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What do systematic reviews say?

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Evidence found and GRADE certainty

2 questions · 2 findings · 1 reviews

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No studies found 0 · 0%GRADE not reported 0 · 0%Very low 1 · 50%Low 1 · 50%Moderate 0 · 0%High 0 · 0%

Simethicone vs placebo

Reduction in crying duration Difference between final values (hours per day of crying) · infants with colic defined by recognised criteria

It is very uncertain whether simethicone changes reduction in crying duration Difference between final values (hours… compared with placebo (very low certainty).

1 finding from 1 review

Simethicone vs placebo

Responders Number of infants who improved after treatment · infants with colic defined by recognised criteria

Simethicone showed no clear difference in responders Number of infants who improved after treatment compared with placebo (low certainty).

1 finding from 1 review