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Evidence found and GRADE certainty

1,332 questions · 1,350 findings · 123 reviews · Anaesthesia · Headline outcomes only

No studies found 157 · 11.6%GRADE not reported 187 · 13.9%Very low 277 · 20.5%Low 418 · 31%Moderate 241 · 17.9%High 70 · 5.2%

Summary of findings ‐ Erector spinae plane block vs serratus anterior plane block

Rates of block‐related adverse events · adults undergoing surgery with general anaesthesia

Summary of findings ‐ Erector spinae plane block showed no clear difference in rates of block‐related adverse events compared with serratus anterior plane block (low certainty).

1 finding from 1 review

Summary of findings ‐ Erector spinae plane block vs intercostal nerve block

Rates of block‐related adverse events · adults undergoing surgery with general anaesthesia

It is very uncertain whether summary of findings ‐ Erector spinae plane block changes rates of block‐related adverse events compared with intercostal nerve block (very low certainty).

1 finding from 1 review

Summary of findings ‐ Erector spinae plane block vs paravertebral block

Rates of block‐related adverse events · adults undergoing surgery with general anaesthesia

Summary of findings ‐ Erector spinae plane block probably leads to lower rates of block‐related adverse events compared with paravertebral block (moderate certainty).

1 finding from 1 review

Summary of findings ‐ Erector spinae plane block vs transversus abdominis plane block

Rates of block‐related adverse events · adults undergoing surgery with general anaesthesia

Summary of findings ‐ Erector spinae plane block showed no clear difference in rates of block‐related adverse events compared with transversus abdominis plane block (low certainty).

1 finding from 1 review

Automated mandatory bolus vs basal infusion

Breakthrough pain · term, pregnant women (nulliparous, or combination of nulli‐ and muliparous) requesting for labour epidural analgesia

Automated mandatory bolus probably leads to lower breakthrough pain compared with basal infusion (moderate certainty).

1 finding from 1 review

Automated mandatory bolus vs basal infusion

Caesarean delivery during labour epidural analgesia · term, pregnant women (nulliparous, or combination of nulli‐ and muliparous) requesting for labour epidural analgesia

Automated mandatory bolus showed no clear difference in caesarean delivery during labour epidural analgesia compared with basal infusion (moderate certainty).

1 finding from 1 review