Non-Cochrane · prognostic · PM40304173

Outcomes of root canal treatment performed by undergraduate students: A systematic review and meta-analysis.

Chien Philip Y-H, Hosseinpour Sepanta, Peters Ove A, et al. · International endodontic journal · 2026 · PubMed · doi:10.1111/iej.14246

Findings

19 findings

Population
Patients with permanent teeth treated by undergraduate dental studentsPrimary nonsurgical root canal treatment or retreatment by undergraduate studentsNone (success versus failure counts; no comparator)Clinical and radiographic treatment success
6 months to 8 years follow-up · University dental school student clinics · Overall
RD 0.43 [0.40, 0.46]
GRADE not reported
11 studies · 2065 participants
Roots of permanent teeth treated by undergraduate dental studentsPreoperative vital pulp diagnosisPreoperative necrotic pulpClinical and radiographic treatment success rate (per root)
6 months to 8 years follow-up · University dental school student clinics · Vital pulp
Weighted pooled success rate (%) 87.8
GRADE not reported
3 studies · 329 participants
Roots of permanent teeth treated by undergraduate dental studentsPreoperative vital pulp diagnosisPreoperative necrotic pulpClinical and radiographic treatment success rate (per root)
6 months to 8 years follow-up · University dental school student clinics · Necrotic pulp
Unweighted pooled success rate (%) 62.2
GRADE not reported
3 studies · 442 participants
Roots of permanent teeth treated by undergraduate dental studentsPreoperative vital pulp diagnosisPreoperative necrotic pulpClinical and radiographic treatment success rate (per root)
6 months to 8 years follow-up · University dental school student clinics · Necrotic pulp
Weighted pooled success rate (%) 65.6
GRADE not reported
3 studies · 442 participants
Roots of permanent teeth treated by undergraduate dental studentsPreoperative vital pulp diagnosisPreoperative necrotic pulpClinical and radiographic treatment success rate (per root)
6 months to 8 years follow-up · University dental school student clinics · Vital pulp
Unweighted pooled success rate (%) 87.1
GRADE not reported
3 studies · 329 participants
Roots of permanent teeth treated by undergraduate dental studentsAbsence of preoperative periapical lesionPresence of preoperative periapical lesionClinical and radiographic treatment success rate (per root)
6 months to 8 years follow-up · University dental school student clinics · No preoperative periapical lesion
Weighted pooled success rate (%) 86.8
GRADE not reported
3 studies · 477 participants
Roots of permanent teeth treated by undergraduate dental studentsAbsence of preoperative periapical lesionPresence of preoperative periapical lesionClinical and radiographic treatment success rate (per root)
6 months to 8 years follow-up · University dental school student clinics · Preoperative periapical lesion present
Weighted pooled success rate (%) 56.3
GRADE not reported
3 studies · 294 participants
Roots of permanent teeth treated by undergraduate dental studentsAbsence of preoperative periapical lesionPresence of preoperative periapical lesionClinical and radiographic treatment success rate (per root)
6 months to 8 years follow-up · University dental school student clinics · Preoperative periapical lesion present
Unweighted pooled success rate (%) 55.8
GRADE not reported
3 studies · 294 participants
Roots of permanent teeth treated by undergraduate dental studentsAbsence of preoperative periapical lesionPresence of preoperative periapical lesionClinical and radiographic treatment success rate (per root)
6 months to 8 years follow-up · University dental school student clinics · No preoperative periapical lesion
Unweighted pooled success rate (%) 87.1
GRADE not reported
3 studies · 477 participants
Roots of permanent teeth treated by undergraduate dental studentsAnterior teethMolars (premolars also reported)Clinical and radiographic treatment success rate (per root)
6 months to 8 years follow-up · University dental school student clinics · Premolars
Unweighted pooled success rate (%) 79.4
GRADE not reported
3 studies · 216 participants
Roots of permanent teeth treated by undergraduate dental studentsAnterior teethMolars (premolars also reported)Clinical and radiographic treatment success rate (per root)
6 months to 8 years follow-up · University dental school student clinics · Anterior teeth
Weighted pooled success rate (%) 82.2
GRADE not reported
3 studies · 202 participants
Roots of permanent teeth treated by undergraduate dental studentsAnterior teethMolars (premolars also reported)Clinical and radiographic treatment success rate (per root)
6 months to 8 years follow-up · University dental school student clinics · Anterior teeth
Unweighted pooled success rate (%) 82.2
GRADE not reported
3 studies · 202 participants
Roots of permanent teeth treated by undergraduate dental studentsAnterior teethMolars (premolars also reported)Clinical and radiographic treatment success rate (per root)
6 months to 8 years follow-up · University dental school student clinics · Molars
Weighted pooled success rate (%) 68.7
GRADE not reported
3 studies · 351 participants
Roots of permanent teeth treated by undergraduate dental studentsAnterior teethMolars (premolars also reported)Clinical and radiographic treatment success rate (per root)
6 months to 8 years follow-up · University dental school student clinics · Molars
Unweighted pooled success rate (%) 68.7
GRADE not reported
3 studies · 351 participants
Roots of permanent teeth treated by undergraduate dental studentsAnterior teethMolars (premolars also reported)Clinical and radiographic treatment success rate (per root)
6 months to 8 years follow-up · University dental school student clinics · Premolars
Weighted pooled success rate (%) 79.4
GRADE not reported
3 studies · 216 participants
Roots of permanent teeth treated by undergraduate dental studentsMaxillary teethMandibular teethClinical and radiographic treatment success rate (per root)
6 months to 8 years follow-up · University dental school student clinics · Maxillary teeth
Unweighted pooled success rate (%) 76.8
GRADE not reported
3 studies · 436 participants
Roots of permanent teeth treated by undergraduate dental studentsMaxillary teethMandibular teethClinical and radiographic treatment success rate (per root)
6 months to 8 years follow-up · University dental school student clinics · Mandibular teeth
Unweighted pooled success rate (%) 72.1
GRADE not reported
3 studies · 335 participants
Roots of permanent teeth treated by undergraduate dental studentsMaxillary teethMandibular teethClinical and radiographic treatment success rate (per root)
6 months to 8 years follow-up · University dental school student clinics · Mandibular teeth
Weighted pooled success rate (%) 73.1
GRADE not reported
3 studies · 335 participants
Roots of permanent teeth treated by undergraduate dental studentsMaxillary teethMandibular teethClinical and radiographic treatment success rate (per root)
6 months to 8 years follow-up · University dental school student clinics · Maxillary teeth
Weighted pooled success rate (%) 76.8
GRADE not reported
3 studies · 436 participants

Included primary studies 11

Open in Studies
StudyYearAlso included byOutcomes it informs hereTrial data
Cunha 2020
Effect of Endodontic Sealer in Young Molars Treated by Undergraduate Students - A Randomized Clinical Trial.
PMID:33237229
20201 other reviewClinical and radiographic treatment successnot extracted yet
Azim 2016
The Tennessee study: factors affecting treatment outcome and healing time following nonsurgical root canal treatment.
PMID:25582870
2016this review onlyClinical and radiographic treatment success; Clinical and radiographic treatment success rate (per root)not extracted yet
Chaisophin 2022
matched by author and year (probable)
NRthis review onlyClinical and radiographic treatment successnot extracted yet
da Rocha 2022
Outcome of endodontic treatments performed by Brazilian undergraduate students: 3- to 8-year follow up.
PMID:36090508
2022this review onlyClinical and radiographic treatment successnot extracted yet
Daud 2021
matched by author and year (probable)
NRthis review onlyClinical and radiographic treatment successnot extracted yet
De Quadros 2005
Evaluation of endodontic treatments performed by students in a Brazilian Dental School.
PMID:16204682
2005this review onlyClinical and radiographic treatment successnot extracted yet
Mohammad 2023
matched by author and year (probable)
NRthis review onlyClinical and radiographic treatment successnot extracted yet
Pettiette 2001
Evaluation of success rate of endodontic treatment performed by students with stainless-steel K-files and nickel-titanium hand files.
PMID:11491636
2001this review onlyClinical and radiographic treatment successnot extracted yet
Polyzos 2018a
Factors Affecting the Outcome of Non-Surgical Endodontic Treatments Performed by Undergraduate Students in a Greek Dental School.
PMID:32161863
2018this review onlyClinical and radiographic treatment success; Clinical and radiographic treatment success rate (per root)not extracted yet
Polyzos 2018b
Quality of Root Canal Fillings Performed by Undergraduate Students and the Related Factors on the Treatment Outcome: A 2- to 5-Year…
PMID:32161875
2018this review onlyClinical and radiographic treatment success; Clinical and radiographic treatment success rate (per root)not extracted yet
Wen 2024
Evaluation of quality of root canal therapy performed by predoctoral students on endodontic outcome and quality of life of patients.
PMID:38853582
2024this review onlyClinical and radiographic treatment successnot extracted yet

Overlap with other reviews

Reviews that include the same primary studies are not independent evidence. Shared counts match studies by PMID, DOI or NCT, and otherwise by author and year (a probable match). Only the non-Cochrane dental reviews have study lists, so overlap with Cochrane reviews is not counted yet.

Review question

ElementPlanned (methods)Found (results)
PopulationPatients of all ages and health groups with permanent teeth treated by undergraduate or pre-doctoral studentsPermanent teeth (60 to 579 teeth per study; 771 roots in the pooled factor analyses; n=3 studies)
InterventionPrimary nonsurgical root canal treatment or nonsurgical retreatment performed by undergraduate studentsNonsurgical root canal treatment by undergraduate students (n=11 studies)
ComparisonN/ANone (success versus failure within studies)
OutcomesClinician-reported radiographic and clinical treatment outcomes (success); patient-reported outcomes and technical quality only studies excludedClinical and radiographic success (pooled risk difference, n=11; weighted and unweighted pooled success rates, n=3)
Study designsRCTs, retrospective, prospective, cross-sectional and cohort studies; English only; published 2000 onward10 retrospective observational studies and 1 RCT (n=11)
TimingNot specifiedRecall 6 months to 8 years

AMSTAR 2 items

Two independent extractors rated each item. Their ratings are shown side by side because they have not been reconciled yet. The overall rating follows Shea et al. 2017: one critical flaw gives Low, more than one gives Critically Low.

ItemExtractor AExtractor BAgree
1Research question includes PICO componentsNRYesno
2Protocol established before the reviewcriticalNRPartial Yesno
3Choice of study designs explainedNRNono
4Comprehensive literature searchcriticalNRPartial Yesno
5Study selection in duplicateNRYesno
6Data extraction in duplicateNRNono
7List of excluded studies with reasonscriticalNRNono
8Included studies described in detailNRYesno
9Risk of bias assessed satisfactorilycriticalNRRCT: Yes · NRSI: Partial Yesno
10Funding of included studies reportedNRNono
11Appropriate meta-analysis methodscriticalNRRCT: N/A · NRSI: Nono
12Impact of risk of bias on the pooled resultsNRNono
13Risk of bias accounted for in interpretationcriticalNRNono
14Heterogeneity explainedNRYesno
15Publication bias investigatedcriticalNRNono
16Conflicts of interest reportedNRYesno
OverallNRCritically Lowno