Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

90 questions · 93 findings · 20 reviews · Headline outcomes only

No studies found 8 · 8.6%GRADE not reported 3 · 3.2%Very low 26 · 28%Low 35 · 37.6%Moderate 19 · 20.4%High 2 · 2.2%

Closest answers

The findings closest to your search, judged one by one by TypeSafe's Jev model.

Cognitive‐behavioural intervention vs unspecific control

ADHD symptoms · adults with ADHD (available evidence for participants aged between 25 to 53 years old)
2 findings from 1 review

Cognitive‐behavioural intervention vs unspecific control

ADHD symptoms: self‐reported Assessed by: various scales · adults with ADHD (available evidence for participants aged between 25 to 53 years old)
2 findings from 1 review

Augmentation of current antidepressant (various) with cariprazine (1 mg/d to 4.5 mg/d) vs augmentation of current antidepressant (various) with placebo

Dropouts ‐ Any dose · treatment‐resistant depression in adults

Augmentation of current antidepressant (various) with cariprazine (1… probably leads to higher dropouts ‐ any dose compared with augmentation of current antidepressant (various) with placebo (moderate certainty).

1 finding from 1 review

Augmentation of current antidepressant (various) with cariprazine (1 mg/d to 4.5 mg/d) vs augmentation of current antidepressant (various) with placebo

> 50% reduction in depressive symptoms · treatment‐resistant depression in adults

Augmentation of current antidepressant (various) with cariprazine (1… probably leads to higher response (≥ 50% improvement in MADRS score) ‐ any dose compared with augmentation of current antidepressant (various) with placebo (moderate certainty).

1 finding from 1 review