Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

331 questions · 336 findings · 74 reviews · Pregnancy and Childbirth · Headline outcomes only

No studies found 102 · 30.4%GRADE not reported 30 · 8.9%Very low 76 · 22.6%Low 92 · 27.4%Moderate 31 · 9.2%High 5 · 1.5%

Any antihypertensive drug vs no antihypertensive drugs/placebo

Admission to neonatal or intensive care nursery · women with mild to moderate hypertension during pregnancy

Any antihypertensive drug showed no clear difference in admission to neonatal or intensive care nursery compared with no antihypertensive drugs/placebo (low certainty).

1 finding from 1 review

TENS vs no TENS

Relief of pain · women who have given birth vaginally, requiring analgesia for after‐birth pains.

It is very uncertain whether TENS changes adequate pain relief as reported by the woman (during next breast… compared with no TENS (very low certainty).

1 finding from 1 review

TENS vs no TENS

Additional analgesia required (escape analgesia) · women who have given birth vaginally, requiring analgesia for after‐birth pains.

The review found no eligible studies for this question.

1 finding from 1 review

Any antihypertensive drug vs no antihypertensive drugs/placebo

Maternal · women with mild to moderate hypertension during pregnancy

The review found no eligible studies for this question.

2 findings from 1 review

Any antihypertensive drug vs no antihypertensive drugs/placebo

Changed/stopped drugs due to maternal side‐effects · women with mild to moderate hypertension during pregnancy

Any antihypertensive drug showed no clear difference in changed/stopped drugs due to maternal side‐effects compared with no antihypertensive drugs/placebo (low certainty).

1 finding from 1 review

Any antihypertensive drug vs no antihypertensive drugs/placebo

Elective delivery (induction of labour + elective caesarean section) · women with mild to moderate hypertension during pregnancy

Any antihypertensive drug showed no clear difference in elective delivery (induction of labour + elective caesarean section) compared with no antihypertensive drugs/placebo (moderate certainty).

1 finding from 1 review

Any antihypertensive drug vs no antihypertensive drugs/placebo

Fetal/neonatal/infant · women with mild to moderate hypertension during pregnancy

The review found no eligible studies for this question.

2 findings from 1 review

Any antihypertensive drug vs no antihypertensive drugs/placebo

Total reported fetal or neonatal deaths (including miscarriage) · women with mild to moderate hypertension during pregnancy

Any antihypertensive drug showed no clear difference in total reported fetal or neonatal deaths (including miscarriage) compared with no antihypertensive drugs/placebo (moderate certainty).

1 finding from 1 review

Any antihypertensive drug vs no antihypertensive drugs/placebo

Small‐for‐gestational age · women with mild to moderate hypertension during pregnancy

Any antihypertensive drug showed no clear difference in small‐for‐gestational age compared with no antihypertensive drugs/placebo (moderate certainty).

1 finding from 1 review