Findings

What do systematic reviews say?

7 questions · 7 findings · 1 reviews · Cystic Fibrosis and Genetic Disorders

No studies found 0 · 0%GRADE not reported 0 · 0%Very low 0 · 0%Low 7 · 100%Moderate 0 · 0%High 0 · 0%

Pulmonary exacerbations · children and adults with CF

1 finding from 1 review

Probiotics for people with cystic fibrosis 2020 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 225 participants
Low

Faecal calprotectin · children and adults with CF

1 finding from 1 review

Probiotics for people with cystic fibrosis 2020 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 177 participants
Low

Adverse events (serious adverse reaction and adverse reaction) · children and adults with CF

Probiotics showed no clear difference in adverse events (serious adverse reaction and adverse reaction) compared with placebo (low certainty).

1 finding from 1 review

Probiotics for people with cystic fibrosis 2020 · Cochrane Headline outcomes only
RR 3 [0.49, 18.46]
5 studies · 310 participants
Low

Weight (z score) · children and adults with CF

1 finding from 1 review

Probiotics for people with cystic fibrosis 2020 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 91 participants
Low

FEV1 % predicted · children and adults with CF

1 finding from 1 review

Probiotics for people with cystic fibrosis 2020 · Cochrane Headline outcomes only
no estimate extracted
5 studies · 284 participants
Low

Hospitalisation (any cause) · children and adults with CF

1 finding from 1 review

Probiotics for people with cystic fibrosis 2020 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 115 participants
Low

HRQoL (PedsQLTM 4.0 SF 15 (Scale from: 0 to 100)) · children and adults with CF

1 finding from 1 review

Probiotics for people with cystic fibrosis 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 37 participants
Low