Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

21 questions · 21 findings · 2 reviews · Pregnancy and Childbirth · Headline outcomes only

No studies found 8 · 38.1%GRADE not reported 0 · 0%Very low 1 · 4.8%Low 8 · 38.1%Moderate 2 · 9.5%High 2 · 9.5%

Probiotics vs placebo

Diagnosis of gestational diabetes · preventing gestational diabetes

Probiotics showed no clear difference in diagnosis of gestational diabetes mellitus compared with placebo (low certainty).

1 finding from 1 review

Probiotics vs placebo

Mortality or morbidity composite · preventing gestational diabetes

Probiotics showed no clear difference in mortality or morbidity composite compared with placebo (low certainty).

1 finding from 1 review

Probiotics vs placebo

Hypoglycaemia · preventing gestational diabetes

Probiotics showed no clear difference in hypoglycaemia as defined by trialists compared with placebo (low certainty).

1 finding from 1 review

Probiotics vs placebo

Hypertensive disorders of pregnancy: pre‐eclampsia · preventing gestational diabetes

Probiotics leads to higher hypertensive disorders of pregnancy (pre‐eclampsia) compared with placebo (high certainty).

1 finding from 1 review

Probiotics vs placebo

Large‐for‐gestational age · preventing gestational diabetes

Probiotics showed no clear difference in large‐for‐gestational age compared with placebo (moderate certainty).

1 finding from 1 review

Probiotics vs placebo

Perinatal mortality · preventing gestational diabetes

Probiotics showed no clear difference in perinatal mortality (stillbirth and neonatal mortality) compared with placebo (low certainty).

1 finding from 1 review

Probiotics vs placebo

Incidence of mastitis within 6 months postpartum · postpartum breastfeeding women

Probiotics may leads to lower incidence of mastitis within 6 months postpartum compared with placebo (low certainty).

1 finding from 1 review

Probiotics vs placebo

Nipple damage within 6 months postpartum · postpartum breastfeeding women

It is very uncertain whether probiotics changes nipple damage within 6 months postpartum compared with placebo (very low certainty).

1 finding from 1 review