Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

9 questions · 9 findings · 1 reviews · Gut · Headline outcomes only

No studies found 0 · 0%GRADE not reported 0 · 0%Very low 1 · 11.1%Low 2 · 22.2%Moderate 6 · 66.7%High 0 · 0%

Tranexamic acid vs placebo

Thromboembolic events · patients with upper gastrointestinal bleeding

Tranexamic acid probably leads to higher any thromboembolic event Clinical and radiological assessment compared with placebo (moderate certainty).

1 finding from 1 review

Tranexamic acid vs placebo

Surgery Number of participants who underwent surgery · patients with upper gastrointestinal bleeding

Tranexamic acid probably leads to lower surgery Number of participants who underwent surgery compared with placebo (moderate certainty).

1 finding from 1 review

Tranexamic acid vs placebo

Blood transfusion · patients with upper gastrointestinal bleeding

It is very uncertain whether tranexamic acid changes transfusion Number needing blood transfusion compared with placebo (very low certainty).

1 finding from 1 review