Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

22 questions · 22 findings · 2 reviews · Headline outcomes only

No studies found 5 · 22.7%GRADE not reported 3 · 13.6%Very low 0 · 0%Low 1 · 4.5%Moderate 9 · 40.9%High 4 · 18.2%

Topical vitamin D derivative vs placebo

Proportion of participants with adverse effects ‐ measured over 8 weeks · chronic palmoplantar pustulosis

Topical vitamin D derivative showed no clear difference in proportion of participants with adverse effects ‐ measured over 8… compared with placebo (moderate certainty).

1 finding from 1 review

Topical vitamin D derivative vs placebo

Proportion of participants cleared or almost cleared ‐ · chronic palmoplantar pustulosis

Topical vitamin D derivative may leads to higher proportion of participants cleared or almost cleared in the short… compared with placebo (low certainty).

1 finding from 1 review

Steroid plus vitamin D vs vitamin D

Number of participants achieving 'clearance' by IGA · scalp psoriasis

Steroid plus vitamin D leads to higher number of participants achieving 'clearance' by IGA compared with vitamin D (high certainty).

1 finding from 1 review

Steroid plus vitamin D vs vitamin D

Number of participants achieving 'response' by IGA · scalp psoriasis

Steroid plus vitamin D probably leads to higher number of participants achieving 'response' by IGA compared with vitamin D (moderate certainty).

1 finding from 1 review

Steroid plus vitamin D vs vitamin D

Number of participants withdrawing due to adverse events (AE) · scalp psoriasis

Steroid plus vitamin D leads to lower number of participants withdrawing due to adverse events compared with vitamin D (high certainty).

1 finding from 1 review

Steroid plus vitamin D vs vitamin D

Number of participants achieving 'response' by PGA · scalp psoriasis

Steroid plus vitamin D probably leads to higher number of participants achieving 'response' by PGA compared with vitamin D (moderate certainty).

1 finding from 1 review

Steroid plus vitamin D vs steroids

Number of participants achieving 'response' by PGA · scalp psoriasis

Steroid plus vitamin D leads to higher number of participants achieving 'response' by PGA compared with steroid (high certainty).

1 finding from 1 review

Steroid plus vitamin D vs steroids

Number of participants achieving 'clearance' by IGA · scalp psoriasis

Steroid plus vitamin D probably leads to higher number of participants achieving 'clearance' by IGA compared with steroid (moderate certainty).

1 finding from 1 review

Steroid plus vitamin D vs steroids

Number of participants achieving 'response' by IGA · scalp psoriasis

Steroid plus vitamin D probably leads to higher number of participants achieving 'response' by IGA compared with steroid (moderate certainty).

1 finding from 1 review

Steroid plus vitamin D vs steroids

Number of participants withdrawing due to adverse events (AE) · scalp psoriasis

Steroid plus vitamin D showed no clear difference in number of participants withdrawing due to adverse events (AE) compared with steroid (moderate certainty).

1 finding from 1 review

Steroids vs vitamin D

Number of participants achieving 'clearance' by IGA · scalp psoriasis

Steroid probably leads to higher number of participants achieving 'clearance' by IGA compared with vitamin D (moderate certainty).

1 finding from 1 review

Steroids vs vitamin D

Number of participants achieving 'response' by IGA · scalp psoriasis

Steroid leads to higher number of participants achieving 'response' by IGA compared with vitamin D (high certainty).

1 finding from 1 review