Cochrane · systematic review · CD001457
Glutamine supplementation to prevent morbidity and mortality in preterm infants
Moe‐Byrne, T, Brown, JVE, McGuire, W · Cochrane Database of Systematic Reviews · 2016 · Cochrane Library
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
4
current version
GRADE rated
4
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 0 · 0%Low 1 · 25%Moderate 2 · 50%High 1 · 25%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Current version onlyGlutamine supplementation to prevent morbidity and mortality in preterm infants
Population: Preterm infants
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Death prior to hospital discharge | RR 0.97 [0.8, 1.17] | 12 studies · 2877 participants | High |
Neurodevelopmental impairment | RR 1.07 [0.59, 1.92] | 1 study · 72 participants | Low Downgraded: imprecision, inconsistency, publication bias |
Invasive infection | RR 0.94 [0.86, 1.04] | 11 studies · 2815 participants | Moderate Downgraded: imprecision, inconsistency, publication bias |
Necrotising enterocolitis | RR 0.83 [0.66, 1.06] | 11 studies · 2849 participants | Moderate Downgraded: imprecision, inconsistency, publication bias |
Glutamine supplementation to prevent morbidity and mortality in preterm infants
Population: Preterm infants
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Death prior to hospital discharge | RR 0.97 [0.8, 1.17] | 12 studies · 2877 participants | High |
Neurodevelopmental impairment | RR 1.07 [0.59, 1.92] | 1 study · 72 participants | Low Downgraded: imprecision, inconsistency, publication bias |
Invasive infection | RR 0.94 [0.86, 1.04] | 11 studies · 2815 participants | Moderate Downgraded: imprecision, inconsistency, publication bias |
Necrotising enterocolitis | RR 0.83 [0.66, 1.06] | 11 studies · 2849 participants | Moderate Downgraded: imprecision, inconsistency, publication bias |