Maternal mortality due to bleeding · women with primary postpartum haemorrhage following vaginal or caesarean birth
Standard care plus IV tranexamic acid showed no clear difference in maternal mortality due to bleeding compared with placebo or standard care alone (moderate certainty).
1 finding from 1 review
Maternal mortality ‐ not reported · women with primary postpartum haemorrhage following vaginal or caesarean birth
Standard care plus IV tranexamic acid showed no clear difference in maternal mortality (all causes) compared with placebo or standard care alone (moderate certainty).
1 finding from 1 review
Serious maternal morbidity · women with primary postpartum haemorrhage following vaginal or caesarean birth
Standard care plus IV tranexamic acid showed no clear difference in serious maternal morbidity (any) compared with placebo or standard care alone (high certainty).
1 finding from 1 review
Maternal blood loss of 500 mL or greater · women with primary postpartum haemorrhage following vaginal or caesarean birth
Standard care plus IV tranexamic acid may leads to lower blood loss 500 mL or more after randomisation compared with placebo or standard care alone (low certainty).
1 finding from 1 review
Blood transfusion · women with primary postpartum haemorrhage following vaginal or caesarean birth
Standard care plus IV tranexamic acid showed no clear difference in blood transfusion (any) compared with placebo or standard care alone (moderate certainty).
1 finding from 1 review
Hysterectomy to control bleeding · women with primary postpartum haemorrhage following vaginal or caesarean birth
Standard care plus IV tranexamic acid showed no clear difference in surgical intervention to control bleeding: Hysterectomy compared with placebo or standard care alone (high certainty).
1 finding from 1 review
Side effects of the intervention: Any maternal vascular occlusive event · women with primary postpartum haemorrhage following vaginal or caesarean birth
Standard care plus IV tranexamic acid showed no clear difference in side effects of the intervention: Any maternal vascular occlusive… compared with placebo or standard care alone (moderate certainty).
1 finding from 1 review