Non-Cochrane · aetiology · PM40332172

Impact of dental caries on the quality of life of adolescents: A systematic review and meta-analysis.

Botelho-Filho Carlos Roberto, Bordin Giuliana Martina, Paula Isabela Cristina Santos Freire de, et al. · Revista brasileira de epidemiologia = Brazilian journal of epidemiology · 2025 · PubMed · doi:10.1590/1980-549720250018

Oral HealthDental cariesAMSTAR 2: not applicable
Full textEvery question was extracted from the full text, figures and supplements by two independent LLM extractors, disagreements adjudicated. Rows cite where in the review the value comes from.
Questions
6
current version
GRADE rated
0
No studies
0
Included studies
22
linked below
No studies 0 · 0%Ungraded 6 · 100%Very low 0 · 0%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Review question

ElementPlanned (methods)Found (results)
PopulationAdolescents aged 10 to 19 years (WHO age range)Adolescents aged 5 to 19 years (mean 14.4 years) (n=20 studies)
InterventionPresence of dental caries (exposure)Dental caries: DMFT in 15 studies, untreated caries in 4, CAST in 1 (n=20)
ComparisonAbsence of dental caries (control)Adolescents without dental caries
OutcomesImpact of oral health on daily performance, measured by OIDP or Child-OIDPNegative oral-health impact on daily performance; OIDP in 8 studies, Child-OIDP in 11, both in 1 (n=20)
Study designsObservational studies assessing oral clinical conditions by physical examinationAll 20 included studies cross-sectional; 17 school-based, 1 household, 2 secondary data (n=20)
TimingNot specified (no publication-date restriction)Not specified

Search date: January 2022; updated March 2024 (studies up until March 2024). Databases: MEDLINE via PubMed; Scopus; Web of Science; LILACS/BBO via the Virtual Health Library; grey literature (Google Scholar first 100 hits, OpenGrey, ProQuest Dissertations and Theses); reference lists hand-searched

Questions and results

Dental caries (presence or experience) vs Adolescents without dental caries

Population: Adolescents aged 10 to 19 years
1 question
OutcomeEffectEvidenceStatus / GRADE
Negative oral-health impact on daily performance (OIDP or Child-OIDP)
Cross-sectional (concurrent exposure and outcome); oral impacts recalled over the prior 6 months · Overall (all meta-analyzed studies pooled; both instruments and both caries definitions)
Dental caries is associated with a worse oral-health impact on adolescents' daily performance: pooled PR 1.52 (95% CI 1.15 to 2.01) from 9 cross-sectional studies with very high heterogeneity (I2=97%); the body of evidence was not GRADE-rated (ungraded).
Source: Results (meta-analysis paragraph); Supplementary Material 2; Abstract · same question in other reviews
PR 1.52 [1.15, 2.01]9 studiesUngraded

Dental caries (presence or experience) vs Adolescents without dental caries

Population: Adolescents aged 10 to 19 years
1 question
OutcomeEffectEvidenceStatus / GRADE
Negative oral-health impact on daily performance measured by Child-OIDP
Cross-sectional (concurrent exposure and outcome); oral impacts recalled over the prior 6 months · Instrument subgroup: Child-OIDP
In the Child-OIDP subgroup, dental caries is associated with a worse oral-health impact: PR 1.66 (95% CI 1.19 to 2.31) from 6 studies (I2=96%); ungraded, and not statistically different from the OIDP subgroup (p=0.96).
Source: Results (subgroup by instrument); Supplementary Material 4; Abstract · same question in other reviews
PR 1.66 [1.19, 2.31]6 studiesUngraded

Dental caries (presence or experience) vs Adolescents without dental caries

Population: Adolescents aged 10 to 19 years
2 questions
OutcomeEffectEvidenceStatus / GRADE
Negative oral-health impact on daily performance measured by OIDP
Cross-sectional (concurrent exposure and outcome); oral impacts recalled over the prior 6 months · Instrument subgroup: OIDP (all 3 studies)
In the OIDP subgroup, the association of dental caries with oral-health impact was not statistically significant: PR 1.68 (95% CI 0.89 to 3.17) from 3 studies (I2=94%); ungraded.
Source: Results (subgroup by instrument); Supplementary Material 4 · same question in other reviews
PR 1.68 [0.89, 3.17]3 studiesUngraded
Negative oral-health impact on daily performance measured by OIDP
Cross-sectional (concurrent exposure and outcome); oral impacts recalled over the prior 6 months · Instrument subgroup: OIDP, sensitivity analysis excluding Krisdapong et al.
When Krisdapong et al. was removed from the OIDP subgroup, heterogeneity disappeared (I2=0%) and the association became significant: PR 1.21 (95% CI 1.15 to 1.28) from 2 studies; ungraded sensitivity analysis.
Source: Results (additional sensitivity analysis); Supplementary Material 5 · same question in other reviews
PR 1.21 [1.15, 1.28]2 studiesUngraded

Presence of dental caries vs Adolescents without dental caries

Population: Adolescents aged 10 to 19 years
1 question
OutcomeEffectEvidenceStatus / GRADE
Negative oral-health impact on daily performance (OIDP or Child-OIDP)
Cross-sectional (concurrent exposure and outcome); oral impacts recalled over the prior 6 months · Caries-definition subgroup: presence of dental caries
For presence of dental caries, the pooled association with oral-health impact was not statistically significant: PR 1.19 (95% CI 0.77 to 1.84) from 3 studies (I2=96%); ungraded.
Source: Results (subgroup by caries definition); Supplementary Material 6 · same question in other reviews
PR 1.19 [0.77, 1.84]3 studiesUngraded

Experience of dental caries (caries history, e.g. DMFT) vs Adolescents without dental caries

Population: Adolescents aged 10 to 19 years
1 question
OutcomeEffectEvidenceStatus / GRADE
Negative oral-health impact on daily performance (OIDP or Child-OIDP)
Cross-sectional (concurrent exposure and outcome); oral impacts recalled over the prior 6 months · Caries-definition subgroup: experience of dental caries
For experience (history) of dental caries, adolescents had a significantly worse oral-health impact: PR 1.72 (95% CI 1.23 to 2.43) from 6 studies (I2=97%); ungraded, and not statistically different from the presence subgroup (p=0.19).
Source: Results (subgroup by caries definition); Supplementary Material 6; Abstract · same question in other reviews
PR 1.72 [1.23, 2.43]6 studiesUngraded

Included primary studies 22

Open as a trial list
StudyAlso included byOutcomes it informs hereTrial PICOResults
Mohamed et al. 2019
Oral clinical status and oral health-related quality of life: is socioeconomic position a mediator or a moderator?
PMID:30152041
1 other reviewnot statednot extracted yetnot extracted yet
Alzahrani et al. 2019
Association between oral diseases and impact on daily performance among male Saudi schoolchildren.
PMID:31890302
this review onlyNegative oral-health impact on daily performance (OIDP or Child-OIDP)not extracted yetnot extracted yet
Amilani et al. 2021
Key factors associated with oral health-related quality of life in Sri Lankan adolescents: a cross sectional study.
PMID:33926434
this review onlynot statednot extracted yetnot extracted yet
Anthony et al. 2023
Assessing association of dental caries with child oral impact on daily performance; a cross-sectional study of adolescents in Copperbelt…
PMID:37198633
this review onlyNegative oral-health impact on daily performance (OIDP or Child-OIDP)not extracted yetnot extracted yet
Bakhtiar et al. (2014)
matched by author and year (probable)
this review onlynot statednot extracted yetnot extracted yet
Bakhtiar et al. 2014
Retinol-binding protein 4: a novel adipokine implicated in the genesis of LGA in the absence of gestational diabetes mellitus.
PMID:20146659
this review onlynot statednot extracted yetnot extracted yet
da Cunha et al. 2017
Social vulnerability and factors associated with oral impact on daily performance among adolescents.
PMID:28854934
this review onlyNegative oral-health impact on daily performance (OIDP or Child-OIDP)not extracted yetnot extracted yet
Gajic et al. 2018
Oral health-related quality of life among Belgrade adolescents
DOI:10.2298/vsp151027318g
this review onlynot statednot extracted yetnot extracted yet
Gushi et al. 2020
Fatores associados ao impacto das condições de saúde bucal nas atividades de vida diária de adolescentes, Estado de São Paulo, 2015
DOI:10.1590/1980-549720200098
this review onlynot statednot extracted yetnot extracted yet
Karki et al. 2019
Influence of dental caries on oral health‐related quality of life, school absenteeism and school performance among Nepalese schoolchildren
DOI:10.1111/cdoe.12485
this review onlynot statednot extracted yetnot extracted yet
Kozmhinsky et al. 2016
Sociodemographic Factors and Oral Health Conditions Related to the Impact on the Quality of Life of Adolescents
DOI:10.4034/pboci.2016.161.04
this review onlyNegative oral-health impact on daily performance (OIDP or Child-OIDP)not extracted yetnot extracted yet
Krisdapong et al. (2012, 2013)
PMID:20122013
this review onlynot statednot extracted yetnot extracted yet
Krisdapong et al. 2012/2013
Impacts on Quality of Life Related to Dental Caries in a National Representative Sample of Thai 12- and 15-Year-Olds
DOI:10.1159/000342893
this review onlyNegative oral-health impact on daily performance (OIDP or Child-OIDP)not extracted yetnot extracted yet
Kumar et al. 2015
Oral health impact, dental caries experience, and associated factors in 12–15-year-old school children in India
DOI:10.1515/ijamh-2015-0041
this review onlyNegative oral-health impact on daily performance (OIDP or Child-OIDP)not extracted yetnot extracted yet
Leao et al. 2015
Oral health and quality of life: an epidemiological survey of adolescents from settlement in Pontal do Paranapanema/SP, Brazil
DOI:10.1590/1413-812320152011.00632015
this review onlynot statednot extracted yetnot extracted yet
Martins et al. 2016
Impact of Dental Caries onQuality of Life of School Children
DOI:10.4034/pboci.2016.161.32
this review onlynot statednot extracted yetnot extracted yet
Mashoto et al. 2009
Changes in quality of life among Norwegian school children: a six-month follow-up study.
PMID:19193211
this review onlynot statednot extracted yetnot extracted yet
Mtaya et al. 2007
Applicability of an abbreviated version of the Child-OIDP inventory among primary schoolchildren in Tanzania.
PMID:17631038
this review onlyNegative oral-health impact on daily performance (OIDP or Child-OIDP)not extracted yetnot extracted yet
Naidoo et al. 2013
matched by author and year (probable)
this review onlynot statednot extracted yetnot extracted yet
Simangwa et al. 2020
Oral impacts on daily performances and its socio-demographic and clinical distribution: a cross-sectional study of adolescents living in…
PMID:32532339
this review onlyNegative oral-health impact on daily performance (OIDP or Child-OIDP)not extracted yetnot extracted yet
Vazquez et al. 2015
Quality of life and socio-dental impact among underprivileged Brazilian adolescents
DOI:10.1007/s11136-014-0795-4
this review onlynot statednot extracted yetnot extracted yet
Wu et al. 2021
DOI:10.3290/j.cjdr.b1530497
this review onlyNegative oral-health impact on daily performance (OIDP or Child-OIDP)not extracted yetnot extracted yet

Overlap with other reviews

Reviews that include the same primary studies are not independent evidence. Shared counts match studies by PMID, DOI or NCT, and otherwise by author and year (a probable match).