Findings

What do systematic reviews say?

15 questions · 15 findings · 3 reviews · Infectious Diseases · Headline outcomes only

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No studies found 5 · 33.3%GRADE not reported 0 · 0%Very low 2 · 13.3%Low 4 · 26.7%Moderate 4 · 26.7%High 0 · 0%

Tetracycline vs doxycycline

Duration of diarrhoea · Adults and children with cholera diarrhoea

1 finding from 1 review

Antimicrobial drugs for treating cholera 2014 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 230 participants
Moderate

Tetracycline vs doxycycline

Stool volume · Adults and children with cholera diarrhoea

1 finding from 1 review

Antimicrobial drugs for treating cholera 2014 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 336 participants
Moderate

Tetracycline vs doxycycline

Bacteriological failure · Adults and children with cholera diarrhoea

Tetracycline probably leads to lower bacteriological failure compared with doxycycline (moderate certainty).

1 finding from 1 review

Antimicrobial drugs for treating cholera 2014 · Cochrane Headline outcomes only
RR 0.2 [0.06, 0.68]
2 studies · 198 participants
Moderate

Tetracycline vs quinolones

Duration of diarrhoea · Adults and children with cholera diarrhoea

1 finding from 1 review

Antimicrobial drugs for treating cholera 2014 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 259 participants
Moderate

Tetracycline vs quinolones

Stool volume · Adults and children with cholera diarrhoea

1 finding from 1 review

Antimicrobial drugs for treating cholera 2014 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 236 participants
Low

Tetracycline vs quinolones

Bacteriological failure · Adults and children with cholera diarrhoea

Tetracycline showed no clear difference in bacteriological failure compared with quinolones (low certainty).

1 finding from 1 review

Antimicrobial drugs for treating cholera 2014 · Cochrane Headline outcomes only
RR 0.99 [0.14, 6.82]
2 studies · 234 participants
Low

Doxycycline vs tetracycline

Treatment failure · adults with scrub typhus

It is very uncertain whether doxycycline changes treatment failure compared with tetracycline (very low certainty).

1 finding from 1 review

Antibiotics for treating scrub typhus 2018 · Cochrane Headline outcomes only
RR 6.85 [0.38, 124.38]
1 study · 116 participants
Very low

Doxycycline vs tetracycline

Resolution of fever within 48 hours · adults with scrub typhus

Doxycycline showed no clear difference in resolution of fever within 48 hours compared with tetracycline (low certainty).

1 finding from 1 review

Antibiotics for treating scrub typhus 2018 · Cochrane Headline outcomes only
RR 1.14 [0.9, 1.44]
1 study · 55 participants
Low

Doxycycline vs tetracycline

Resolution of fever within 5 days · adults with scrub typhus

The review found no eligible studies for this question.

1 finding from 1 review

Antibiotics for treating scrub typhus 2018 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Doxycycline vs tetracycline

Time to defervescence · adults with scrub typhus

1 finding from 1 review

Antibiotics for treating scrub typhus 2018 · Cochrane Headline outcomes only
no estimate extracted
1 study · 116 participants
Low

Doxycycline vs tetracycline

Serious adverse events · adults with scrub typhus

The review found no eligible studies for this question.

1 finding from 1 review

Antibiotics for treating scrub typhus 2018 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Sulphonamides vs tetracycline

Diarrhoea · patients with Shigella dysentery

It is very uncertain whether sulphonamides changes diarrhoea at compared with tetracycline (very low certainty).

1 finding from 1 review

Antibiotic therapy for Shigella dysentery 2010 · Cochrane Headline outcomes only
RR 7.68 [0.46, 128.12]
1 study · 60 participants
Very low

Sulphonamides vs tetracycline

Relapse ‐ not reported · patients with Shigella dysentery

The review found no eligible studies for this question.

1 finding from 1 review

Antibiotic therapy for Shigella dysentery 2010 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Sulphonamides vs tetracycline

Serious adverse events ‐ not reported · patients with Shigella dysentery

The review found no eligible studies for this question.

1 finding from 1 review

Antibiotic therapy for Shigella dysentery 2010 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Sulphonamides vs tetracycline

Other adverse events ‐ not reported · patients with Shigella dysentery

The review found no eligible studies for this question.

1 finding from 1 review

Antibiotic therapy for Shigella dysentery 2010 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found