Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

61 questions · 63 findings · 6 reviews · Headline outcomes only

No studies found 29 · 46%GRADE not reported 0 · 0%Very low 23 · 36.5%Low 8 · 12.7%Moderate 3 · 4.8%High 0 · 0%

Silver‐based antiseptics vs topical antibiotics

Time to complete healing · people with burns

Silver‐based antiseptics showed no clear difference in wound healing: time to complete healing (time‐to‐event data) compared with topical antibiotics (low certainty).

1 finding from 1 review
  • Antiseptics for burns 2017 · Cochrane Headline outcomes only
    HR 1.25 [0.94, 1.67]
    3 studies · 259 participants
    Low

Silver‐based antiseptics vs topical antibiotics

Wound healing · people with burns

Silver‐based antiseptics showed no clear difference in wound healing (mean time to healing) compared with topical antibiotics (low certainty).

1 finding from 1 review
  • Antiseptics for burns 2017 · Cochrane Headline outcomes only
    no estimate extracted
    10 studies · 1085 participants
    Low

Silver‐based antiseptics vs topical antibiotics

Number of wounds healed · people with burns

Silver‐based antiseptics showed no clear difference in wound healing (number of healing events) compared with topical antibiotics (low certainty).

1 finding from 1 review
  • Antiseptics for burns 2017 · Cochrane Headline outcomes only
    RR 1.17 [1, 1.37]
    5 studies · 408 participants
    Low

Topical antibiotics vs antiseptic agent

Allergic contact dermatitis · people presenting for surgery where healing of surgical wound planned to be by primary intention

It is very uncertain whether topical antibiotics changes allergic contact dermatitis compared with antiseptic (very low certainty).

1 finding from 1 review