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What do systematic reviews say?

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Evidence found and GRADE certainty

3 questions · 3 findings · 1 reviews · Movement Disorders

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No studies found 0 · 0%GRADE not reported 0 · 0%Very low 3 · 100%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Zonisamide vs placebo

Functional abilities Change in TRS part B score (motor tasks) Change in TRS part C score (functional disability) (higher scores indicate a better outcome) · patients with essential tremor

It is very uncertain whether zonisamide changes functional abilities Change in TRS part B score (motor tasks) Change… compared with placebo (very low certainty).

1 finding from 1 review

Zonisamide vs placebo

Study Withdrawals · patients with essential tremor

It is very uncertain whether zonisamide changes study withdrawal for any reason Number of participants withdrawn… compared with placebo (very low certainty).

1 finding from 1 review

Zonisamide vs placebo

Adverse events Number of adverse events · patients with essential tremor

It is very uncertain whether zonisamide changes adverse events Number of adverse events compared with placebo (very low certainty).

1 finding from 1 review