Findings

What do systematic reviews say?

15 questions · 15 findings · 3 reviews · Oral and maxillofacial surgery · All outcomes

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No studies found 10 · 66.7%GRADE not reported 5 · 33.3%Very low 0 · 0%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Iontophoretically applied corticosteroids

Outcome not reported · Adults (>18 years) with temporomandibular joint osteoarthritis (TMJ OA) diagnosed by RDC/TMD or compatible criteria

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for managing temporomandibular joint osteoarthritis 2012 · Cochrane All outcomes
The review noted the noticeable absence of evidence for iontophoretically applied corticosteroids; no eligible RCT evaluated it (Discussion).
0 studies
No studies found

Medical interventions (systemic: analgesics, antidepressants, antiepileptics, steroids; topical: analgesics, anaesthetics) vs Another intervention, or no intervention

Outcome not reported · Patients of any age in any setting requiring intervention for iatrogenic injury to the inferior alveolar or lingual nerve

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for iatrogenic inferior alveolar and lingual nerve injury 2014 · Cochrane All outcomes
Results: 'No studies evaluated medical ... interventions.' No eligible RCT of medical interventions (analgesics, antidepressants, antiepileptics, steroids, topical anaesthetics).
0 studies
No studies found

Intra-articular injection of sodium hyaluronate vs corticosteroid injection

Complications (adverse effects) · Adults (>18 years) with temporomandibular joint osteoarthritis (TMJ OA) diagnosed by RDC/TMD or compatible criteria

Intra-articular injection of sodium hyaluronate showed no clear difference in complications (adverse effects) compared with intra-articular injection of corticosteroids (betamethasone); GRADE not reported.

1 finding from 1 review

Interventions for managing temporomandibular joint osteoarthritis 2012 · Cochrane All outcomes
RR 1.20 [0.44, 3.30]
1 study · 40 participants
GRADE not reported

Intra-articular injection of sodium hyaluronate vs corticosteroid injection

Presence of TMJ sounds · Adults (>18 years) with temporomandibular joint osteoarthritis (TMJ OA) diagnosed by RDC/TMD or compatible criteria

Intra-articular injection of sodium hyaluronate led to lower presence of TMJ sounds compared with intra-articular injection of corticosteroids (betamethasone); GRADE not reported.

1 finding from 1 review

Interventions for managing temporomandibular joint osteoarthritis 2012 · Cochrane All outcomes
14 days
RR 0.59 [0.37, 0.95]
1 study · 40 participants
GRADE not reported

Intra-articular injection of sodium hyaluronate vs corticosteroid injection

Pain on palpation of the affected/contralateral TMJ and masticatory muscles · Adults (>18 years) with temporomandibular joint osteoarthritis (TMJ OA) diagnosed by RDC/TMD or compatible criteria

Intra-articular injection of sodium hyaluronate led to lower pain on palpation of the affected/contralateral TMJ and masticatory… compared with intra-articular injection of corticosteroids (betamethasone); GRADE not reported.

1 finding from 1 review

Interventions for managing temporomandibular joint osteoarthritis 2012 · Cochrane All outcomes
14 days to 6 months
Pain on palpation of the affected and contralateral TMJ and masticatory muscles presented similar frequencies regardless of the time (Analyses 1.4-1.12); no statistically significant differences reported. Point…
1 study · 40 participants
GRADE not reported

Intra-articular injection of sodium hyaluronate vs corticosteroid injection

Extent of mandibular movement (maximum jaw opening, lateral and contralateral movement, jaw protrusion) · Adults (>18 years) with temporomandibular joint osteoarthritis (TMJ OA) diagnosed by RDC/TMD or compatible criteria

Intra-articular injection of sodium hyaluronate showed no clear difference in extent of mandibular movement (maximum jaw opening, lateral and… compared with intra-articular injection of corticosteroids (betamethasone); GRADE not reported.

1 finding from 1 review

Interventions for managing temporomandibular joint osteoarthritis 2012 · Cochrane All outcomes
14 days to 6 months
None of the mean differences between interventions for the measures of jaw movements (maximum jaw opening, lateral movement to affected side, contralateral movement, jaw protrusion; Analyses 1.16-1.27) showed…
1 study · 40 participants
GRADE not reported

Intra-articular injection of sodium hyaluronate vs corticosteroid injection

Reported pain (mm on VAS) · Adults (>18 years) with temporomandibular joint osteoarthritis (TMJ OA) diagnosed by RDC/TMD or compatible criteria

Intra-articular injection of sodium hyaluronate led to lower reported pain (mm on VAS) compared with intra-articular injection of corticosteroids (betamethasone); GRADE not reported.

1 finding from 1 review

Interventions for managing temporomandibular joint osteoarthritis 2012 · Cochrane All outcomes
6 months
MD -17.00 [-32.60, -1.40]
1 study · 40 participants
GRADE not reported

Primary surgical intervention (curettage, peripheral osteotomy, or resection) vs Primary non-surgical intervention (intralesional corticosteroids, subcutaneous calcitonin, interferon alpha, or imatinib)

Overall survival · Patients with a pathological diagnosis of central giant cell granuloma (CGCG) of the jaws

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for central giant cell granuloma (CGCG) of the jaws 2009 · Cochrane All outcomes
no estimate extracted
0 studies
No studies found

Primary surgical intervention (curettage, peripheral osteotomy, or resection) vs Primary non-surgical intervention (intralesional corticosteroids, subcutaneous calcitonin, interferon alpha, or imatinib)

Disease-free survival · Patients with a pathological diagnosis of central giant cell granuloma (CGCG) of the jaws

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for central giant cell granuloma (CGCG) of the jaws 2009 · Cochrane All outcomes
no estimate extracted
0 studies
No studies found

Primary surgical intervention (curettage, peripheral osteotomy, or resection) vs Primary non-surgical intervention (intralesional corticosteroids, subcutaneous calcitonin, interferon alpha, or imatinib)

Resectability · Patients with a pathological diagnosis of central giant cell granuloma (CGCG) of the jaws

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for central giant cell granuloma (CGCG) of the jaws 2009 · Cochrane All outcomes
no estimate extracted
0 studies
No studies found

Primary surgical intervention (curettage, peripheral osteotomy, or resection) vs Primary non-surgical intervention (intralesional corticosteroids, subcutaneous calcitonin, interferon alpha, or imatinib)

Quality of life · Patients with a pathological diagnosis of central giant cell granuloma (CGCG) of the jaws

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for central giant cell granuloma (CGCG) of the jaws 2009 · Cochrane All outcomes
no estimate extracted
0 studies
No studies found

Primary surgical intervention (curettage, peripheral osteotomy, or resection) vs Primary non-surgical intervention (intralesional corticosteroids, subcutaneous calcitonin, interferon alpha, or imatinib)

Adverse events · Patients with a pathological diagnosis of central giant cell granuloma (CGCG) of the jaws

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for central giant cell granuloma (CGCG) of the jaws 2009 · Cochrane All outcomes
no estimate extracted
0 studies
No studies found

Primary surgical intervention (curettage, peripheral osteotomy, or resection) vs Primary non-surgical intervention (intralesional corticosteroids, subcutaneous calcitonin, interferon alpha, or imatinib)

Complete remission · Patients with a pathological diagnosis of central giant cell granuloma (CGCG) of the jaws

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for central giant cell granuloma (CGCG) of the jaws 2009 · Cochrane All outcomes
no estimate extracted
0 studies
No studies found

Primary surgical intervention (curettage, peripheral osteotomy, or resection) vs Primary non-surgical intervention (intralesional corticosteroids, subcutaneous calcitonin, interferon alpha, or imatinib)

Partial reduction · Patients with a pathological diagnosis of central giant cell granuloma (CGCG) of the jaws

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for central giant cell granuloma (CGCG) of the jaws 2009 · Cochrane All outcomes
no estimate extracted
0 studies
No studies found

Primary surgical intervention (curettage, peripheral osteotomy, or resection) vs Primary non-surgical intervention (intralesional corticosteroids, subcutaneous calcitonin, interferon alpha, or imatinib)

Recurrence · Patients with a pathological diagnosis of central giant cell granuloma (CGCG) of the jaws

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for central giant cell granuloma (CGCG) of the jaws 2009 · Cochrane All outcomes
no estimate extracted
0 studies
No studies found