Findings

What do systematic reviews say?

13 questions · 13 findings · 1 reviews · Lung Cancer

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No studies found 3 · 23.1%GRADE not reported 0 · 0%Very low 0 · 0%Low 0 · 0%Moderate 0 · 0%High 10 · 76.9%

Selenium vs placebo

Incidence: lung cancer · healthy men

Selenium showed no clear difference in incidence: lung cancer compared with placebo (high certainty).

1 finding from 1 review

Drugs for preventing lung cancer in healthy people 2020 · Cochrane Headline outcomes only
RR 1.11 [0.8, 1.54]
1 study · 17448 participants
High

Selenium vs placebo

Mortality: lung cancer · healthy men

1 finding from 1 review

Drugs for preventing lung cancer in healthy people 2020 · Cochrane Headline outcomes only
1.09 [0.72, 1.66]
1 study · 17448 participants
High

Selenium vs placebo

Alopecia · healthy men

Selenium leads to higher adverse events: alopecia compared with placebo (high certainty).

1 finding from 1 review

Drugs for preventing lung cancer in healthy people 2020 · Cochrane Headline outcomes only
RR 1.28 [1.07, 1.53]
1 study · 17448 participants
High

Selenium vs placebo

adverse events: grade 1 to 2 dermatitis · healthy men

Selenium leads to higher adverse events: grade 1 to 2 dermatitis compared with placebo (high certainty).

1 finding from 1 review

Drugs for preventing lung cancer in healthy people 2020 · Cochrane Headline outcomes only
RR 1.16 [1.04, 1.31]
1 study · 17448 participants
High

Selenium vs placebo

Incidence: all cancers · healthy men

Selenium showed no clear difference in incidence: all cancers compared with placebo (high certainty).

1 finding from 1 review

Drugs for preventing lung cancer in healthy people 2020 · Cochrane Headline outcomes only
RR 1.01 [0.92, 1.11]
1 study · 17448 participants
High

Selenium vs placebo

Mortality: all cancers · healthy men

Selenium showed no clear difference in mortality: all cancers compared with placebo (high certainty).

1 finding from 1 review

Drugs for preventing lung cancer in healthy people 2020 · Cochrane Headline outcomes only
RR 1.02 [0.8, 1.3]
1 study · 17448 participants
High

Selenium vs placebo

Mortality: all causes · healthy men

Selenium showed no clear difference in mortality: all causes compared with placebo (high certainty).

1 finding from 1 review

Drugs for preventing lung cancer in healthy people 2020 · Cochrane Headline outcomes only
RR 0.98 [0.86, 1.13]
1 study · 17448 participants
High

Vitamins A, C, E + selenium + zinc vs placebo

Incidence: lung cancer · healthy women, aged 35 to 60, and men, aged 45 to 60, living in France

Vitamins A, C, E + selenium + zinc showed no clear difference in incidence: lung cancer compared with placebo (high certainty).

1 finding from 1 review

Drugs for preventing lung cancer in healthy people 2020 · Cochrane Headline outcomes only
RR 0.64 [0.28, 1.48]
1 study · 12741 participants
High

Vitamins A, C, E + selenium + zinc vs placebo

Mortality: lung cancer · healthy women, aged 35 to 60, and men, aged 45 to 60, living in France

The review found no eligible studies for this question.

1 finding from 1 review

Drugs for preventing lung cancer in healthy people 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Vitamins A, C, E + selenium + zinc vs placebo

Adverse events · healthy women, aged 35 to 60, and men, aged 45 to 60, living in France

The review found no eligible studies for this question.

1 finding from 1 review

Drugs for preventing lung cancer in healthy people 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Vitamins A, C, E + selenium + zinc vs placebo

Incidence: all cancers · healthy women, aged 35 to 60, and men, aged 45 to 60, living in France

Vitamins A, C, E + selenium + zinc showed no clear difference in incidence: all cancers compared with placebo (high certainty).

1 finding from 1 review

Drugs for preventing lung cancer in healthy people 2020 · Cochrane Headline outcomes only
RR 0.96 [0.83, 1.1]
1 study · 12741 participants
High

Vitamins A, C, E + selenium + zinc vs placebo

Mortality: all cancers · healthy women, aged 35 to 60, and men, aged 45 to 60, living in France

The review found no eligible studies for this question.

1 finding from 1 review

Drugs for preventing lung cancer in healthy people 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Vitamins A, C, E + selenium + zinc vs placebo

Mortality: all causes · healthy women, aged 35 to 60, and men, aged 45 to 60, living in France

Vitamins A, C, E + selenium + zinc showed no clear difference in mortality: all causes compared with placebo (high certainty).

1 finding from 1 review

Drugs for preventing lung cancer in healthy people 2020 · Cochrane Headline outcomes only
RR 0.88 [0.7, 1.11]
1 study · 12741 participants
High