Caries distribution (individual/tooth/surface level) · European adolescents aged 12–19 years
Caries distribution was skewed at individual, tooth and surface levels and too heterogeneous to meta-analyze (narrative synthesis of 11 studies; not GRADE-rated).
1 finding from 1 review
No meta-analysis possible; caries distribution reported narratively from 11 studies as skewed at individual, tooth and surface levels, changing with age at tooth and surface level (Results – Caries distribution).
11 studies
GRADE not reported
Restoration survival · Children with decayed primary molar teeth
Multi-surface ART/HVGIC restorations had lower reported survival (49% at 3 years) than single-surface restorations (ungraded).
1 finding from 1 review
Survival rate (%) 49
9 studies
GRADE not reported
Restoration failure · Children (2-9 years) with caries in posterior primary teeth
Multi-surface ART restorations had a high reported mean annual failure rate (17%; ungraded).
1 finding from 1 review
Restoration failure · Children (2-9 years) with caries in posterior primary teeth
Single-surface ART restorations had a low reported mean annual failure rate (about 5%; ungraded).
1 finding from 1 review
Restoration survival · Children with decayed primary molar teeth
Single-surface ART/HVGIC restorations had high reported survival (86% at 3 years), significantly higher than multi-surface restorations (ungraded).
1 finding from 1 review
Survival rate (%) 86
9 studies
GRADE not reported
Treatment failure (annual failure rate) by cavity class · Children with carious primary teeth restored in Class-I versus Class-II cavities, no pulp therapy
Class-II restorations failed more than Class-I (annual failure 5-28.9% vs 1.2-14.7% in ART studies); low quality of evidence (ungraded).
1 finding from 1 review
Restoration failure · Children with carious primary teeth
No comparative effect estimate was reported; bilayer placement and nanofilled coating were described as improving survival.
1 finding from 1 review
Annual failure rate (%) 32.4%, 13.7%, 18.7%, 13.4% by insertion/coating arm
1 study · 208 participants
GRADE not reported
Restoration survival · Permanent posterior teeth with single-surface cavities
Single-surface high-viscosity glass-ionomer ART restorations in permanent teeth had high 2-year survival (93%, 95% CI 89-95%); evidence ungraded.
6 findings from 1 review
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Restoration survival · Primary posterior teeth with single-surface cavities
Single-surface high-viscosity glass-ionomer ART restorations in primary teeth had high 2-year survival (93%, 95% CI 91-94%); evidence ungraded.
3 findings from 1 review
Restoration survival · Primary posterior teeth with multiple-surface cavities
Multiple-surface high-viscosity glass-ionomer ART restorations in primary teeth had moderate 2-year survival (62%, 95% CI 51-73%); evidence ungraded.
3 findings from 1 review
Restoration survival · Permanent posterior teeth with multiple-surface cavities
Multiple-surface high-viscosity glass-ionomer ART restorations in permanent teeth had high 1-year survival (86%, 95% CI 59-98%); evidence ungraded.
3 findings from 1 review
DMFS (decayed, missing, filled surfaces) increment, occlusal surfaces · Schoolchildren aged 6-12 years with sound occlusal surfaces of the first permanent molars
Pit and fissure sealant and fluoride varnish showed no statistically significant difference in DMFS increment at 24 months (SMD -0.13, 95% CI -0.67 to 0.40; I2=92%; not GRADE-rated).
1 finding from 1 review
Arrest of advanced cavitated carious lesions on any coronal surface · Preschool children with advanced cavitated carious lesions on any coronal surface (primary teeth)
38% SDF solution (applied biannually) was more effective than 12% SDF solution (applied biannually) for arrest or reversal of cavitated coronal carious lesions (RR 1.3, 95% CI 1.21 to 1.41; high certainty).
4 findings from 1 review
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Arrest or reversal of noncavitated carious lesions on any coronal surface · Children and adults with noncavitated carious lesions on any coronal surface (primary and permanent teeth)
1.23% APF gel was probably more effective than 10% CPP-ACP paste for arrest or reversal of any-coronal carious lesions (RR 2.19, 95% CI 1.83 to 2.61; moderate certainty).
1 finding from 1 review
Arrest of advanced cavitated carious lesions on any coronal surface · Preschool children with advanced cavitated carious lesions on any coronal surface (primary teeth)
38% SDF solution (applied biannually) was more effective than 38% SDF solution (applied annually) for arrest or reversal of cavitated coronal carious lesions (RR 1.21, 95% CI 1.12 to 1.3; high certainty).
4 findings from 1 review
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Arrest of advanced cavitated carious lesions on any coronal surface · Preschool children with advanced cavitated carious lesions on any coronal surface (primary teeth)
30% SDF solution (applied annually) probably did not differ from 30% SDF solution (once weekly for 3 weeks) for arrest or reversal of cavitated coronal carious lesions (RR 1.13, 95% CI 0.95 to 1.34; moderate certainty).
3 findings from 1 review
Arrest of advanced cavitated carious lesions on any coronal surface · Preschool children with advanced cavitated carious lesions on any coronal surface (primary teeth)
30% SDF solution (applied annually) was more effective than 5% NaF varnish (once weekly for 3 weeks) for arrest or reversal of cavitated coronal carious lesions (RR 1.41, 95% CI 1.2 to 1.66; high certainty).
3 findings from 1 review
Arrest of advanced cavitated carious lesions on any coronal surface · Preschool children with advanced cavitated carious lesions on any coronal surface (primary teeth)
38% SDF solution (applied annually) was more effective than 12% SDF solution (applied annually) for arrest or reversal of cavitated coronal carious lesions (RR 1.27, 95% CI 1.16 to 1.4; high certainty).
4 findings from 1 review
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Arrest of advanced cavitated carious lesions on any coronal surface · Preschool children with advanced cavitated carious lesions on any coronal surface (primary teeth)
12% SDF solution (applied annually) did not differ from 12% SDF solution (applied biannually) for arrest or reversal of cavitated coronal carious lesions (RR 0.94, 95% CI 0.87 to 1.02; high certainty).
4 findings from 1 review
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Arrest or reversal of noncavitated carious lesions on any coronal surface · Children and adults with noncavitated carious lesions on any coronal surface (primary and permanent teeth)
1.23% APF gel was probably more effective than no treatment for arrest or reversal of any-coronal carious lesions (RR 2.25, 95% CI 2 to 2.53; moderate certainty).
1 finding from 1 review