Cochrane · systematic review · CD011537

Intrauterine administration of human chorionic gonadotropin (hCG) for subfertile women undergoing assisted reproduction

Craciunas, L, Tsampras, N, Raine‐Fenning, N, et al. · Cochrane Database of Systematic Reviews · 2018 · Cochrane Library

Gynaecology and Fertility2 versionsAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
4
current version
GRADE rated
4
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 4 · 100%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

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Intrauterine administration of hCG for women undergoing assisted reproduction

Population: subfertile women undergoing assisted reproduction
4 questions
OutcomeEffectEvidenceStatus / GRADE
Live birth Cleavage stage: hCG < 500 IU
RR 0.76 [0.58, 1.01]1 study · 280 participantsVery low
Downgraded: risk of bias, imprecision
Miscarriage
RR 1.04 [0.81, 1.35]11 studies · 3927 participantsVery low
Downgraded: risk of bias, imprecision
Clinical pregnancy Cleavage stage: hCG < 500 IU
RR 0.88 [0.7, 1.1]1 study · 280 participantsVery low
Downgraded: risk of bias, imprecision
Complications
no estimate extracted7 studies · 1764 participantsVery low
Downgraded: risk of bias, imprecision