Findings

What do systematic reviews say?

5 questions · 7 findings · 1 reviews · Dementia and Cognitive Improvement

No studies found 0 · 0%GRADE not reported 0 · 0%Very low 3 · 42.9%Low 1 · 14.3%Moderate 3 · 42.9%High 0 · 0%

Behavioural problems: agitation or aggression · people with agitation in dementia

3 findings from 1 review

Valproate preparations for agitation in dementia 2018 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 202 participants
Moderate
Valproate preparations for agitation in dementia 2018 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 202 participants
Moderate
Valproate preparations for agitation in dementia 2018 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 217 participants
Very low

Cognitive function · people with agitation in dementia

1 finding from 1 review

Valproate preparations for agitation in dementia 2018 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 217 participants
Very low

Functional performance · people with agitation in dementia

1 finding from 1 review

Valproate preparations for agitation in dementia 2018 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 203 participants
Moderate

Any adverse event by 6 weeks · people with agitation in dementia

Valproate preparations may leads to higher any adverse event by 6 weeks compared with placebo (low certainty).

1 finding from 1 review

Valproate preparations for agitation in dementia 2018 · Cochrane Headline outcomes only
OR 2.02 [1.3, 3.14]
3 studies · 381 participants
Low

Serious adverse events by 6 weeks · people with agitation in dementia

It is very uncertain whether valproate preparations changes serious adverse events by 6 weeks compared with placebo (very low certainty).

1 finding from 1 review

Valproate preparations for agitation in dementia 2018 · Cochrane Headline outcomes only
OR 4.77 [1, 22.74]
2 studies · 228 participants
Very low