Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

37 questions · 37 findings · 4 reviews · Neonatal

No studies found 5 · 13.5%GRADE not reported 2 · 5.4%Very low 6 · 16.2%Low 22 · 59.5%Moderate 2 · 5.4%High 0 · 0%

Probiotics vs placebo

Proven sepsis (positive bacterial culture, local or systemic) · neonates born from 35 weeks of gestation who have underdone gastrointestinal surgery

Summary of findings table ‐ Probiotics showed no clear difference in proven sepsis (positive bacterial culture, local or systemic) compared with placebo (low certainty).

1 finding from 1 review

Probiotics administered to pregnant women at risk of preterm birth vs placebo or no intervention

Gestational age (preterm birth < 37 weeks) · preterm infants

Probiotics administered to pregnant women at risk of preterm birth showed no clear difference in preterm birth < 37 weeks' gestation compared with placebo or no intervention (low certainty).

1 finding from 1 review

Probiotics administered to pregnant women at risk of preterm birth vs placebo or no intervention

Miscarriage/stillbirth · preterm infants

Probiotics administered to pregnant women at risk of preterm birth showed no clear difference in miscarriage/stillbirth compared with placebo or no intervention (low certainty).

1 finding from 1 review