Cochrane · systematic review · CD008568
Tripterygium wilfordii Hook F (a traditional Chinese medicine) for primary nephrotic syndrome
Chen, Y, Gong, Z, Chen, X, et al. · Cochrane Database of Systematic Reviews · 2013 · Cochrane Library
Kidney and TransplantAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
9
current version
GRADE rated
9
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 0 · 0%Low 9 · 100%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Summary of findings: Tripterygium wilfordii Hook F (TwHF) versus no TwHF
Population: patients with primary nephrotic syndrome
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Complete remission ( Summary of findings: Tripterygium wilfordii Hook F (TwHF) vs no TwHF | RR 1.46 [1.18, 1.8] | 4 studies · 293 participants | Low Downgraded: risk of bias, imprecision |
Partial remission ( Summary of findings: Tripterygium wilfordii Hook F (TwHF) vs no TwHF | RR 0.77 [0.49, 1.21] | 4 studies · 293 participants | Low Downgraded: risk of bias, imprecision |
Complete or partial remission ( Summary of findings: Tripterygium wilfordii Hook F (TwHF) vs no TwHF | RR 1.26 [1.1, 1.44] | 4 studies · 293 participants | Low Downgraded: risk of bias, imprecision |
Summary of findings: Tripterygium wilfordii Hook F versus prednisone
Population: patients with primary nephrotic syndrome
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Complete remission ( Summary of findings: Tripterygium wilfordii Hook F vs prednisone | RR 1.09 [0.83, 1.43] | 4 studies · 223 participants | Low Downgraded: risk of bias, imprecision |
Partial remission ( Summary of findings: Tripterygium wilfordii Hook F vs prednisone | RR 1.07 [0.69, 1.65] | 4 studies · 223 participants | Low Downgraded: risk of bias, imprecision |
Complete or partial remission ( Summary of findings: Tripterygium wilfordii Hook F vs prednisone | RR 1.05 [0.92, 1.2] | 4 studies · 223 participants | Low Downgraded: risk of bias, imprecision |
Summary of findings: Comparison of TwHF and CPA
Population: patients with primary nephrotic syndrome
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Complete remission ( | RR 1.06 [0.82, 1.37] | 2 studies · 114 participants | Low Downgraded: risk of bias, imprecision |
Partial remission ( | RR 1.02 [0.46, 2.29] | 2 studies · 114 participants | Low Downgraded: risk of bias, imprecision |
Complete or partial remission ( | RR 1.05 [0.9, 1.23] | 2 studies · 114 participants | Low Downgraded: risk of bias, imprecision |