Impact of dental caries on the quality of life of adolescents: A systematic review and meta-analysis.
Botelho-Filho Carlos Roberto, Bordin Giuliana Martina, Paula Isabela Cristina Santos Freire de, et al. · Revista brasileira de epidemiologia = Brazilian journal of epidemiology · 2025 · PubMed · doi:10.1590/1980-549720250018
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Review question
| Element | Planned (methods) | Found (results) |
|---|---|---|
| Population | Adolescents aged 10 to 19 years (WHO age range) | Adolescents aged 5 to 19 years (mean 14.4 years) (n=20 studies) |
| Intervention | Presence of dental caries (exposure) | Dental caries: DMFT in 15 studies, untreated caries in 4, CAST in 1 (n=20) |
| Comparison | Absence of dental caries (control) | Adolescents without dental caries |
| Outcomes | Impact of oral health on daily performance, measured by OIDP or Child-OIDP | Negative oral-health impact on daily performance; OIDP in 8 studies, Child-OIDP in 11, both in 1 (n=20) |
| Study designs | Observational studies assessing oral clinical conditions by physical examination | All 20 included studies cross-sectional; 17 school-based, 1 household, 2 secondary data (n=20) |
| Timing | Not specified (no publication-date restriction) | Not specified |
Search date: January 2022; updated March 2024 (studies up until March 2024). Databases: MEDLINE via PubMed; Scopus; Web of Science; LILACS/BBO via the Virtual Health Library; grey literature (Google Scholar first 100 hits, OpenGrey, ProQuest Dissertations and Theses); reference lists hand-searched
Questions and results
Dental caries (presence or experience) vs Adolescents without dental caries
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Negative oral-health impact on daily performance (OIDP or Child-OIDP) Cross-sectional (concurrent exposure and outcome); oral impacts recalled over the prior 6 months · Overall (all meta-analyzed studies pooled; both instruments and both caries definitions) Dental caries is associated with a worse oral-health impact on adolescents' daily performance: pooled PR 1.52 (95% CI 1.15 to 2.01) from 9 cross-sectional studies with very high heterogeneity (I2=97%); the body of evidence was not GRADE-rated (ungraded). Source: Results (meta-analysis paragraph); Supplementary Material 2; Abstract · same question in other reviews | PR 1.52 [1.15, 2.01] | 9 studies | Ungraded |
Dental caries (presence or experience) vs Adolescents without dental caries
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Negative oral-health impact on daily performance measured by Child-OIDP Cross-sectional (concurrent exposure and outcome); oral impacts recalled over the prior 6 months · Instrument subgroup: Child-OIDP In the Child-OIDP subgroup, dental caries is associated with a worse oral-health impact: PR 1.66 (95% CI 1.19 to 2.31) from 6 studies (I2=96%); ungraded, and not statistically different from the OIDP subgroup (p=0.96). Source: Results (subgroup by instrument); Supplementary Material 4; Abstract · same question in other reviews | PR 1.66 [1.19, 2.31] | 6 studies | Ungraded |
Dental caries (presence or experience) vs Adolescents without dental caries
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Negative oral-health impact on daily performance measured by OIDP Cross-sectional (concurrent exposure and outcome); oral impacts recalled over the prior 6 months · Instrument subgroup: OIDP (all 3 studies) In the OIDP subgroup, the association of dental caries with oral-health impact was not statistically significant: PR 1.68 (95% CI 0.89 to 3.17) from 3 studies (I2=94%); ungraded. Source: Results (subgroup by instrument); Supplementary Material 4 · same question in other reviews | PR 1.68 [0.89, 3.17] | 3 studies | Ungraded |
Negative oral-health impact on daily performance measured by OIDP Cross-sectional (concurrent exposure and outcome); oral impacts recalled over the prior 6 months · Instrument subgroup: OIDP, sensitivity analysis excluding Krisdapong et al. When Krisdapong et al. was removed from the OIDP subgroup, heterogeneity disappeared (I2=0%) and the association became significant: PR 1.21 (95% CI 1.15 to 1.28) from 2 studies; ungraded sensitivity analysis. Source: Results (additional sensitivity analysis); Supplementary Material 5 · same question in other reviews | PR 1.21 [1.15, 1.28] | 2 studies | Ungraded |
Presence of dental caries vs Adolescents without dental caries
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Negative oral-health impact on daily performance (OIDP or Child-OIDP) Cross-sectional (concurrent exposure and outcome); oral impacts recalled over the prior 6 months · Caries-definition subgroup: presence of dental caries For presence of dental caries, the pooled association with oral-health impact was not statistically significant: PR 1.19 (95% CI 0.77 to 1.84) from 3 studies (I2=96%); ungraded. Source: Results (subgroup by caries definition); Supplementary Material 6 · same question in other reviews | PR 1.19 [0.77, 1.84] | 3 studies | Ungraded |
Experience of dental caries (caries history, e.g. DMFT) vs Adolescents without dental caries
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Negative oral-health impact on daily performance (OIDP or Child-OIDP) Cross-sectional (concurrent exposure and outcome); oral impacts recalled over the prior 6 months · Caries-definition subgroup: experience of dental caries For experience (history) of dental caries, adolescents had a significantly worse oral-health impact: PR 1.72 (95% CI 1.23 to 2.43) from 6 studies (I2=97%); ungraded, and not statistically different from the presence subgroup (p=0.19). Source: Results (subgroup by caries definition); Supplementary Material 6; Abstract · same question in other reviews | PR 1.72 [1.23, 2.43] | 6 studies | Ungraded |
Included primary studies 22
Open as a trial list| Study | Also included by | Outcomes it informs here | Trial PICO | Results |
|---|---|---|---|---|
| Mohamed et al. 2019 Oral clinical status and oral health-related quality of life: is socioeconomic position a mediator or a moderator? PMID:30152041 | 1 other review | not stated | not extracted yet | not extracted yet |
| Alzahrani et al. 2019 Association between oral diseases and impact on daily performance among male Saudi schoolchildren. PMID:31890302 | this review only | Negative oral-health impact on daily performance (OIDP or Child-OIDP) | not extracted yet | not extracted yet |
| Amilani et al. 2021 Key factors associated with oral health-related quality of life in Sri Lankan adolescents: a cross sectional study. PMID:33926434 | this review only | not stated | not extracted yet | not extracted yet |
| Anthony et al. 2023 Assessing association of dental caries with child oral impact on daily performance; a cross-sectional study of adolescents in Copperbelt… PMID:37198633 | this review only | Negative oral-health impact on daily performance (OIDP or Child-OIDP) | not extracted yet | not extracted yet |
| Bakhtiar et al. (2014) matched by author and year (probable) | this review only | not stated | not extracted yet | not extracted yet |
| Bakhtiar et al. 2014 Retinol-binding protein 4: a novel adipokine implicated in the genesis of LGA in the absence of gestational diabetes mellitus. PMID:20146659 | this review only | not stated | not extracted yet | not extracted yet |
| da Cunha et al. 2017 Social vulnerability and factors associated with oral impact on daily performance among adolescents. PMID:28854934 | this review only | Negative oral-health impact on daily performance (OIDP or Child-OIDP) | not extracted yet | not extracted yet |
| Gajic et al. 2018 Oral health-related quality of life among Belgrade adolescents DOI:10.2298/vsp151027318g | this review only | not stated | not extracted yet | not extracted yet |
| Gushi et al. 2020 Fatores associados ao impacto das condições de saúde bucal nas atividades de vida diária de adolescentes, Estado de São Paulo, 2015 DOI:10.1590/1980-549720200098 | this review only | not stated | not extracted yet | not extracted yet |
| Karki et al. 2019 Influence of dental caries on oral health‐related quality of life, school absenteeism and school performance among Nepalese schoolchildren DOI:10.1111/cdoe.12485 | this review only | not stated | not extracted yet | not extracted yet |
| Kozmhinsky et al. 2016 Sociodemographic Factors and Oral Health Conditions Related to the Impact on the Quality of Life of Adolescents DOI:10.4034/pboci.2016.161.04 | this review only | Negative oral-health impact on daily performance (OIDP or Child-OIDP) | not extracted yet | not extracted yet |
| Krisdapong et al. (2012, 2013) PMID:20122013 | this review only | not stated | not extracted yet | not extracted yet |
| Krisdapong et al. 2012/2013 Impacts on Quality of Life Related to Dental Caries in a National Representative Sample of Thai 12- and 15-Year-Olds DOI:10.1159/000342893 | this review only | Negative oral-health impact on daily performance (OIDP or Child-OIDP) | not extracted yet | not extracted yet |
| Kumar et al. 2015 Oral health impact, dental caries experience, and associated factors in 12–15-year-old school children in India DOI:10.1515/ijamh-2015-0041 | this review only | Negative oral-health impact on daily performance (OIDP or Child-OIDP) | not extracted yet | not extracted yet |
| Leao et al. 2015 Oral health and quality of life: an epidemiological survey of adolescents from settlement in Pontal do Paranapanema/SP, Brazil DOI:10.1590/1413-812320152011.00632015 | this review only | not stated | not extracted yet | not extracted yet |
| Martins et al. 2016 Impact of Dental Caries onQuality of Life of School Children DOI:10.4034/pboci.2016.161.32 | this review only | not stated | not extracted yet | not extracted yet |
| Mashoto et al. 2009 Changes in quality of life among Norwegian school children: a six-month follow-up study. PMID:19193211 | this review only | not stated | not extracted yet | not extracted yet |
| Mtaya et al. 2007 Applicability of an abbreviated version of the Child-OIDP inventory among primary schoolchildren in Tanzania. PMID:17631038 | this review only | Negative oral-health impact on daily performance (OIDP or Child-OIDP) | not extracted yet | not extracted yet |
| Naidoo et al. 2013 matched by author and year (probable) | this review only | not stated | not extracted yet | not extracted yet |
| Simangwa et al. 2020 Oral impacts on daily performances and its socio-demographic and clinical distribution: a cross-sectional study of adolescents living in… PMID:32532339 | this review only | Negative oral-health impact on daily performance (OIDP or Child-OIDP) | not extracted yet | not extracted yet |
| Vazquez et al. 2015 Quality of life and socio-dental impact among underprivileged Brazilian adolescents DOI:10.1007/s11136-014-0795-4 | this review only | not stated | not extracted yet | not extracted yet |
| Wu et al. 2021 DOI:10.3290/j.cjdr.b1530497 | this review only | Negative oral-health impact on daily performance (OIDP or Child-OIDP) | not extracted yet | not extracted yet |
Overlap with other reviews
Reviews that include the same primary studies are not independent evidence. Shared counts match studies by PMID, DOI or NCT, and otherwise by author and year (a probable match).
| Review | Shared studies | Jaccard |
|---|---|---|
| Malocclusions and quality of life among adolescents: a systematic review and meta-analysis. (2023) | 1 | 0.03 |