Non-Cochrane · aetiology · PM41682835

The Relationship Between Malocclusion and Periodontal Health in Children and Adolescents: A Systematic Review and Meta-Analysis.

Szyszka-Sommerfeld Liliana, Machoy-Rakoczy Monika, Belova Alla, et al. · Journal of clinical medicine · 2026 · PubMed · doi:10.3390/jcm15031155

Findings

Population Children and adolescents (under 18 years)

2 findings

Malocclusion (malpositioned teeth such as crowding or lack of spacing; Angle Class II or III molar relationship)No malocclusionGingivitis assessed with the Gingival Bleeding Index (GBI)
Cross-sectional · Schools and clinics · Overall (Feldens 2006 and Sharma 2021)
OR 1.66 [1.27, 2.16]
Very low
Downgraded: risk of bias
2 studies
Malocclusion (malpositioned teeth such as crowding or lack of spacing; Angle Class II or III molar relationship)No malocclusionDental plaque accumulation (visual plaque and OHI-S, dichotomized)
Cross-sectional · Schools and clinics · Overall (Fernandez-Riveiro 2021 two age strata and Pineda 2020)
OR 2.33 [1.18, 4.60]
Very low
Downgraded: risk of bias, imprecision, inconsistency
2 studies

Included primary studies 19

Open in Studies
StudyYearAlso included byOutcomes it informs hereTrial data
Kolawole 2019
Association between malocclusion, caries and oral hygiene in children 6 to 12 years old resident in suburban Nigeria.
PMID:31775712
20192 other reviewsnot statednot extracted yet
Pineda 2020
Relationship between the Normative Need for Orthodontic Treatment and Oral Health in Mexican Adolescents Aged 13-15 Years Old.
PMID:33153121
20201 other reviewDental plaque accumulation (visual plaque and OHI-S, dichotomized)not extracted yet
Abu Alhaija 2006
Relationship between tooth irregularity and periodontal disease in children with regular dental visits.
PMID:16937854
2006this review onlynot statednot extracted yet
Addy 1988
The association between tooth irregularity and plaque accumulation, gingivitis, and caries in 11-12-year-old children.
PMID:3162883
1988this review onlynot statednot extracted yet
Ashley 1998
The relationship between irregularity of the incisor teeth, plaque, and gingivitis: a study in a group of schoolchildren aged 11-14 years.
PMID:9558766
1998this review onlynot statednot extracted yet
Buczkowska-Radlinska 2012
Anterior tooth crowding and prevalence of dental caries in children in Szczecin, Poland.
PMID:22779379
2012this review onlynot statednot extracted yet
Cortellazzi 2008
Risk indicators of gingivitis in 5-year-old Brazilian children.
PMID:18637390
2008this review onlynot statednot extracted yet
Feldens 2006
Distribution of plaque and gingivitis and associated factors in 3- to 5-year-old Brazilian children.
PMID:16734306
2006this review onlyGingivitis assessed with the Gingival Bleeding Index (GBI)not extracted yet
Fernandez-Riveiro 2021
The Dental Aesthetic Index and Its Association with Dental Caries, Dental Plaque and Socio-Demographic Variables in Schoolchildren Aged 12…
PMID:34574666
2021this review onlyDental plaque accumulation (visual plaque and OHI-S, dichotomized)not extracted yet
Gabris 2006
Prevalence of malocclusions in Hungarian adolescents.
PMID:16923783
2006this review onlynot statednot extracted yet
Goel 2018
The relationship of malocclusion with periodontal status, dental caries, and sociodemographic factors in school children of Ludhiana
DOI:10.4103/ijds.ijds_1_18
2018this review onlynot statednot extracted yet
Jafari 2024
Effect of malocclusion severity on oral health and its correlation with socioeconomical status in Iranian adolescents.
PMID:39465393
2024this review onlynot statednot extracted yet
Kukletova 2012
Relationship between gingivitis severity, caries experience and orthodontic anomalies in 13-15 year-old adolescents in Brno, Czech Republic.
PMID:22779381
2012this review onlynot statednot extracted yet
Medina-Vega 2024
Periodontal status among 12-year-old schoolchildren: a population-based cross-sectional study in Quito, Ecuador.
PMID:38198302
2024this review onlynot statednot extracted yet
Nalcaci 2012
The relationship of orthodontic treatment need with periodontal status, dental caries, and sociodemographic factors.
PMID:23193381
2012this review onlynot statednot extracted yet
Oz 2019
Evaluation of the Relationship Between Malocclusion and the Periodontal Health, Caries, Socio-economic Status of Children
DOI:10.4274/meandros.galenos.2018.63835
2019this review onlynot statednot extracted yet
Salim 2021
Relationship between dental caries, oral hygiene and malocclusion among Syrian refugee children and adolescents: a cross-sectional study.
PMID:34876100
2021this review onlynot statednot extracted yet
Sharma 2021
Prevalence of Gingivitis and Associated Factors in 619-Year-Old Children in Rudraprayag District, Uttarakhand
DOI:10.4103/jiaphd.jiaphd_80_21
2021this review onlyGingivitis assessed with the Gingival Bleeding Index (GBI)not extracted yet
Tariq 2024
Malocclusion: Prevalence and Determinants among Adolescents of Karachi, Pakistan.
PMID:37059446
2024this review onlynot statednot extracted yet

Overlap with other reviews

Reviews that include the same primary studies are not independent evidence. Shared counts match studies by PMID, DOI or NCT, and otherwise by author and year (a probable match). Only the non-Cochrane dental reviews have study lists, so overlap with Cochrane reviews is not counted yet.

Review question

ElementPlanned (methods)Found (results)
PopulationChildren and adolescents (under 18 years) with malocclusionChildren and adolescents aged 3 to 19 years (n=11954)
InterventionExposure: malocclusion of any type or severityMalocclusion: crowding, spacing, Angle class, DAI, IOTN, TPI (n=19)
ComparisonChildren and adolescents without malocclusionNo malocclusion (n=19)
OutcomesGingivitis (GI, GBI, BOP, GB; primary); dental plaque (API, OHI-S, PI, VPI) and CPITN/CPI (secondary)Gingivitis (n=10); dental plaque (n=10); CPITN/CPI (n=4)
Study designsObservational studiesCross-sectional studies (n=19)
TimingNot specifiedNot specified