What do systematic reviews say?

Restricted vs standard fluid management

• Fluid restriction in the management of transient tachypnea of the newborn 2021 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 172 participants
  Very low

Restricted vs standard fluid management

It is very uncertain whether restricted changes incidence of hypernatremia (serum sodium > 145 mEq/L) at end of… compared with standard fluid management (very low certainty).

• Fluid restriction in the management of transient tachypnea of the newborn 2021 · Cochrane Headline outcomes only
  RR 4 [0.46, 34.54]
  1 study · 100 participants
  Very low

Restricted vs standard fluid management

It is very uncertain whether restricted changes incidence of hypoglycemia (blood glucose < 40 mg/dL) at end of… compared with standard fluid management (very low certainty).

• Fluid restriction in the management of transient tachypnea of the newborn 2021 · Cochrane Headline outcomes only
  RR 1 [0.15, 6.82]
  2 studies · 164 participants
  Very low

Restricted vs standard fluid management

It is very uncertain whether restricted changes incidence of endotracheal ventilation (proportions) during hospital… compared with standard fluid management (very low certainty).

• Fluid restriction in the management of transient tachypnea of the newborn 2021 · Cochrane Headline outcomes only
  RR 0.73 [0.24, 2.23]
  3 studies · 242 participants
  Very low

Restricted vs standard fluid management

It is very uncertain whether restricted changes incidence of noninvasive (nasal CPAP or nasal ventilation)… compared with standard fluid management (very low certainty).

• Fluid restriction in the management of transient tachypnea of the newborn 2021 · Cochrane Headline outcomes only
  RR 0.4 [0.14, 1.17]
  2 studies · 150 participants
  Very low

Restricted vs standard fluid management

• Fluid restriction in the management of transient tachypnea of the newborn 2021 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 80 participants
  Very low

Restricted vs standard fluid management

• Fluid restriction in the management of transient tachypnea of the newborn 2021 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 156 participants
  Very low

Fluid restricted vs liberal fluids compared to placebo

• Fluid restriction for treatment of preterm infants with chronic lung disease 2017 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 60 participants
  Low

Fluid restricted vs liberal fluids compared to placebo

• Fluid restriction for treatment of preterm infants with chronic lung disease 2017 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 60 participants
  Low

Fluid restricted vs liberal fluids compared to placebo

• Fluid restriction for treatment of preterm infants with chronic lung disease 2017 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 60 participants
  Low

Fluid restricted vs liberal fluids compared to placebo

Fluid restricted showed no clear difference in proportion with apnoea compared with liberal fluids compared to placebo (low certainty).

• Fluid restriction for treatment of preterm infants with chronic lung disease 2017 · Cochrane Headline outcomes only
  RR 1.35 [0.98, 1.86]
  1 study · 60 participants
  Low

High protein vs low protein intake (restricted to studies meeting all a priori inclusion criteria)

• Higher versus lower protein intake in formula‐fed low birth weight infants 2020 · Cochrane Headline outcomes only
  no estimate extracted
  5 studies · 114 participants
  Low

Very high protein vs low protein intake (restricted to studies meeting all a priori inclusion criteria)

The review found no eligible studies for this question.

• Higher versus lower protein intake in formula‐fed low birth weight infants 2020 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Very high protein vs high protein intake (restricted to studies meeting all a priori inclusion criteria)

• Higher versus lower protein intake in formula‐fed low birth weight infants 2020 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 77 participants
  Moderate

Very high protein vs high protein intake (restricted to studies meeting all a priori inclusion criteria)

• Higher versus lower protein intake in formula‐fed low birth weight infants 2020 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 77 participants
  Moderate

Very high protein vs high protein intake (restricted to studies meeting all a priori inclusion criteria)

The review found no eligible studies for this question.

• Higher versus lower protein intake in formula‐fed low birth weight infants 2020 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Very high protein vs high protein intake (restricted to studies meeting all a priori inclusion criteria)

The review found no eligible studies for this question.

• Higher versus lower protein intake in formula‐fed low birth weight infants 2020 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Very high protein vs high protein intake (restricted to studies meeting all a priori inclusion criteria)

The review found no eligible studies for this question.

• Higher versus lower protein intake in formula‐fed low birth weight infants 2020 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

High protein vs low protein intake (restricted to studies meeting all a priori inclusion criteria)

• Higher versus lower protein intake in formula‐fed low birth weight infants 2020 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 48 participants
  Low

High protein vs low protein intake (restricted to studies meeting all a priori inclusion criteria)

• Higher versus lower protein intake in formula‐fed low birth weight infants 2020 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 18 participants
  Very low