What do systematic reviews say?

Immunoglobulin vs placebo

It is very uncertain whether summary of findings table ‐ Immunoglobulins changes mortality (any cause during hospitalisation or compared with placebo (very low certainty).

• Immunoglobulin treatment for hospitalised infants and young children with respiratory syncytial virus infection 2023 · Cochrane Headline outcomes only
  RR 0.87 [0.14, 5.27]
  4 studies · 309 participants
  Very low

Summary of findings table ‐ Enteral tube feeding vs intravenous fluids

• Parenteral versus enteral fluid therapy for children hospitalised with bronchiolitis 2021 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 810 participants
  Moderate

Vitamin A vs placebo

Summary of findings table ‐ Vitamin A supplements showed no clear difference in incidence of acute URTIs during the study period (the number of… compared with placebo (low certainty).

• Oral vitamin A supplements to prevent acute upper respiratory tract infections in children up to seven years of age 2024 · Cochrane Headline outcomes only
  RR 1 [0.92, 1.09]
  3 studies · 22668 participants
  Low

Vitamin A vs placebo

• Oral vitamin A supplements to prevent acute upper respiratory tract infections in children up to seven years of age 2024 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 15535 participants
  Low