Prednisone showed no clear difference in persistent kidney disease at any time after treatment compared with placebo or supportive treatment (moderate certainty).
Prednisone showed no clear difference in children with any continuing kidney disease at 3 months compared with placebo or supportive treatment (moderate certainty).
Prednisone showed no clear difference in children with any continuing kidney disease at 6 months compared with placebo or supportive treatment (moderate certainty).
Prednisone showed no clear difference in children with any continuing kidney disease at 12 months compared with placebo or supportive treatment (low certainty).
Prednisone showed no clear difference in number developing severe kidney disease compared with placebo or supportive treatment (low certainty).
Oral cyclophosphamide showed no clear difference in complete remission: all renal pathologies compared with prednisone or placebo (low certainty).
Oral cyclophosphamide showed no clear difference in complete remission: FSGS compared with prednisone or placebo (low certainty).
Oral cyclophosphamide showed no clear difference in complete or partial remission compared with prednisone or placebo (low certainty).
Oral cyclophosphamide showed no clear difference in complete or partial remission: FSGS compared with prednisone or placebo (low certainty).
Oral cyclophosphamide showed no clear difference in treatment failure compared with prednisone or placebo (low certainty).
Oral cyclophosphamide showed no clear difference in adverse events: death (all causes) compared with prednisone or placebo (low certainty).
It is very uncertain whether oral cyclophosphamide changes adverse events: hypertension with seizures compared with prednisone or placebo (very low certainty).
Summary of findings: Tripterygium wilfordii Hook F showed no clear difference in complete remission ( compared with prednisone (low certainty).
Summary of findings: Tripterygium wilfordii Hook F showed no clear difference in partial remission ( compared with prednisone (low certainty).
Summary of findings: Tripterygium wilfordii Hook F showed no clear difference in complete or partial remission ( compared with prednisone (low certainty).