Cochrane · systematic review · CD008815
Progestin‐only contraceptives: effects on weight
Lopez, LM, Ramesh, S, Chen, M, et al. · Cochrane Database of Systematic Reviews · 2016 · Cochrane Library
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
7
current version
GRADE rated
6
No studies
1
Included studies
NR
No studies 1 · 14.3%Ungraded 0 · 0%Very low 0 · 0%Low 5 · 71.4%Moderate 1 · 14.3%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Current version onlyComparison
Population: women with need for contraception
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Change in body fat (%) by 6 months; change in lean body mass (%) by 6 months | MD 11 [2.64, 19.36] | 26 participants | Low |
Change in weight (kg): 1 year; 2 years; 3 years | MD 2.28 [1.79, 2.77] | 758 participants | Low |
Change in weight (kg): 1 year; 4 years; 10 years | no estimate extracted | 1277 participants | Low |
Comparison
Population: women with need for contraception
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Change in fat mass (%); change in lean mass (%) | no estimate extracted | 76 participants | Moderate |
Change in fat mass (%); change in fat free mass (%) | MD 1.6 [0.45, 2.75] | 60 participants | Low |
Comparison
Population: perimenopausal women with need for contraception
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Change in fat mass (%); change in fat free mass (%) | MD 3.3 [2.08, 4.52] | 68 participants | Low |
OC: oral contraceptive | no estimate extracted | NR | No studies |
Quality of evidence by contraceptive method
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Progestin‐only pills | no estimate extracted | NR | No studies |
OC NET 350 µg vs LNG 30 µg | no estimate extracted | NR | High |
DMPA | no estimate extracted | NR | No studies |
DMPA vs NET‐EN (60 days) | no estimate extracted | NR | High |
NET‐EN: 60 days vs 84 days | no estimate extracted | NR | High |
DMPA vs NET‐EN | no estimate extracted | NR | High |
DMPA + placebo vs DMPA + E2C | no estimate extracted | NR | Moderate |
DMPA + placebo vs no hormonal | no estimate extracted | NR | Moderate |
DMPA‐IM150 vs DMPA‐SC 104 | no estimate extracted | NR | Moderate |
DMPA 150 vs DMPA 450 | no estimate extracted | NR | Low |
DMPA vs IUD | no estimate extracted | NR | Low |
DMPA vs COC | no estimate extracted | NR | Low |
DMPA vs MPA/E2C | no estimate extracted | NR | Very low |
DMPA: interval vs postpartum | no estimate extracted | NR | Very low |
Norplant | no estimate extracted | NR | No studies |
Norplant vs 2‐rod LNG | no estimate extracted | NR | High |
Norplant vs IUD | no estimate extracted | NR | Moderate |
Norplant vs other non‐hormonal | no estimate extracted | NR | Moderate |
Norplant vs DMPA | no estimate extracted | NR | Low |
Norplant vs COC | no estimate extracted | NR | Very low |