Non-Cochrane · intervention · PM41307329

Accuracy of Freehand, Static, and Dynamic Computer-Assisted Implant Placement: A Systematic Review and Meta-Analysis.

Reiff Florian Sebastian, Kroeger Annika, Roehling Stefan, et al. · Journal of periodontal research · 2026 · PubMed · doi:10.1111/jre.70047

Findings

30 findings

Population
Cadaver and resin model (in vitro) implant placement; partially or fully edentulous jaw modelsDynamic computer-assisted implant surgery (dCAIS)Static computer-assisted implant surgery (sCAIS)Global coronal deviation (mm)
In vitro (models)
MD 0.11 [-0.17, 0.39]
GRADE not reported
11 studies · 1086 participants
Cadaver and resin model (in vitro) implant placement; partially or fully edentulous jaw modelsDynamic computer-assisted implant surgery (dCAIS)Static computer-assisted implant surgery (sCAIS)Axial deviation (degrees)
In vitro (models)
MD -0.60 [-1.16, -0.05]
GRADE not reported
11 studies · 1086 participants
Cadaver and resin model (in vitro) implant placement; partially or fully edentulous jaw modelsDynamic computer-assisted implant surgery (dCAIS)Static computer-assisted implant surgery (sCAIS)Global apical deviation (mm)
In vitro (models)
MD -0.05 [-0.32, 0.23]
GRADE not reported
11 studies · 1086 participants
Cadaver and resin model (in vitro) implant placement; partially or fully edentulous jaw modelsStatic computer-assisted implant surgery (sCAIS)Freehand implant placementGlobal apical deviation (mm)
In vitro (models)
MD -0.76 [-1.09, -0.44]
GRADE not reported
11 studies · 846 participants
Cadaver and resin model (in vitro) implant placement; partially or fully edentulous jaw modelsStatic computer-assisted implant surgery (sCAIS)Freehand implant placementAxial deviation (degrees)
In vitro (models)
MD -2.85 [-3.71, -1.98]
GRADE not reported
11 studies · 846 participants
Cadaver and resin model (in vitro) implant placement; partially or fully edentulous jaw modelsStatic computer-assisted implant surgery (sCAIS)Freehand implant placementGlobal coronal deviation (mm)
In vitro (models)
MD -0.56 [-0.79, -0.33]
GRADE not reported
11 studies · 846 participants
Cadaver and resin model (in vitro) implant placement; partially or fully edentulous jaw modelsDynamic computer-assisted implant surgery (dCAIS)Freehand implant placementGlobal coronal deviation (mm)
In vitro (models)
MD -0.60 [-0.93, -0.27]
GRADE not reported
4 studies · 306 participants
Cadaver and resin model (in vitro) implant placement; partially or fully edentulous jaw modelsDynamic computer-assisted implant surgery (dCAIS)Freehand implant placementGlobal apical deviation (mm)
In vitro (models)
MD -0.91 [-1.25, -0.58]
GRADE not reported
4 studies · 306 participants
Cadaver and resin model (in vitro) implant placement; partially or fully edentulous jaw modelsDynamic computer-assisted implant surgery (dCAIS)Freehand implant placementAxial deviation (degrees)
In vitro (models)
MD -3.34 [-4.39, -2.29]
GRADE not reported
4 studies · 306 participants
Human patients (18 years or older) receiving dental implants in edentulous spacesDynamic computer-assisted implant surgery (dCAIS)Static computer-assisted implant surgery (sCAIS)Global coronal deviation (mm)
Clinical · All clinical studies
MD -0.03 [-0.16, 0.11]
GRADE not reported
10 studies · 643 participants
Human patients (18 years or older) receiving dental implants in edentulous spacesDynamic computer-assisted implant surgery (dCAIS)Static computer-assisted implant surgery (sCAIS)Axial deviation (degrees)
Clinical · All clinical studies
MD -0.09 [-0.66, 0.48]
GRADE not reported
10 studies · 643 participants
Human patients (18 years or older) receiving dental implants in edentulous spacesDynamic computer-assisted implant surgery (dCAIS)Static computer-assisted implant surgery (sCAIS)Global coronal deviation (mm)
Clinical · RCTs only
MD 0.08 [-0.04, 0.19]
GRADE not reported
5 studies · 284 participants
Human patients (18 years or older) receiving dental implants in edentulous spacesDynamic computer-assisted implant surgery (dCAIS)Static computer-assisted implant surgery (sCAIS)Global apical deviation (mm)
Clinical · RCTs only
MD -0.03 [-0.16, 0.11]
GRADE not reported
5 studies · 284 participants
Human patients (18 years or older) receiving dental implants in edentulous spacesDynamic computer-assisted implant surgery (dCAIS)Static computer-assisted implant surgery (sCAIS)Axial deviation (degrees)
Clinical · RCTs only
MD 0.32 [-0.22, 0.86]
GRADE not reported
5 studies · 284 participants
Human patients (18 years or older) receiving dental implants in edentulous spacesDynamic computer-assisted implant surgery (dCAIS)Static computer-assisted implant surgery (sCAIS)Global apical deviation (mm)
Clinical · All clinical studies
MD -0.24 [-0.48, 0.00]
GRADE not reported
10 studies · 643 participants
Human patients (18 years or older) receiving dental implants in edentulous spacesStatic computer-assisted implant surgery (sCAIS)Freehand implant placementGlobal apical deviation (mm)
Clinical · All clinical studies
MD -1.16 [-2.20, -0.12]
GRADE not reported
7 studies · 432 participants
Human patients (18 years or older) receiving dental implants in edentulous spacesStatic computer-assisted implant surgery (sCAIS)Freehand implant placementAxial deviation (degrees)
Clinical · All clinical studies
MD -4.25 [-5.28, -3.22]
GRADE not reported
7 studies · 432 participants
Human patients (18 years or older) receiving dental implants in edentulous spacesStatic computer-assisted implant surgery (sCAIS)Freehand implant placementAxial deviation (degrees)
Clinical · RCTs only
MD -3.69 [-4.31, -3.06]
GRADE not reported
5 studies · 327 participants
Human patients (18 years or older) receiving dental implants in edentulous spacesStatic computer-assisted implant surgery (sCAIS)Freehand implant placementGlobal coronal deviation (mm)
Clinical · RCTs only
MD -0.41 [-0.56, -0.27]
GRADE not reported
5 studies · 327 participants
Human patients (18 years or older) receiving dental implants in edentulous spacesStatic computer-assisted implant surgery (sCAIS)Freehand implant placementGlobal apical deviation (mm)
Clinical · RCTs only
MD -0.73 [-0.90, -0.56]
GRADE not reported
5 studies · 327 participants
Human patients (18 years or older) receiving dental implants in edentulous spacesStatic computer-assisted implant surgery (sCAIS)Freehand implant placementGlobal coronal deviation (mm)
Clinical · All clinical studies
MD -0.92 [-1.95, 0.10]
GRADE not reported
7 studies · 432 participants
Human patients (18 years or older) receiving dental implants in edentulous spacesDynamic computer-assisted implant surgery (dCAIS)Freehand implant placementGlobal coronal deviation (mm)
Clinical · All clinical studies
MD -1.18 [-2.28, -0.08]
GRADE not reported
6 studies · 440 participants
Human patients (18 years or older) receiving dental implants in edentulous spacesDynamic computer-assisted implant surgery (dCAIS)Freehand implant placementAxial deviation (degrees)
Clinical · RCTs only
MD -3.37 [-4.73, -2.01]
GRADE not reported
4 studies · 306 participants
Human patients (18 years or older) receiving dental implants in edentulous spacesDynamic computer-assisted implant surgery (dCAIS)Freehand implant placementGlobal coronal deviation (mm)
Clinical · RCTs only
MD -0.69 [-0.72, -0.66]
GRADE not reported
4 studies · 306 participants
Human patients (18 years or older) receiving dental implants in edentulous spacesDynamic computer-assisted implant surgery (dCAIS)Freehand implant placementAxial deviation (degrees)
Clinical · All clinical studies
MD -3.61 [-5.17, -2.04]
GRADE not reported
6 studies · 440 participants
Human patients (18 years or older) receiving dental implants in edentulous spacesDynamic computer-assisted implant surgery (dCAIS)Freehand implant placementGlobal apical deviation (mm)
Clinical · RCTs only
MD -0.74 [-0.86, -0.62]
GRADE not reported
4 studies · 306 participants
Human patients (18 years or older) receiving dental implants in edentulous spacesDynamic computer-assisted implant surgery (dCAIS)Freehand implant placementGlobal apical deviation (mm)
Clinical · All clinical studies
MD -1.47 [-2.88, -0.05]
GRADE not reported
6 studies · 440 participants
Animals (any species; at least 5 per group) receiving at least one titanium dental implantDynamic computer-assisted implant surgery (dCAIS)Static computer-assisted implant surgery (sCAIS)Transfer accuracy (axial, global coronal and global apical deviation)
Animal
no estimate extracted
No studies found
0 studies
Animals (any species; at least 5 per group) receiving at least one titanium dental implantStatic computer-assisted implant surgery (sCAIS)Freehand implant placementTransfer accuracy (axial, global coronal and global apical deviation)
Animal
no estimate extracted
No studies found
0 studies
Animals (any species; at least 5 per group) receiving at least one titanium dental implantDynamic computer-assisted implant surgery (dCAIS)Freehand implant placementTransfer accuracy (axial, global coronal and global apical deviation)
Animal
no estimate extracted
No studies found
0 studies

Included primary studies 37

Open in Studies
StudyYearAlso included byOutcomes it informs hereTrial data
Feng 2022
Comparison of the accuracy of immediate implant placement using static and dynamic computer-assisted implant system in the esthetic zone…
PMID:36512162
20221 other reviewnot statednot extracted yet
Yang 2024
Clinical study of immediate implant placement in posterior maxillary region assisted by dynamic real-time navigation: A randomized…
PMID:39043292
20241 other reviewnot statednot extracted yet
Abduo 2020
Accuracy of static computer-assisted implant placement in anterior and posterior sites by clinicians new to implant dentistry: in vitro…
PMID:32157478
2020this review onlynot statednot extracted yet
Abduo 2021
Accuracy of static computer-assisted implant placement in long span edentulous area by novice implant clinicians: A cross-sectional in…
PMID:33817957
2021this review onlynot statednot extracted yet
Abduo 2023
Accuracy of Static Computer- Assisted Implant Placement in Posterior Edentulous Areas with Different Levels of Tooth- Support by Novice…
PMID:37191579
2023this review onlynot statednot extracted yet
Abduo 2025
Accuracy of Static Computer-Assisted Implant Placement in Narrow Ridge by Novice Clinicians.
PMID:40073980
2025this review onlynot statednot extracted yet
Alevizakos 2019
A retrospective study of the accuracy of template-guided versus freehand implant placement: A nonradiologic method.
PMID:31227455
2019this review onlynot statednot extracted yet
Aydemir 2020
Accuracy of dental implant placement via dynamic navigation or the freehand method: A split-mouth randomized controlled clinical trial.
PMID:31829457
2020this review onlynot statednot extracted yet
Chen 2022
Does guided level (fully or partially) influence implant placement accuracy at post-extraction sockets and healed sites? An in vitro study.
PMID:35499656
2022this review onlynot statednot extracted yet
Deng 2025
Clinical study of dynamic navigation-assisted immediate implant placement in posterior maxillary alveolar bone defects.
PMID:40269826
2025this review onlynot statednot extracted yet
Fang 2024
Effect of Clinical Experience on Accuracy of Implant Placement Using Dynamic Navigation and Static Guidance: An In Vitro Study.
PMID:39231244
2024this review onlynot statednot extracted yet
Franchina 2020
Validation of an Intra-Oral Scan Method Versus Cone Beam Computed Tomography Superimposition to Assess the Accuracy between Planned and…
PMID:33542168
2020this review onlynot statednot extracted yet
Fu 2023
Accuracy and patient-centered results of static and dynamic computer-assisted implant surgery in edentulous jaws: a retrospective cohort…
PMID:37480368
2023this review onlynot statednot extracted yet
Guentsch 2021
Precision and trueness of implant placement with and without static surgical guides: An in vitro study.
PMID:32893013
2021this review onlynot statednot extracted yet
Kaewsiri 2019
The accuracy of static vs. dynamic computer-assisted implant surgery in single tooth space: A randomized controlled trial.
PMID:31060099
2019this review onlynot statednot extracted yet
Liu 2024
Placement accuracy and primary stability of implants in the esthetic zone using dynamic and static computer-assisted navigation: A…
PMID:36473750
2024this review onlynot statednot extracted yet
Mampilly 2023
Accuracy and Self-Confidence Level of Freehand Drilling and Dynamic Navigation System of Dental Implants: An In Vitro Study.
PMID:38161848
2023this review onlynot statednot extracted yet
Mediavilla Guzman 2019
Accuracy of Computer-Aided Dynamic Navigation Compared to Computer-Aided Static Navigation for Dental Implant Placement: An In Vitro Study.
PMID:31810351
2019this review onlynot statednot extracted yet
Okubo 2025
Clinical accuracy assessment of a dynamic navigation system and surgical guide using an oral appliance-secured patient tracker targeting…
PMID:40389762
2025this review onlynot statednot extracted yet
Pitman 2024
matched by author and year (probable)
NRthis review onlynot statednot extracted yet
Pruthi 2025
The Effect of Different Socket Morphologies of a Maxillary Central Incisor on the Accuracy of Immediate Implants Placed With Freehand or…
PMID:39963729
2025this review onlynot statednot extracted yet
Shusterman 2024
Accuracy of implant placement using a mixed reality-based dynamic navigation system versus static computer-assisted and freehand surgery:…
PMID:38734298
2024this review onlynot statednot extracted yet
Smitkarn 2019
The accuracy of single-tooth implants placed using fully digital-guided surgery and freehand implant surgery.
PMID:31241782
2019this review onlynot statednot extracted yet
Struwe 2023
Accuracy of a dynamic navigation system for dental implantation with two different workflows and intraoral markers compared to…
PMID:36626272
2023this review onlynot statednot extracted yet
Stunkel 2022
Accuracy of intraoral real-time navigation versus static, CAD/CAM-manufactured pilot drilling guides in dental implant surgery: an in…
PMID:36198996
2022this review onlynot statednot extracted yet
Taheri Otaghsara 2023
Accuracy of dental implant placement using static versus dynamic computer-assisted implant surgery: An in vitro study.
PMID:36948382
2023this review onlynot statednot extracted yet
Varga 2020
Guidance means accuracy: A randomized clinical trial on freehand versus guided dental implantation.
PMID:31958166
2020this review onlynot statednot extracted yet
Verma 2023
Cone Beam Computed Tomography-Based Evaluation of the Accuracy of Implant Surgery with Conventional (Free Hand) Implant Placement vs…
PMID:38105824
2023this review onlynot statednot extracted yet
Wang M 2022
Comparison of Implant Placement Accuracy in Healed and Fresh Extraction Sockets between Static and Dynamic Computer-Assisted Implant…
PMID:35454496
2022this review onlynot statednot extracted yet
Wang W 2023
Exploring training dental implant placement using static or dynamic devices among dental students.
PMID:35579548
2023this review onlynot statednot extracted yet
Werny 2025
Evaluation of the Accuracy, Surgical Time, and Learning Curve of Freehand, Static, and Dynamic Computer-Assisted Implant Surgery in an…
PMID:39835464
2025this review onlynot statednot extracted yet
Wu 2020
Accuracy of dynamic navigation compared to static surgical guide for dental implant placement.
PMID:33230662
2020this review onlynot statednot extracted yet
Yimarj 2020
Comparison of the accuracy of implant position for two-implants supported fixed dental prosthesis using static and dynamic…
PMID:32939934
2020this review onlynot statednot extracted yet
Yotpibulwong 2023
Accuracy of implant placement with a combined use of static and dynamic computer-assisted implant surgery in single tooth space: A…
PMID:36756684
2023this review onlynot statednot extracted yet
Younis 2024
Accuracy of dynamic navigation compared to static surgical guides and the freehand approach in implant placement: a prospective clinical…
PMID:38745297
2024this review onlynot statednot extracted yet
Zhang 2025
Dynamic navigation-assisted flapless implant placement in the posterior mandible: a retrospective and comparative study.
PMID:39955224
2025this review onlynot statednot extracted yet
Zhou 2021
Comparison of the accuracy of dental implant placement using static and dynamic computer-assisted systems: an in vitro study.
PMID:33307210
2021this review onlynot statednot extracted yet

Overlap with other reviews

Reviews that include the same primary studies are not independent evidence. Shared counts match studies by PMID, DOI or NCT, and otherwise by author and year (a probable match). Only the non-Cochrane dental reviews have study lists, so overlap with Cochrane reviews is not counted yet.

Review question

ElementPlanned (methods)Found (results)
PopulationPICO 1: cadaver and in vitro (resin) models of edentulous jaws (at least 10 models, 30 implants); PICO 2: patients aged 18 years or older with edentulous space, at least 10 patients and 30 implants; PICO 3: animals (at least 5 per group)PICO 1: in vitro models (606 models, 1869 implants; n=20 studies); PICO 2: patients (801 patients, 1235 implants; n=17 studies); PICO 3: none; no cadaver studies
InterventionStatic computer-assisted implant surgery (sCAIS) and dynamic computer-assisted implant surgery (dCAIS)sCAIS; dCAIS (dCAIS plus sCAIS combinations in some studies)
ComparisonFreehand placement; sCAIS vs dCAISFreehand; sCAIS vs dCAIS
OutcomesTransfer accuracy: axial deviation (degrees), global coronal deviation (mm), global apical deviation (mm), mean with SDAxial, global coronal and global apical deviation (mean difference, random effects)
Study designsComparative studies (RCT, CCT, case-control, comparative cohort); in vitro, cadaver, animal and human studies; English or GermanIn vitro studies (n=20); 10 RCTs, 5 retrospective cohort studies and 2 retrospective case-control studies (n=17); no animal or cadaver studies
TimingNot specifiedNot specified

AMSTAR 2 items

Two independent extractors rated each item. Their ratings are shown side by side because they have not been reconciled yet. The overall rating follows Shea et al. 2017: one critical flaw gives Low, more than one gives Critically Low.

ItemExtractor AExtractor BAgree
1Research question includes PICO componentsYesYesyes
2Protocol established before the reviewcriticalPartial YesPartial Yesyes
3Choice of study designs explainedNoYesno
4Comprehensive literature searchcriticalPartial YesPartial Yesyes
5Study selection in duplicateYesYesyes
6Data extraction in duplicateYesYesyes
7List of excluded studies with reasonscriticalYesYesyes
8Included studies described in detailYesYesyes
9Risk of bias assessed satisfactorilycriticalRCT: Yes · NRSI: Partial YesNRSI: Partial Yes · RCT: Yesno
10Funding of included studies reportedYesYesyes
11Appropriate meta-analysis methodscriticalRCT: Yes · NRSI: NoNRSI: No · RCT: Yesno
12Impact of risk of bias on the pooled resultsNoNoyes
13Risk of bias accounted for in interpretationcriticalYesYesyes
14Heterogeneity explainedYesYesyes
15Publication bias investigatedcriticalYesYesyes
16Conflicts of interest reportedYesYesyes
OverallLowLowyes