Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

18 questions · 18 findings · 2 reviews · Acute Respiratory Infections

No studies found 0 · 0%GRADE not reported 11 · 61.1%Very low 0 · 0%Low 3 · 16.7%Moderate 4 · 22.2%High 0 · 0%

Antibiotics (short duration) vs prolonged‐course antibiotic therapy be used

All‐cause mortality · hospital‐acquired pneumonia

Should short‐course antibiotic therapy showed no clear difference in mortality compared with prolonged‐course antibiotic therapy be used (moderate certainty).

1 finding from 1 review

Antibiotics (short duration) vs prolonged‐course antibiotic therapy be used

Mortality NF‐GNB · hospital‐acquired pneumonia

Should short‐course antibiotic therapy showed no clear difference in mortality NF‐GNB compared with prolonged‐course antibiotic therapy be used (low certainty).

1 finding from 1 review

Antibiotics (short duration) vs prolonged‐course antibiotic therapy be used

Mortality MRSA · hospital‐acquired pneumonia

Should short‐course antibiotic therapy showed no clear difference in mortality MRSA compared with prolonged‐course antibiotic therapy be used (moderate certainty).

1 finding from 1 review

Antibiotics (short duration) vs prolonged‐course antibiotic therapy be used

Recurrence of pneumonia · hospital‐acquired pneumonia

Should short‐course antibiotic therapy showed no clear difference in recurrence of pneumonia Clinical and/or microbiological criteria compared with prolonged‐course antibiotic therapy be used (low certainty).

1 finding from 1 review

Antibiotics (short duration) vs prolonged‐course antibiotic therapy be used

Recurrence of pneumonia ‐ NF‐GNB · hospital‐acquired pneumonia

Should short‐course antibiotic therapy probably leads to higher recurrence of pneumonia NF‐GNB Clinical and/or microbiological… compared with prolonged‐course antibiotic therapy be used (moderate certainty).

1 finding from 1 review

Antibiotics (short duration) vs prolonged‐course antibiotic therapy be used

Recurrence of pneumonia ‐ MRSA · hospital‐acquired pneumonia

Should short‐course antibiotic therapy showed no clear difference in recurrence of pneumonia MRSA Clinical and/or microbiological criteria compared with prolonged‐course antibiotic therapy be used (moderate certainty).

1 finding from 1 review

Intervention not reported

Treatment failure at 1 month or less · patients with acute otitis media

The intervention led to higher treatment failure at 1 month or less; GRADE not reported.

1 finding from 1 review

Intervention not reported

Treatment failure at 8 to 19 days · patients with acute otitis media

The intervention led to higher treatment failure at 8 to 19 days; GRADE not reported.

1 finding from 1 review

Intervention not reported

Treatment failure at 20 to 30 days · patients with acute otitis media

The intervention showed no clear difference in treatment failure at 20 to 30 days; GRADE not reported.

1 finding from 1 review

Intervention not reported

Treatment failure at 8 to 19 days · patients with acute otitis media

The intervention led to higher treatment failure at 8 to 19 days; GRADE not reported.

1 finding from 1 review

Intervention not reported

Treatment failure at 20 to 30 days · patients with acute otitis media

The intervention showed no clear difference in treatment failure at 20 to 30 days; GRADE not reported.

1 finding from 1 review

Intervention not reported

Treatment failure at 3 months or less · patients with acute otitis media

The intervention showed no clear difference in treatment failure at 3 months or less; GRADE not reported.

1 finding from 1 review

Intervention not reported

Treatment failure at 90 days · patients with acute otitis media

The intervention showed no clear difference in treatment failure at 90 days; GRADE not reported.

1 finding from 1 review

Intervention not reported

Treatment failure at 30 to 45 days · patients with acute otitis media

The intervention showed no clear difference in treatment failure at 30 to 45 days; GRADE not reported.

1 finding from 1 review

Intervention not reported

Treatment failure at 1 month or less · patients with acute otitis media

The intervention showed no clear difference in treatment failure at 1 month or less; GRADE not reported.

1 finding from 1 review

Intervention not reported

Treatment failure at 3 months or less · patients with acute otitis media

The intervention showed no clear difference in treatment failure at 3 months or less; GRADE not reported.

1 finding from 1 review

Intervention not reported

Treatment failure at 1 month or less · patients with acute otitis media

The intervention showed no clear difference in treatment failure at 1 month or less; GRADE not reported.

1 finding from 1 review