Non-Cochrane · intervention · PM41590161

Comparative Wear of Opposing Natural Enamel by Different Ceramic Materials in Fixed Dental Protheses: A Systematic Review and Meta-Analysis.

Rosa Cleber Davi Del Rei Daltro, Bento Victor Augusto Alves, Duarte Nathália Dantas, et al. · Dentistry journal · 2026 · PubMed · doi:10.3390/dj14010037

Findings

12 findings

Population
Patients with single posterior ceramic crowns (natural opposing posterior enamel)Monolithic zirconia single-unit crown opposing natural enamelNatural enamel opposing natural toothVertical enamel wear (um) at 6 months
6 months · Clinical (patients with single posterior crowns) · 6 months
SMD -1.06 [-3.23, 1.12]
GRADE not reported
2 studies · 134 participants
Patients with single posterior ceramic crowns (natural opposing posterior enamel)Monolithic zirconia single-unit crown opposing natural enamelNatural enamel opposing natural toothVertical enamel wear (um), overall
6 to 24 months · Clinical (patients with single posterior crowns) · Overall
SMD -1.32 [-2.06, -0.57]
GRADE not reported
9 studies · 627 participants
Patients with single posterior ceramic crowns (natural opposing posterior enamel)Monolithic zirconia single-unit crown opposing natural enamelNatural enamel opposing natural toothVertical enamel wear (um) at 24 months
24 months · Clinical (patients with single posterior crowns) · 24 months
SMD 0.12 [-1.62, 1.86]
GRADE not reported
2 studies · 88 participants
Patients with single posterior ceramic crowns (natural opposing posterior enamel)Monolithic zirconia single-unit crown opposing natural enamelNatural enamel opposing natural toothVertical enamel wear (um) at 18 months
18 months · Clinical (patients with single posterior crowns) · 18 months
SMD -0.5 [-1.07, 0.08]
GRADE not reported
1 study · 48 participants
Patients with single posterior ceramic crowns (natural opposing posterior enamel)Monolithic zirconia single-unit crown opposing natural enamelNatural enamel opposing natural toothVertical enamel wear (um) at 12 months
12 months · Clinical (patients with single posterior crowns) · 12 months
SMD -1.88 [-2.93, -0.83]
GRADE not reported
8 studies · 357 participants
Patients with single posterior ceramic crowns (natural opposing posterior enamel)Monolithic lithium disilicate single-unit crown opposing natural enamelNatural enamel opposing natural toothVertical enamel wear (um) at 12 months
12 months · Clinical (patients with single posterior crowns) · 12 months
SMD -0.35 [-0.77, 0.06]
GRADE not reported
2 studies · 92 participants
Patients with single posterior ceramic crowns (natural opposing posterior enamel)Monolithic lithium disilicate single-unit crown opposing natural enamelNatural enamel opposing natural toothVertical enamel wear (um) at 18 months
18 months · Clinical (patients with single posterior crowns) · 18 months
SMD -0.61 [-1.19, -0.03]
GRADE not reported
1 study · 48 participants
Patients with single posterior ceramic crowns (natural opposing posterior enamel)Monolithic lithium disilicate single-unit crown opposing natural enamelNatural enamel opposing natural toothVertical enamel wear (um) at 24 months
24 months · Clinical (patients with single posterior crowns) · 24 months
SMD -0.25 [-0.82, 0.32]
GRADE not reported
1 study · 48 participants
Patients with single posterior ceramic crowns (natural opposing posterior enamel)Monolithic lithium disilicate single-unit crown opposing natural enamelNatural enamel opposing natural toothVertical enamel wear (um), overall
6 to 24 months · Clinical (patients with single posterior crowns) · Overall
SMD -0.45 [-0.71, -0.19]
GRADE not reported
2 studies · 236 participants
Patients with single posterior ceramic crowns (natural opposing posterior enamel)Monolithic lithium disilicate single-unit crown opposing natural enamelNatural enamel opposing natural toothVertical enamel wear (um) at 6 months
6 months · Clinical (patients with single posterior crowns) · 6 months
SMD -0.72 [-1.3, -0.13]
GRADE not reported
1 study · 48 participants
Patients with single posterior ceramic crowns (natural opposing posterior enamel)Metal-ceramic (feldspathic veneer) single-unit crown opposing natural enamelNatural enamel opposing natural toothVertical enamel wear (um), overall
12 months · Clinical (patients with single posterior crowns) · Overall
SMD -2.77 [-5.66, 0.13]
GRADE not reported
3 studies · 119 participants
Patients with single posterior crowns (zirconia vs metal-ceramic)Monolithic zirconia single-unit crownMetal-ceramic (feldspathic veneer) single-unit crownVertical enamel wear (um), zirconia vs metal-ceramic
12 months · Clinical (patients with single posterior crowns) · Overall
SMD -0.19 [-2.32, 1.93]
GRADE not reported
3 studies · 110 participants

Included primary studies 9

Open in Studies
StudyYearAlso included byOutcomes it informs hereTrial data
Deval 2021
A Clinical Comparative Evaluation Of The Wear Of Enamel Antagonist To Monolithic Zirconia And Metal-Ceramic Crowns.
PMID:33750998
2021this review onlyVertical enamel wear (um), overall; Vertical enamel wear (um), zirconia vs metal-ceramicnot extracted yet
Esquivel-Upshaw 2020
Novel methodology for measuring intraoral wear in enamel and dental restorative materials.
PMID:32955159
2020this review onlyVertical enamel wear (um), overall; Vertical enamel wear (um), zirconia vs metal-ceramicnot extracted yet
Mundhe 2015
Clinical study to evaluate the wear of natural enamel antagonist to zirconia and metal ceramic crowns.
PMID:25985742
2015this review onlyVertical enamel wear (um), overall; Vertical enamel wear (um), zirconia vs metal-ceramicnot extracted yet
Nazirkar 2020
Comparative evaluation of natural enamel wear against polished yitrium tetragonal zirconia and polished lithium disilicate - An in vivo…
PMID:32089603
2020this review onlyVertical enamel wear (um), overallnot extracted yet
Selvaraj 2021
Evaluation of the wear of glazed and polished zirconia crowns and the opposing natural teeth: A clinical pilot study.
PMID:32665120
2021this review onlyVertical enamel wear (um), overallnot extracted yet
Stober 2016
Clinical assessment of enamel wear caused by monolithic zirconia crowns.
PMID:27198539
2016this review onlyVertical enamel wear (um), overallnot extracted yet
Tang 2021
Quantitative analysis on the wear of monolithic zirconia crowns on antagonist teeth.
PMID:33663477
2021this review onlyVertical enamel wear (um), overallnot extracted yet
Woraganjanaboon & Anunmana 2024
3D quantitative analysis and SEM qualitative analysis of natural antagonist enamel opposing CAD-CAM monolithic zirconia or lithium…
PMID:38455676
2024this review onlyVertical enamel wear (um), overallnot extracted yet
Woraganjanaboon 2025
A two-year clinical trial of enamel wear opposing 5Y-TZP and lithium disilicate crowns.
PMID:39138093
2025this review onlyVertical enamel wear (um), overallnot extracted yet

Review question

ElementPlanned (methods)Found (results)
PopulationPatients with single-unit posterior ceramic crowns; at least 10 participants203 patients (n=203), age 18 to 73 years
InterventionSingle-unit ceramic crowns (zirconia, lithium disilicate, feldspathic metal-ceramic)Monolithic zirconia (n=9 studies); monolithic lithium disilicate (n=2); metal-ceramic with feldspathic veneer (n=3)
ComparisonNatural antagonist posterior tooth (enamel-to-enamel contact)Natural enamel antagonist
OutcomesQuantitative antagonist enamel wear (micrometers)Vertical wear of opposing enamel (micrometers), SMD
Study designsRCTs or prospective studies (non-RCTs); in vitro studies, case reports and studies without follow-up excluded9 studies: 5 RCTs and 4 prospective studies
TimingLong-term follow-up (not otherwise specified)6, 12, 18 and 24 months