Findings

What do systematic reviews say?

10 questions · 10 findings · 2 reviews

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No studies found 4 · 40%GRADE not reported 0 · 0%Very low 1 · 10%Low 5 · 50%Moderate 0 · 0%High 0 · 0%

Closest answers

The findings closest to your search, judged one by one by TypeSafe's Jev model.

Direct match · question page
- Streptokinase vs urokinase · Overall treatment failure, including mortality, thoracic surgery or referral for further fibrinolytic therapy
  Intra‐pleural fibrinolytic therapy versus placebo, or a different fibrinolytic agent, in the treatment of adult… 2019 · Cochrane Headline outcomes only
  OR 1 [0.13, 7.72]
  1 study · 50 participants
  Low
Direct match · question page
- Streptokinase/streptodornase (enzymatic) vs saline‐soaked dressing · Proportion of wounds completely healed
  Debridement for surgical wounds 2024 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found
Direct match · question page
- Streptokinase/streptodornase (enzymatic) vs saline‐soaked dressing · Time to a clean wound bed (
  Debridement for surgical wounds 2024 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 21 participants
  Low
Direct match · question page
- Streptokinase/streptodornase (enzymatic) vs saline‐soaked dressing · Proportion of wounds completely debrided
  Debridement for surgical wounds 2024 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found
Direct match · question page
- Streptokinase/streptodornase (enzymatic) vs saline‐soaked dressing · Time to complete healing (days)
  Debridement for surgical wounds 2024 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Streptokinase vs urokinase

All‐cause mortality · adult parapneumonic effusions and empyema

Streptokinase showed no clear difference in mortality compared with urokinase (low certainty).

1 finding from 1 review

Intra‐pleural fibrinolytic therapy versus placebo, or a different fibrinolytic agent, in the treatment of adult… 2019 · Cochrane Headline outcomes only
OR 0.32 [0.01, 8.25]
1 study · 50 participants
Low

Streptokinase vs urokinase

Referral for thoracic surgery (open or thorascopic) · adult parapneumonic effusions and empyema

Streptokinase showed no clear difference in referral for thoracic surgery (open or thorascopic) compared with urokinase (low certainty).

1 finding from 1 review

Intra‐pleural fibrinolytic therapy versus placebo, or a different fibrinolytic agent, in the treatment of adult… 2019 · Cochrane Headline outcomes only
OR 1 [0.13, 7.72]
1 study · 50 participants
Low

Streptokinase vs urokinase

Overall treatment failure, including mortality, thoracic surgery or referral for further fibrinolytic therapy · adult parapneumonic effusions and empyema

Streptokinase showed no clear difference in overall treatment failure, including mortality, thoracic surgery or… compared with urokinase (low certainty).

1 finding from 1 review

Intra‐pleural fibrinolytic therapy versus placebo, or a different fibrinolytic agent, in the treatment of adult… 2019 · Cochrane Headline outcomes only
OR 1 [0.13, 7.72]
1 study · 50 participants
Low

Streptokinase vs urokinase

Serious adverse events · adult parapneumonic effusions and empyema

Streptokinase showed no clear difference in serious adverse events compared with urokinase (low certainty).

1 finding from 1 review

Intra‐pleural fibrinolytic therapy versus placebo, or a different fibrinolytic agent, in the treatment of adult… 2019 · Cochrane Headline outcomes only
OR 5.43 [0.25, 118.96]
1 study · 50 participants
Low

Streptokinase/streptodornase (enzymatic) vs saline dressing

Time to a clean wound bed ( · adults with surgical wounds

Streptokinase/streptodornase (enzymatic) may leads to lower time to a clean wound bed ( compared with saline‐soaked dressing (low certainty).

1 finding from 1 review

Debridement for surgical wounds 2024 · Cochrane Headline outcomes only
no estimate extracted
1 study · 21 participants
Low

Streptokinase/streptodornase (enzymatic) vs saline dressing

Proportion of wounds completely debrided · adults with surgical wounds

The review found no eligible studies for this question.

1 finding from 1 review

Debridement for surgical wounds 2024 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Streptokinase/streptodornase (enzymatic) vs saline dressing

Rate of reduction in wound size · adults with surgical wounds

The review found no eligible studies for this question.

1 finding from 1 review

Debridement for surgical wounds 2024 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Streptokinase/streptodornase (enzymatic) vs saline dressing

Proportion of wounds healed · adults with surgical wounds

The review found no eligible studies for this question.

1 finding from 1 review

Debridement for surgical wounds 2024 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Streptokinase/streptodornase (enzymatic) vs saline dressing

Time to complete healing · adults with surgical wounds

The review found no eligible studies for this question.

1 finding from 1 review

Debridement for surgical wounds 2024 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Streptokinase/streptodornase (enzymatic) vs saline dressing

Serious adverse events: life‐threatening/ hospitalisation · adults with surgical wounds

1 finding from 1 review

Debridement for surgical wounds 2024 · Cochrane Headline outcomes only
no estimate extracted
1 study · 21 participants
Very low