Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

80 questions · 84 findings · 9 reviews

No studies found 19 · 22.6%GRADE not reported 3 · 3.6%Very low 12 · 14.3%Low 40 · 47.6%Moderate 10 · 11.9%High 0 · 0%

Vaginal misoprostol vs placebo

Opiate use (as a proxy measure for pain) for all participants on ITT (including those without confirmed AMI) · early fetal death (less than 24 weeks)

It is very uncertain whether vaginal misoprostol changes pain (opiate use) compared with placebo (very low certainty).

1 finding from 1 review