Intranasal steroid spray vs placebo or no intervention: Presence of normal olfactory function
It is very uncertain whether intranasal steroid spray changes presence of normal olfactory function Assessed by participants as a… compared with no intervention/placebo (very low certainty).
What each review found
Include earlier review versions| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Intranasal steroid spray vs no intervention/placebo Presence of normal olfactory function Assessed by participants as a score of 10 on a VAS (range 0 to 10) ≤ 4 weeks · people with olfactory dysfunction for less than 4 weeks following COVID‐19 infection It is very uncertain whether intranasal steroid spray changes presence of normal olfactory function Assessed by participants as a… compared with no intervention/placebo (very low certainty). Interventions for the prevention of persistent post‐COVID‐19 olfactory dysfunction (2022) · Cochrane Headline outcomes only | RR 1.19 [0.85, 1.68] | 1 study · 100 participants | Very low |
Intranasal steroid spray vs no intervention/placebo Presence of normal olfactory function · people with olfactory dysfunction for less than 4 weeks following COVID‐19 infection It is very uncertain whether intranasal steroid spray changes presence of normal olfactory function compared with no intervention/placebo (very low certainty). Interventions for the prevention of persistent post‐COVID‐19 olfactory dysfunction (2022) · Cochrane Headline outcomes only | RR 2.31 [1.16, 4.64] | 1 study · 77 participants | Very low |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Interventions for the prevention of persistent post‐COVID‐19 olfactory dysfunction 2022 · Cochrane Headline outcomes only | Not reported | list not extracted yet | Not assessed |
Studies behind the findings
None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.