Cochrane · systematic review · CD007263

Dilute versus full‐strength formula in exclusively formula‐fed preterm or low birth weight infants

Basuki, F, Hadiati, DR, Turner, T, et al. · Cochrane Database of Systematic Reviews · 2019 · Cochrane Library

Neonatal2 versionsAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
6
current version
GRADE rated
3
No studies
3
Included studies
NR
No studies 3 · 50%Ungraded 0 · 0%Very low 0 · 0%Low 3 · 50%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Current version only

Half‐strength formula compared to full‐strength formula for exclusively formula‐fed preterm or low birth weight infants

Population: exclusively formula‐fed preterm or low birth weight infants
CD007263.PUB3 (current) · 6 questions
OutcomeEffectEvidenceStatus / GRADE
Episodes of abdominal distention > 2 cm
Half‐strength formula vs full‐strength formula
no estimate extracted2 studies · 88 participantsLow
Downgraded: risk of bias, imprecision
Episodes of gastric residuals3> 50% of last feed remaining
Half‐strength formula vs full‐strength formula
no estimate extracted2 studies · 88 participantsLow
Downgraded: risk of bias, imprecision
Days until 420 joules per kilogram
Half‐strength formula vs full‐strength formula
no estimate extracted2 studies · 88 participantsLow
Downgraded: risk of bias, imprecision
Necrotising enterocolitis
Half‐strength formula vs full‐strength formula
no estimate extractedNRNo studies
All‐cause mortality prior to hospital discharge
Half‐strength formula vs full‐strength formula
no estimate extractedNRNo studies
Incidence of invasive infection
Half‐strength formula vs full‐strength formula
no estimate extractedNRNo studies

Half strength formula compared to full strength formula for exclusively formula‐fed preterm or low birth weight infants

Population: exclusively formula‐fed preterm or low birth weight infants
CD007263.PUB2 · 6 questions
OutcomeEffectEvidenceStatus / GRADE
Episodes of abdominal distention > 2 cm
Half strength formula vs full strength formula
no estimate extracted2 studies · 88 participantsLow
Downgraded: risk of bias, imprecision
Episodes of gastric residuals3 > 50% of last feed remaining
Half strength formula vs full strength formula
no estimate extracted2 studies · 88 participantsLow
Downgraded: risk of bias, imprecision
Days until 420 joules per kilogram days
Half strength formula vs full strength formula
no estimate extracted2 studies · 88 participantsLow
Downgraded: risk of bias, imprecision
Necrotising enterocolitis
Half strength formula vs full strength formula
no estimate extracted0 studies · 0 participantsUngraded
All‐cause mortality prior to hospital discharge
Half strength formula vs full strength formula
no estimate extracted0 studies · 0 participantsUngraded
Incidence of invasive infection
Half strength formula vs full strength formula
no estimate extracted0 studies · 0 participantsUngraded