Findings

What do systematic reviews say?

41 questions · 41 findings · 5 reviews

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No studies found 0 · 0%GRADE not reported 5 · 12.2%Very low 8 · 19.5%Low 10 · 24.4%Moderate 18 · 43.9%High 0 · 0%

Sertraline vs cognitive behavioural therapy

> 50% reduction in depressive symptoms · people with epilepsy and depression

1 finding from 1 review

Antidepressants for people with epilepsy and depression 2021 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported

Sertraline vs cognitive behavioural therapy

Depressive symptoms · people with epilepsy and depression

1 finding from 1 review

Antidepressants for people with epilepsy and depression 2021 · Cochrane Headline outcomes only
no estimate extracted
1 study · 117 participants
Moderate

Sertraline vs cognitive behavioural therapy

Seizure frequency · people with epilepsy and depression

1 finding from 1 review

Antidepressants for people with epilepsy and depression 2021 · Cochrane Headline outcomes only
no estimate extracted
1 study · 96 participants
Low

Sertraline vs cognitive behavioural therapy

Treatment withdrawal · people with epilepsy and depression

Sertraline showed no clear difference in withdrawals compared with cognitive behavioural therapy (moderate certainty).

1 finding from 1 review

Antidepressants for people with epilepsy and depression 2021 · Cochrane Headline outcomes only
RR 1.26 [0.64, 2.46]
1 study · 140 participants
Moderate

Sertraline vs cognitive behavioural therapy

Cognitive function · people with epilepsy and depression

1 finding from 1 review

Antidepressants for people with epilepsy and depression 2021 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported

Sertraline vs cognitive behavioural therapy

Quality of life (QOLIE‐89) (1‐ to 3‐month periods) · people with epilepsy and depression

1 finding from 1 review

Antidepressants for people with epilepsy and depression 2021 · Cochrane Headline outcomes only
no estimate extracted
1 study · 118 participants
Moderate

Sertraline vs cognitive behavioural therapy

Adverse effects · people with epilepsy and depression

1 finding from 1 review

Antidepressants for people with epilepsy and depression 2021 · Cochrane Headline outcomes only
no estimate extracted
1 study · 118 participants
Low

Intervention not reported

paroxetine:sertraline · children and/or adolescents with depression

1 finding from 1 review

New generation antidepressants for depression in children and adolescents: a network meta‐analysis 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Low

Intervention not reported

sertraline:venlafaxine · children and/or adolescents with depression

1 finding from 1 review

New generation antidepressants for depression in children and adolescents: a network meta‐analysis 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Very low

Intervention not reported

vilazodone:sertraline · children and/or adolescents with depression

1 finding from 1 review

New generation antidepressants for depression in children and adolescents: a network meta‐analysis 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Very low

Intervention not reported

vortioxetine:sertraline · children and/or adolescents with depression

1 finding from 1 review

New generation antidepressants for depression in children and adolescents: a network meta‐analysis 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Very low

Intervention not reported

sertraline:citalopram · children and/or adolescents with depression

1 finding from 1 review

New generation antidepressants for depression in children and adolescents: a network meta‐analysis 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Very low

Intervention not reported

sertraline:placebo · children and/or adolescents with depression

1 finding from 1 review

New generation antidepressants for depression in children and adolescents: a network meta‐analysis 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Low

Intervention not reported

sertraline:desvenlafaxine · children and/or adolescents with depression

1 finding from 1 review

New generation antidepressants for depression in children and adolescents: a network meta‐analysis 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Moderate

Intervention not reported

sertraline:duloxetine · children and/or adolescents with depression

1 finding from 1 review

New generation antidepressants for depression in children and adolescents: a network meta‐analysis 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Moderate

Intervention not reported

sertraline:escitalopram · children and/or adolescents with depression

1 finding from 1 review

New generation antidepressants for depression in children and adolescents: a network meta‐analysis 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Moderate

Intervention not reported

sertraline:fluoxetine · children and/or adolescents with depression

1 finding from 1 review

New generation antidepressants for depression in children and adolescents: a network meta‐analysis 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Moderate

Intervention not reported

sertraline:mirtazapine · children and/or adolescents with depression

1 finding from 1 review

New generation antidepressants for depression in children and adolescents: a network meta‐analysis 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Very low

Intervention not reported

sertraline:paroxetine · children and/or adolescents with depression

1 finding from 1 review

New generation antidepressants for depression in children and adolescents: a network meta‐analysis 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Moderate

Intervention not reported

sertraline:venlafaxine · children and/or adolescents with depression

1 finding from 1 review

New generation antidepressants for depression in children and adolescents: a network meta‐analysis 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Low