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Evidence found and GRADE certainty

73 questions · 76 findings · 12 reviews · Common Mental Disorders

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No studies found 7 · 9.2%GRADE not reported 4 · 5.3%Very low 29 · 38.2%Low 25 · 32.9%Moderate 10 · 13.2%High 1 · 1.3%

Pharmacological interventions vs placebo

Incidence of depression ‐ short‐term: < 6 months · adults with long‐term physical conditions (18 years or older)

It is very uncertain whether pharmacological interventions changes incidence of depression ‐ short‐term: < 6 months compared with placebo (very low certainty).

1 finding from 1 review

Psychological interventions vs treatment

Incidence of depression ‐ short term: < 6 months · adults with long‐term physical conditions (18 years or older)

It is very uncertain whether psychological interventions changes incidence of depression ‐ short term: < 6 months compared with treatment (very low certainty).

1 finding from 1 review

Intervention not reported

MST vs ECT ‐ cognitive function ‐ immediate memory (high = better; short term) · patients with schizophrenia
1 finding from 1 review

Intervention not reported

MST vs ECT ‐ cognitive function ‐ delayed memory (high = better; short term) · patients with schizophrenia
1 finding from 1 review

Intervention not reported

MST vs ECT ‐ dropout for any reason (short term) · patients with schizophrenia

It is very uncertain whether the intervention changes MST vs ECT ‐ dropout for any reason (short term) (very low certainty).

1 finding from 1 review

Intervention not reported

MST vs ECT ‐ adverse events that led to discontinuation of treatment (short term) · patients with schizophrenia
1 finding from 1 review

Lamotrigine vs placebo

Any reported adverse effects up to 12 weeks after starting treatment (short term) · bipolar disorder

It is very uncertain whether lamotrigine changes any reported adverse effects up to 12 weeks after starting treatment… compared with placebo (very low certainty).

1 finding from 1 review

Intervention not reported

Depression score Scales: Beck Depression Inventory, Center for Epidemiologic Studies Short Depression Scale, Patient Health Questionnaire Direction: lower better · women aged 16 years and older who self‐report previous or current experience of intimate partner violence
1 finding from 1 review

Behavioural activation vs any comparator

Treatment efficacy for depression (short term: 8–9 weeks) · depression in adults with non‐communicable diseases

Behavioural activation showed no clear difference in treatment efficacy for depression (short term: 8–9 weeks) compared with any comparator (low certainty).

1 finding from 1 review