Findings

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Evidence found and GRADE certainty

57 questions · 60 findings · 5 reviews · Neonatal

No studies found 0 · 0%GRADE not reported 0 · 0%Very low 8 · 13.3%Low 36 · 60%Moderate 9 · 15%High 7 · 11.7%

Vitamin D given to infants vs vitamin D given to lactating mothers

Vitamin D insufficiency: 25‐OH vitamin D < 50 nmol/L · term breastfed infants to prevent vitamin D deficiency and improve bone health

It is very uncertain whether vitamin D given to infants changes vitamin D insufficiency: 25‐OH vitamin D < 50 nmol/L compared with vitamin D given to lactating mothers (very low certainty).

1 finding from 1 review

Vitamin D given to infants vs vitamin D given to lactating mothers

Vitamin D deficiency: 25‐OH vitamin D < 30 nmol/L · term breastfed infants to prevent vitamin D deficiency and improve bone health

It is very uncertain whether vitamin D given to infants changes vitamin D deficiency: 25‐OH vitamin D < 30 nmol/L compared with vitamin D given to lactating mothers (very low certainty).

1 finding from 1 review

Vitamin D given to infants vs placebo or no treatment

Vitamin D insufficiency: 25‐OH vitamin D < 50 nmol/L · term breastfed infants to prevent vitamin D deficiency and improve bone health

Vitamin D given to infants may leads to lower vitamin D insufficiency: 25‐OH vitamin D < 50 nmol/L compared with placebo or no treatment (low certainty).

1 finding from 1 review

Vitamin D given to infants vs placebo or no treatment

Vitamin D deficiency: 25‐OH vitamin D < 30 nmol/L · term breastfed infants to prevent vitamin D deficiency and improve bone health

It is very uncertain whether vitamin D given to infants changes vitamin D deficiency: 25‐OH vitamin D < 30 nmol/L compared with placebo or no treatment (very low certainty).

1 finding from 1 review

Vitamin D given to lactating mothers vs placebo or no treatment

Vitamin D insufficiency: 25‐OH vitamin D < 50 nmol/L · term breastfed infants to prevent vitamin D deficiency and improve bone health

Vitamin D given to lactating mothers may leads to lower vitamin D insufficiency: 25‐OH vitamin D < 50 nmol/L compared with placebo or no treatment (low certainty).

1 finding from 1 review

Vitamin D given to lactating mothers vs placebo or no treatment

Vitamin D deficiency: 25‐OH vitamin D < 30 nmol/L · term breastfed infants to prevent vitamin D deficiency and improve bone health

Vitamin D given to lactating mothers may leads to lower vitamin D deficiency: 25‐OH vitamin D < 30 nmol/L compared with placebo or no treatment (low certainty).

1 finding from 1 review

Vitamin D given to infants vs vitamin D given to lactating mothers

Hypercalcaemia · term breastfed infants to prevent vitamin D deficiency and improve bone health

Vitamin D given to infants showed no clear difference in adverse effect (hypercalcaemia) compared with vitamin D given to lactating mothers (low certainty).

1 finding from 1 review

Neonatal vitamin A supplementation vs control

Vitamin A deficiency · mortality and morbidity in term neonates

Neonatal vitamin A supplementation showed no clear difference in vitamin A deficiency (serum retinol < 0.70 micromol/L) at 6 weeks of… compared with control (high certainty).

2 findings from 1 review

Higher dose vitamin K vs lower dose vitamin K

Intraventricular hemorrhage > Grade II: 0.2 mg IM versus 0.5 mg IM · preterm infants

Higher dose vitamin K showed no clear difference in intraventricular hemorrhage > Grade II: 0.2 mg IM versus 0.5 mg IM compared with lower dose vitamin K (low certainty).

1 finding from 1 review