Cochrane · systematic review · CD008815

Progestin‐only contraceptives: effects on weight

Lopez, LM, Ramesh, S, Chen, M, et al. · Cochrane Database of Systematic Reviews · 2016 · Cochrane Library

Fertility Regulation2 versionsAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
7
current version
GRADE rated
6
No studies
1
Included studies
NR
No studies 1 · 14.3%Ungraded 0 · 0%Very low 0 · 0%Low 5 · 71.4%Moderate 1 · 14.3%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Show all 2 versions

Comparison

Population: women with need for contraception
3 questions
OutcomeEffectEvidenceStatus / GRADE
Change in body fat (%) by 6 months; change in lean body mass (%) by 6 months
MD 11 [2.64, 19.36]26 participantsLow
Change in weight (kg): 1 year; 2 years; 3 years
MD 2.28 [1.79, 2.77]758 participantsLow
Change in weight (kg): 1 year; 4 years; 10 years
no estimate extracted1277 participantsLow

Comparison

Population: women with need for contraception
2 questions
OutcomeEffectEvidenceStatus / GRADE
Change in fat mass (%); change in lean mass (%)
no estimate extracted76 participantsModerate
Change in fat mass (%); change in fat free mass (%)
MD 1.6 [0.45, 2.75]60 participantsLow

Comparison

Population: perimenopausal women with need for contraception
2 questions
OutcomeEffectEvidenceStatus / GRADE
Change in fat mass (%); change in fat free mass (%)
MD 3.3 [2.08, 4.52]68 participantsLow
OC: oral contraceptive
no estimate extractedNRNo studies