Vasodilator side effects · women undergoing fertility treatment
Vasodilator probably leads to higher vasodilator side effects compared with placebo or no treatment (moderate certainty).
1 finding from 1 review
Live birth · women undergoing fertility treatment
Vasodilator showed no clear difference in live birth compared with placebo or no treatment (moderate certainty).
1 finding from 1 review
Clinical pregnancy · women undergoing fertility treatment
Vasodilator may leads to higher clinical pregnancy compared with placebo or no treatment (low certainty).
1 finding from 1 review
Thickened endometrium · women undergoing fertility treatment
1 finding from 1 review
Multiple gestation or birth · women undergoing fertility treatment
Vasodilator showed no clear difference in multiple gestation or birth compared with placebo or no treatment (low certainty).
1 finding from 1 review
Miscarriage · women undergoing fertility treatment
Vasodilator showed no clear difference in spontaneous miscarriage compared with placebo or no treatment (low certainty).
1 finding from 1 review
Ectopic pregnancy · women undergoing fertility treatment
Vasodilator showed no clear difference in ectopic pregnancy compared with placebo or no treatment (low certainty).
1 finding from 1 review
Maximal mouth opening (interincisal distance) · People of any age with a confirmed diagnosis, by clinical examination and biopsy, of oral submucous fibrosis (OSF)
It is very uncertain whether vasodilators (isoxsuprine, xanthinol nicotinate) changes maximal mouth opening (interincisal distance) compared with placebo or no active treatment (very low certainty).
2 findings from 1 review
Burning sensation (VAS 0-100) · People of any age with a confirmed diagnosis, by clinical examination and biopsy, of oral submucous fibrosis (OSF)
It is very uncertain whether vasodilators (isoxsuprine, xanthinol nicotinate) changes burning sensation (VAS 0-100) compared with placebo or no active treatment (very low certainty).
2 findings from 1 review
MD -51.02 [-72.85, -29.20]
2 studies · 85 participants
Very low
MD -38.79 [-52.06, -25.53]
2 studies · 85 participants
Very low
Adverse effects · People of any age with a confirmed diagnosis, by clinical examination and biopsy, of oral submucous fibrosis (OSF)
1 finding from 1 review
Intervention not reported
Aldosterone antagonists plus loop diuretics plus systemic vasoconstrictors plus systemic vasodilator (No direct RCT) · people with liver cirrhosis and ascites
It is very uncertain whether the intervention changes aldosterone antagonists plus loop diuretics plus systemic… (very low certainty).
1 finding from 1 review
HR 0.61 [0.02, 9.17]
Studies not reported
Very low
Intervention not reported
Aldosterone antagonists plus loop diuretics plus systemic vasodilator (No direct RCT) · people with liver cirrhosis and ascites
It is very uncertain whether the intervention changes aldosterone antagonists plus loop diuretics plus systemic… (very low certainty).
1 finding from 1 review
HR 0.62 [0.03, 9.1]
Studies not reported
Very low
Migraine frequency Number of attacks · primary Raynaud's phenomenon
1 finding from 1 review
QoL · primary Raynaud's phenomenon
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Adverse events (4 weeks' to 180 days' · primary Raynaud's phenomenon
1 finding from 1 review
RCS · primary Raynaud's phenomenon
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Migraine frequency Number of attacks · primary Raynaud's phenomenon
1 finding from 1 review
Severity of attacks · primary Raynaud's phenomenon
1 finding from 1 review
Duration of attacks · primary Raynaud's phenomenon
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
QoL · primary Raynaud's phenomenon
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found