Fully guided static CAIS (FG-sCAIS)NoneApex linear deviation between planned and actual implant position
Immediately after planning/surgery; accuracy by superimposition of post-operative CBCT (or intraoral scan) on the plan · Clinical studies of immediate implant placement · Sensitivity NMA: RCTs plus low/moderate risk-of-bias non-randomized studies (random-effects, netmeta): P-score
P-score 0.519
GRADE not reported
Studies not reported
Adults undergoing immediate implant placement (within 24 h of extraction)Fully guided static CAIS (FG-sCAIS)NoneApex linear deviation between planned and actual implant position
Immediately after planning/surgery; accuracy by superimposition of post-operative CBCT (or intraoral scan) on the plan · Clinical studies of immediate implant placement · Sensitivity NMA: RCT-only (random-effects, netmeta): P-score
P-score 0.41
GRADE not reported
Studies not reported
Adults undergoing immediate implant placement (within 24 h of extraction)Fully guided static CAIS (FG-sCAIS)NonePlatform (entry point) linear deviation between planned and actual implant position
Immediately after planning/surgery; accuracy by superimposition of post-operative CBCT (or intraoral scan) on the plan · Clinical studies of immediate implant placement · Sensitivity NMA: RCTs plus low/moderate risk-of-bias non-randomized studies (random-effects, netmeta): P-score
P-score 0.533
GRADE not reported
Studies not reported
Adults undergoing immediate implant placement (within 24 h of extraction)Half guided static CAIS (HG-sCAIS)NonePlatform (entry point) linear deviation between planned and actual implant position
Immediately after planning/surgery; accuracy by superimposition of post-operative CBCT (or intraoral scan) on the plan · Clinical studies of immediate implant placement · Sensitivity NMA: RCT-only (random-effects, netmeta): P-score
P-score 0.62
GRADE not reported
Studies not reported
Adults undergoing immediate implant placement (within 24 h of extraction)Half guided static CAIS (HG-sCAIS)NoneApex linear deviation between planned and actual implant position
Immediately after planning/surgery; accuracy by superimposition of post-operative CBCT (or intraoral scan) on the plan · Clinical studies of immediate implant placement · Sensitivity NMA: RCTs plus low/moderate risk-of-bias non-randomized studies (random-effects, netmeta): P-score
P-score 0.278
GRADE not reported
Studies not reported
Adults undergoing immediate implant placement (within 24 h of extraction)Half guided static CAIS (HG-sCAIS)NoneApex linear deviation between planned and actual implant position
Immediately after planning/surgery; accuracy by superimposition of post-operative CBCT (or intraoral scan) on the plan · Clinical studies of immediate implant placement · Sensitivity NMA: RCT-only (random-effects, netmeta): P-score
P-score 0.81
GRADE not reported
Studies not reported
Adults undergoing immediate implant placement (within 24 h of extraction)Half guided static CAIS (HG-sCAIS)NonePlatform (entry point) linear deviation between planned and actual implant position
Immediately after planning/surgery; accuracy by superimposition of post-operative CBCT (or intraoral scan) on the plan · Clinical studies of immediate implant placement · Sensitivity NMA: RCTs plus low/moderate risk-of-bias non-randomized studies (random-effects, netmeta): P-score
P-score 0.25
GRADE not reported
Studies not reported
Adults undergoing immediate implant placement (within 24 h of extraction)Half guided static CAIS (HG-sCAIS)NonePlatform (entry point) linear deviation between planned and actual implant position
Immediately after planning/surgery; accuracy by superimposition of post-operative CBCT (or intraoral scan) on the plan · Clinical studies of immediate implant placement · Unweighted pooled mean, no model adjustment (Table S3)
Unweighted pooled mean deviation 0.927
GRADE not reported
4 studies
Adults undergoing immediate implant placement (within 24 h of extraction)Half guided static CAIS (HG-sCAIS)NoneAngular deviation between planned and actual implant position
Immediately after planning/surgery; accuracy by superimposition of post-operative CBCT (or intraoral scan) on the plan · Clinical studies of immediate implant placement · Sensitivity NMA: RCTs plus low/moderate risk-of-bias non-randomized studies (random-effects, netmeta): P-score
P-score 0.542
GRADE not reported
Studies not reported
Adults undergoing immediate implant placement (within 24 h of extraction)Half guided static CAIS (HG-sCAIS)NoneAngular deviation between planned and actual implant position
Immediately after planning/surgery; accuracy by superimposition of post-operative CBCT (or intraoral scan) on the plan · Clinical studies of immediate implant placement · Sensitivity NMA: RCT-only (random-effects, netmeta): P-score
P-score 0.895
GRADE not reported
Studies not reported
Adults undergoing immediate implant placement (within 24 h of extraction)Freehand placement (FH)NonePlatform (entry point) linear deviation between planned and actual implant position
Immediately after planning/surgery; accuracy by superimposition of post-operative CBCT (or intraoral scan) on the plan · Clinical studies of immediate implant placement · Sensitivity NMA: RCTs plus low/moderate risk-of-bias non-randomized studies (random-effects, netmeta): P-score
P-score 0.001
GRADE not reported
Studies not reported
Adults undergoing immediate implant placement (within 24 h of extraction)Freehand placement (FH)NoneApex linear deviation between planned and actual implant position
Immediately after planning/surgery; accuracy by superimposition of post-operative CBCT (or intraoral scan) on the plan · Clinical studies of immediate implant placement · Sensitivity NMA: RCTs plus low/moderate risk-of-bias non-randomized studies (random-effects, netmeta): P-score
P-score 0.002
GRADE not reported
Studies not reported
Adults undergoing immediate implant placement (within 24 h of extraction)Freehand placement (FH)NoneAngular deviation between planned and actual implant position
Immediately after planning/surgery; accuracy by superimposition of post-operative CBCT (or intraoral scan) on the plan · Clinical studies of immediate implant placement · Sensitivity NMA: RCT-only (random-effects, netmeta): P-score
P-score 0.002
GRADE not reported
Studies not reported
Adults undergoing immediate implant placement (within 24 h of extraction)Freehand placement (FH)NonePlatform (entry point) linear deviation between planned and actual implant position
Immediately after planning/surgery; accuracy by superimposition of post-operative CBCT (or intraoral scan) on the plan · Clinical studies of immediate implant placement · Sensitivity NMA: RCT-only (random-effects, netmeta): P-score
P-score 0.01
GRADE not reported
Studies not reported
Adults undergoing immediate implant placement (within 24 h of extraction)Freehand placement (FH)NoneApex linear deviation between planned and actual implant position
Immediately after planning/surgery; accuracy by superimposition of post-operative CBCT (or intraoral scan) on the plan · Clinical studies of immediate implant placement · Sensitivity NMA: RCT-only (random-effects, netmeta): P-score
P-score 0.02
GRADE not reported
Studies not reported
Adults undergoing immediate implant placement (within 24 h of extraction)Freehand placement (FH)NoneAngular deviation between planned and actual implant position
Immediately after planning/surgery; accuracy by superimposition of post-operative CBCT (or intraoral scan) on the plan · Clinical studies of immediate implant placement · Sensitivity NMA: RCTs plus low/moderate risk-of-bias non-randomized studies (random-effects, netmeta): P-score
P-score 0.001
GRADE not reported
Studies not reported

Included primary studies 19

Open in Studies
StudyYearAlso included byOutcomes it informs hereTrial data
Li, Dai 2024
Accuracy of immediate anterior implantation using static and robotic computer-assisted implant surgery: A retrospective study.
PMID:38955260
20243 other reviewsnot statednot extracted yet
Feng 2022
Comparison of the accuracy of immediate implant placement using static and dynamic computer-assisted implant system in the esthetic zone…
PMID:36512162
20221 other reviewnot statednot extracted yet
Li, Zhao 2024
Accuracy of robotic computer-assisted implant surgery for immediate implant placement: A retrospective case series study.
PMID:39302731
20241 other reviewnot statednot extracted yet
Liu 2025
Accuracy and operation procedure of robotic computer-aided implant surgery.
PMID:39748004
20251 other reviewnot statednot extracted yet
Yang and Geng 2024
Clinical study of immediate implant placement in posterior maxillary region assisted by dynamic real-time navigation: A randomized…
PMID:39043292
20241 other reviewnot statednot extracted yet
Yang, Xu 2024
Accuracy of robotic-assisted surgery for immediate implant placement in posterior teeth: a retrospective case series.
PMID:39438946
20241 other reviewnot statednot extracted yet
Zhao 2024
Accuracy analysis of robotic-assisted immediate implant placement: A retrospective case series.
PMID:38734299
20241 other reviewnot statednot extracted yet
Albiero 2019
Accuracy of Computer-Guided Flapless Implant Surgery in Fully Edentulous Arches and in Edentulous Arches With Fresh Extraction Sockets.
PMID:31124822
2019this review onlynot statednot extracted yet
Alzoubi 2016
Accuracy Assessment of Immediate and Delayed Implant Placements Using CAD/CAM Surgical Guides.
PMID:27266995
2016this review onlynot statednot extracted yet
Battista 2022
Dynamic Navigation System for Immediate Implant Placement in the Maxillary Aesthetic Region
DOI:10.3390/app12115510
2022this review onlynot statednot extracted yet
Battista 2022
matched by author and year (probable)
NRthis review onlynot statednot extracted yet
Chandran 2023
Accuracy of freehand versus guided immediate implant placement: A randomized controlled trial.
PMID:37454788
2023this review onlynot statednot extracted yet
Chen 2020
Accuracy of Full-Guided and Half-Guided Surgical Templates in Anterior Immediate and Delayed Implantation: A Retrospective Study.
PMID:33374727
2020this review onlynot statednot extracted yet
Geng 2023
Clinical study of dynamic real-time navigation assisted immediate implant without flapping in the esthetic zone.
PMID:36064144
2023this review onlynot statednot extracted yet
Geng 2024
Immediate implant placement in the posterior mandibular region was assisted by dynamic real-time navigation: a retrospective study.
PMID:38336661
2024this review onlynot statednot extracted yet
Han 2021
Whole-Process Digitalization-Assisted Immediate Implant Placement and Immediate Restoration in the Aesthetic Zone: A Prospective Study.
PMID:34428195
2021this review onlynot statednot extracted yet
Kraft 2020
Impact of fully or partially guided surgery on the position of single implants immediately placed in maxillary incisor sockets: A…
PMID:32875722
2020this review onlynot statednot extracted yet
Mittal 2024
Comparison of accuracy between single posterior immediate and delayed implants placed using computer guided implant surgery and a digital…
PMID:38218708
2025this review onlynot statednot extracted yet
Wei 2022
Does machine-vision-assisted dynamic navigation improve the accuracy of digitally planned prosthetically guided immediate implant…
PMID:35652362
2022this review onlynot statednot extracted yet

Overlap with other reviews

Reviews that include the same primary studies are not independent evidence. Shared counts match studies by PMID, DOI or NCT, and otherwise by author and year (a probable match). Only the non-Cochrane dental reviews have study lists, so overlap with Cochrane reviews is not counted yet.

Review question

ElementPlanned (methods)Found (results)
PopulationAdults with at least one non-restorable or failing tooth requiring extraction and immediate implant placement within 24 hAdults with immediate implant placement (541 patients, 780 implants; n=18 studies)
InterventionStatic (sCAIS), dynamic (dCAIS) or robotic (rCAIS) computer-assisted implant surgery; static split into fully guided (FG) and half guided (HG)dCAIS (108 patients, 151 implants); rCAIS (76 patients, 93 implants); FG-sCAIS (130 patients, 218 implants); HG-sCAIS (91 patients, 130 implants)
ComparisonConventional freehand (FH) implant placementFreehand (136 patients, 188 implants)
OutcomesAccuracy: angular deviation, linear deviation at the implant platform and apex (planned vs actual position)Angular, platform and apex deviation (n=18)
Study designsRCTs, non-randomized controlled trials, prospective or retrospective cohort studies, prospective or retrospective case series6 RCTs, 2 prospective case series, 7 retrospective case series, 3 retrospective cohort studies (n=18)
TimingNot specifiedNot specified

AMSTAR 2 items

Two independent extractors rated each item. Their ratings are shown side by side because they have not been reconciled yet. The overall rating follows Shea et al. 2017: one critical flaw gives Low, more than one gives Critically Low.

ItemExtractor AExtractor BAgree
1Research question includes PICO componentsYesYesyes
2Protocol established before the reviewcriticalPartial YesPartial Yesyes
3Choice of study designs explainedNoNoyes
4Comprehensive literature searchcriticalPartial YesPartial Yesyes
5Study selection in duplicateYesYesyes
6Data extraction in duplicateYesYesyes
7List of excluded studies with reasonscriticalYesYesyes
8Included studies described in detailPartial YesPartial Yesyes
9Risk of bias assessed satisfactorilycriticalRCT: Yes · NRSI: Partial YesNRSI: Partial Yes · RCT: Yesno
10Funding of included studies reportedNoNoyes
11Appropriate meta-analysis methodscriticalRCT: Yes · NRSI: YesNRSI: Yes · RCT: Yesno
12Impact of risk of bias on the pooled resultsYesYesyes
13Risk of bias accounted for in interpretationcriticalYesYesyes
14Heterogeneity explainedYesYesyes
15Publication bias investigatedcriticalNoNoyes
16Conflicts of interest reportedYesYesyes
OverallLowLowyes