Findings

What do systematic reviews say?

30 questions · 30 findings · 5 reviews

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No studies found 7 · 23.3%GRADE not reported 0 · 0%Very low 3 · 10%Low 10 · 33.3%Moderate 9 · 30%High 1 · 3.3%

Closest answers

The findings closest to your search, judged one by one by TypeSafe's Jev model.

Direct match · question page
- Topical local anaesthetic (spray or dental swab) vs Placebo or no treatment · Postoperative pain or distress
  Intraoperative local anaesthesia for reduction of postoperative pain following general anaesthesia for dental… 2014 · Cochrane All outcomes
  Postoperatively, typically up to discharge (5 to 60 minutes)
  Because of substantial clinical and methodological heterogeneity in the studies, we were unable to determine an estimate of effect
  4 studies · 343 participants
  Very low
Direct match · question page
- Topical anaesthesia vs sub‐Tenon's anaesthesia · Intraoperative pain
  Sub‐Tenon's anaesthesia versus topical anaesthesia for cataract surgery 2015 · Cochrane Headline outcomes only
  no estimate extracted
  3 studies · 501 participants
  High
Direct match · question page
- Topical anaesthesia vs sub‐Tenon's anaesthesia · Participant satisfaction
  Sub‐Tenon's anaesthesia versus topical anaesthesia for cataract surgery 2015 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 26 participants
  Moderate
Direct match · question page
- Topical anaesthesia vs sub‐Tenon's anaesthesia · Pain at 24 hours
  Sub‐Tenon's anaesthesia versus topical anaesthesia for cataract surgery 2015 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 200 participants
  Moderate
Direct match · question page
- Topical anaesthesia vs sub‐Tenon's anaesthesia · Surgeon's satisfaction Scale from 0 to 10
  Sub‐Tenon's anaesthesia versus topical anaesthesia for cataract surgery 2015 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 200 participants
  Low

Topical anaesthesia vs sub‐Tenon's anaesthesia

Pain during administration of anaesthesia · patients undergoing cataract surgery

1 finding from 1 review

Sub‐Tenon's anaesthesia versus topical anaesthesia for cataract surgery 2015 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 184 participants
Low

Topical anaesthesia plus intracameral lidocaine vs topical anaesthesia alone

Need for additional anaesthesia during surgery Assessed dichotomously, as 'additional anaesthesia given' or 'additional anaesthesia not given' · adults undergoing phacoemulsification cataract surgery

Topical anaesthesia plus intracameral lidocaine showed no clear difference in need for additional anaesthesia during surgery Assessed… compared with topical anaesthesia alone (low certainty).

1 finding from 1 review

Topical anaesthesia plus intracameral lidocaine versus topical anaesthesia alone for phacoemulsification cataract… 2020 · Cochrane Headline outcomes only
OR 0.88 [0.56, 1.39]
Studies not reported
Low

Topical anaesthesia plus intracameral lidocaine vs topical anaesthesia alone

Intraoperative adverse surgical events attributable to choice of anaesthesia · adults undergoing phacoemulsification cataract surgery

Topical anaesthesia plus intracameral lidocaine showed no clear difference in intraoperative adverse surgical events attributable to choice of… compared with topical anaesthesia alone (low certainty).

1 finding from 1 review

Topical anaesthesia plus intracameral lidocaine versus topical anaesthesia alone for phacoemulsification cataract… 2020 · Cochrane Headline outcomes only
OR 1 [0.32, 3.16]
Studies not reported
Low

Topical anaesthesia vs sub‐Tenon's anaesthesia

Intraoperative pain · patients undergoing cataract surgery

1 finding from 1 review

Sub‐Tenon's anaesthesia versus topical anaesthesia for cataract surgery 2015 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 501 participants
High

Topical anaesthesia vs sub‐Tenon's anaesthesia

Pain at 24 hours · patients undergoing cataract surgery

1 finding from 1 review

Sub‐Tenon's anaesthesia versus topical anaesthesia for cataract surgery 2015 · Cochrane Headline outcomes only
no estimate extracted
1 study · 200 participants
Moderate

Topical anaesthesia vs sub‐Tenon's anaesthesia

Surgeon's satisfaction Scale from 0 to 10 · patients undergoing cataract surgery

1 finding from 1 review

Sub‐Tenon's anaesthesia versus topical anaesthesia for cataract surgery 2015 · Cochrane Headline outcomes only
no estimate extracted
1 study · 200 participants
Low

Topical anaesthesia vs sub‐Tenon's anaesthesia

Participant satisfaction · patients undergoing cataract surgery

1 finding from 1 review

Sub‐Tenon's anaesthesia versus topical anaesthesia for cataract surgery 2015 · Cochrane Headline outcomes only
no estimate extracted
1 study · 26 participants
Moderate

Topical anaesthesia plus intracameral lidocaine vs topical anaesthesia alone

Intraoperative pain or discomfort (continuous data) · adults undergoing phacoemulsification cataract surgery

1 finding from 1 review

Topical anaesthesia plus intracameral lidocaine versus topical anaesthesia alone for phacoemulsification cataract… 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Moderate

Topical anaesthesia plus intracameral lidocaine vs topical anaesthesia alone

Intraoperative pain or discomfort (dichotomous data) · adults undergoing phacoemulsification cataract surgery

Topical anaesthesia plus intracameral lidocaine probably leads to lower intraoperative pain or discomfort (dichotomous data) compared with topical anaesthesia alone (moderate certainty).

1 finding from 1 review

Topical anaesthesia plus intracameral lidocaine versus topical anaesthesia alone for phacoemulsification cataract… 2020 · Cochrane Headline outcomes only
OR 0.4 [0.29, 0.57]
Studies not reported
Moderate

Topical anaesthesia plus intracameral lidocaine vs topical anaesthesia alone

Discomfort/pain · adults undergoing phacoemulsification cataract surgery

1 finding from 1 review

Topical anaesthesia plus intracameral lidocaine versus topical anaesthesia alone for phacoemulsification cataract… 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Moderate

Topical anaesthesia plus intracameral lidocaine vs topical anaesthesia alone

Participant satisfaction · adults undergoing phacoemulsification cataract surgery

1 finding from 1 review

Topical anaesthesia plus intracameral lidocaine versus topical anaesthesia alone for phacoemulsification cataract… 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Low

Topical anaesthesia plus intracameral lidocaine vs topical anaesthesia alone

Mean change of endothelial cell loss · adults undergoing phacoemulsification cataract surgery

1 finding from 1 review

Topical anaesthesia plus intracameral lidocaine versus topical anaesthesia alone for phacoemulsification cataract… 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Moderate

Primary outcome: topical local anaesthetics vs placebo or no treatment

Postoperative pain or distress · Children and young people aged 17 years or younger having dental treatment (including extractions) under general anaesthesia (secondary…

1 finding from 1 review

Intraoperative local anaesthesia for reduction of postoperative pain following general anaesthesia for dental… 2014 · Cochrane All outcomes
Postoperatively, typically up to discharge (5 to 60 minutes)
Because of substantial clinical and methodological heterogeneity in the studies, we were unable to determine an estimate of effect
4 studies · 343 participants
Very low

Primary outcome: topical local anaesthetics vs placebo or no treatment

Physiological parameters (cardiac/respiratory events; type and volume of GA drug) · Children and young people aged 17 years or younger having dental treatment (including extractions) under general anaesthesia (secondary…

The review found no eligible studies for this question.

1 finding from 1 review

Intraoperative local anaesthesia for reduction of postoperative pain following general anaesthesia for dental… 2014 · Cochrane All outcomes
None of the studies reported on this outcome
0 studies
No studies found

Primary outcome: topical local anaesthetics vs placebo or no treatment

Lip or cheek biting · Children and young people aged 17 years or younger having dental treatment (including extractions) under general anaesthesia (secondary…

The review found no eligible studies for this question.

1 finding from 1 review

Intraoperative local anaesthesia for reduction of postoperative pain following general anaesthesia for dental… 2014 · Cochrane All outcomes
None of the studies reported on lip or cheek biting
0 studies
No studies found

Primary outcome: topical local anaesthetics vs placebo or no treatment

Intraoperative or postoperative bleeding · Children and young people aged 17 years or younger having dental treatment (including extractions) under general anaesthesia (secondary…

1 finding from 1 review

Intraoperative local anaesthesia for reduction of postoperative pain following general anaesthesia for dental… 2014 · Cochrane All outcomes
Elhakim 1993 reported prolonged postoperative bleeding in the no-treatment group; Andrzejowski 2002 reported no difference in bleeding (nurse-assessed 'mild' in both groups)
2 studies · 160 participants
Very low

Primary outcome: topical local anaesthetics vs placebo or no treatment

Parental satisfaction · Children and young people aged 17 years or younger having dental treatment (including extractions) under general anaesthesia (secondary…

The review found no eligible studies for this question.

1 finding from 1 review

Intraoperative local anaesthesia for reduction of postoperative pain following general anaesthesia for dental… 2014 · Cochrane All outcomes
No study reported parental satisfaction
0 studies
No studies found

Primary outcome: topical local anaesthetics vs placebo or no treatment

Participant satisfaction · Children and young people aged 17 years or younger having dental treatment (including extractions) under general anaesthesia (secondary…

The review found no eligible studies for this question.

1 finding from 1 review

Intraoperative local anaesthesia for reduction of postoperative pain following general anaesthesia for dental… 2014 · Cochrane All outcomes
None of the studies reported on patient or child satisfaction
0 studies
No studies found

Primary outcome: topical local anaesthetics vs placebo or no treatment

Postoperative anxiety · Children and young people aged 17 years or younger having dental treatment (including extractions) under general anaesthesia (secondary…

The review found no eligible studies for this question.

1 finding from 1 review

Intraoperative local anaesthesia for reduction of postoperative pain following general anaesthesia for dental… 2014 · Cochrane All outcomes
None of the studies reported on postoperative anxiety
0 studies
No studies found

Summary of findings table ‐ Topical cervical lidocaine spray vs ultracaine paracervical block

Pain with dilation ‐ not measured · people requesting a surgical abortion at 5+0 to 7+0 weeks' gestation

The review found no eligible studies for this question.

1 finding from 1 review

Local anaesthesia for pain control in first trimester surgical abortion 2024 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found