Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

84 questions · 87 findings · 23 reviews · ENT

No studies found 21 · 24.1%GRADE not reported 0 · 0%Very low 29 · 33.3%Low 26 · 29.9%Moderate 11 · 12.6%High 0 · 0%

Intranasal steroid spray vs placebo or no intervention

Presence of normal olfactory function · people with olfactory dysfunction for less than 4 weeks following COVID‐19 infection

It is very uncertain whether intranasal steroid spray changes presence of normal olfactory function Assessed by participants as a… compared with no intervention/placebo (very low certainty).

2 findings from 1 review

Intranasal steroid drops vs placebo

Presence of normal olfactory function · participants with olfactory dysfunction following COVID‐19 for ≤ 15 days

Intranasal steroid drops showed no clear difference in presence of normal olfactory function Assessed by participants > 4… compared with placebo (low certainty).

1 finding from 1 review

Endolymphatic sac decompression vs placebo (sham surgery)

Improvement in vertigo (complete resolution) at 6 to ≤ 12 months (12 months) · Ménière’s disease

It is very uncertain whether endolymphatic sac decompression changes improvement in vertigo (complete resolution) at 6 to ≤ 12 months (12… compared with placebo (sham surgery) (very low certainty).

1 finding from 1 review